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41 - 50 of 97 search results for p53

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  2. Svetlana Khoronenkova | Department of Biochemistry

    https://www.bioc.cam.ac.uk/research/khoronenkova
    23 Jul 2024: ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.

  3. Publications | Centre for Atmospheric Science

    https://www.ch.cam.ac.uk/group/atm/publications?page=14
    18 Jul 2024: Weather. (2020). 75,. 353. (doi: 10.1002/wea.3795). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

  4. Research News Archives - Page 12 of 29 - School of Clinical Medicine

    https://www.medschl.cam.ac.uk/category/schoolnews/research-news/page/12/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  5. Dr Florian Merkle | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/merkle
    23 Feb 2024: For example, we recently showed that hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation

  6. https://www.pdn.cam.ac.uk/taxonomy/term/58/feed

    https://www.pdn.cam.ac.uk/taxonomy/term/58/feed
    23 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

  7. Publications | Knowles Lab

    https://www-knowles.ch.cam.ac.uk/publications
    18 Jul 2024: Journal: Scientific Reports 12 (1). ------------------------------. Characterization of full-length p53 aggregates and their kinetics of formation.

  8. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/brian-huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  9. Publications - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/publications/
    23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.

  10. Search Publications | Publications

    https://publications.maths.cam.ac.uk/publications-search?page=609
    18 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on

  11. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    23 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

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