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23 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-02-06T11:14:05","modified_gmt":"2015-02-06T11:14:05","slug":"publications","status"

23 Feb 2024: consequence of p53 stabilization in response to ribosomal stress.

23 Feb 2024: 2018) Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.

23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Merkel, O., Morrigl, R.,Turner, S.D. and Kenner, L. (2017) When the

3 May 2024: Valle (2011) "Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA".

6 May 2024: s66;P5;P57;P53;P52;P50;P24;N8;s3;s76;d76;N15;s79;N17;N29;N24;s82;s84;d84;/rC:-.3572,3.7125,0;-.3572,2.8875,0;1.0717,2.

23 Feb 2024: Swigart, and G.I. Evan. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Finch, L.B. Swigart, and G.I. Evan. Thepathological response to DNA damage does not contribute to p53-mediated tumour suppression.

23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some

23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.

23 Feb 2024: Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.

23 Feb 2024: P53 Epidemiological evidence to support a tax on Sugar Sweetened Drinks as a measure to address childhood obesity.

23 Feb 2024: and Denizot Y., 2012, Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. ... Magnone V., Cogné M. and Denizot Y., 2011, A p53 defect sensitizes

23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

23 Feb 2024: Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.

15 Jun 2024: Simons. doi:10.1016/j.stem.2010.05.017. Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia.

23 Feb 2024: Cambridge Cardiovascular - Functional Genomics https://www.cardiovascular.cam.ac.uk/directory/research-themes/functional-genomics Functional Genomics theme led by Prof Nicole Soranzo performs epigenomic annotation of cells relevant to the

23 Feb 2024: p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma. Cancer Res.

23 Feb 2024: A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q. –.

14 Aug 2023: For instance, adeno-viruses were programmed to couple their replication to the state of the p53 pathway in human cells93. ... Normal p53 production would result in inhibition of a crucial viral replication component, whereas a defunct p53 pathway, which

23 Feb 2024: P, Aden K.u00a0/spanEpithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.u00a0span class="docsum-journal-citation

3 Apr 2024: Fischle, S.M. Gasserem. /em/p p(53)strongAcetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration./strongbr / a

23 Feb 2024: Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner” Mol Cell.

14 Aug 2023: SYNBIOLOGY. An Analysis of Synthetic Biology Research in Europe and. North America. Final Report on Analysis of Synthetic Biology Sector. September 2006. Deliverable D11. FP6-2003-NEST-B4 Project 015357 – SYNBIOLOGY. European Commission 6th

14 Aug 2023: PRO. JECT. REP. ORT. EU. R 2. 1796. Synthetic BiologyApplying Engineering to Biology. Report of a NEST High-Level Expert Group. Interested in European research? RTD info is our quarterly magazine keeping you in touch with main developments (results,

14 Aug 2023: For example, researchers recently identified the production of multiple copies of p53, a gene known to inhibit cancer growth, in African elephants.

14 Aug 2023: Complex and dynamic transcription regulation of mul-tiple genes and their pathways drives many essential cel-lular activities, including genome replication and repair, cell division and differentiation, and disease progression and inheritance.

23 Feb 2024: Tweddle DA.<br /> p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma.<br /> Cancer Res.

14 Aug 2023: May 2020. The Bio Revolution: Innovations transforming econom. ies, societies, and our lives. The Bio RevolutionInnovations transforming economies, societies, and our lives. McKinsey Global Institute. Since its founding in 1990, the McKinsey Global

23 Feb 2024: Cambridge Immunology Network - Department of Medicine https://www.immunology.cam.ac.uk/departments/medicine en Professor Ravindra Gupta https://www.immunology.cam.ac.uk/staff/professor-ravindra-gupta <div class="field field-name-field-sd-consultancy

30 Apr 2024: Ras) and tumour suppression proteins (e.g. p53, p16/p19ARF or p21) (for review see Hynds et al., 2022; Wang et al., 2022).

23 Feb 2024: Cambridge Immunology Network - Autoimmunity and inflammation https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/autoimmunity-inflammation Investigating the causes of excessive and aberrant immune responses which result in inflammation

23 Feb 2024: Cambridge Immunology Network - MRC Laboratory of Molecular Biology https://www.immunology.cam.ac.uk/departments/mrc-lmb en Conor O'Donovan https://www.immunology.cam.ac.uk/staff/conor-odonovan <div class="field field-name-field-sd-consultancy

23 Feb 2024: Br J Cancer. 2013 Apr 2;108(6):1340-7. doi: 10.1038/bjc.2013.66./pnpa href="http://www.ncbi.nlm.nih.gov/pubmed/23341460"p53 and translation attenuation regulate

23 Feb 2024: Cambridge Immunology Network - Molecular and structural immunology https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/molecular-structural-immunology Molecular and structural techniques are used to address a wide range of

23 Feb 2024: Tweddle DA.<br /> p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma.<br /> Cancer Res.

23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q^– syndrome.

3 Jan 2024: p53 : the gene that cracked the cancer code.

17 Oct 2023: ARI's TAP access to the Gaia Archive. Unique source identifier (unique within a particular Data Release) Basis function coefficients for the BP spectrum representation Basis function coefficients for the RP spectrum representation

23 Aug 2023: Table 13. Power Few Distributions with Counts and Count Ratios……………………. P53.

23 Feb 2024: Published in The Lancet Oncology, researchers evaluated the role of the Cytosponge atypia, p53 overexpression, and clinical risk factors (age, sex, and segment length) to prioritise patients for endoscopy.

1 Nov 2023: University of Dundee University of Dundee Influence of p53 pathway in determining efficacy or toxicity of treatment with novel polo-like kinase-1 (PLK1) targeted anti-cancer therapeutic agents.

5 Dec 2023: Teachers College Record, v.117 n.14, p53-74. Spiro, J.P., (2009) Defending the master race: conservation, eugenics, and the legacy of Madison Grant.

6 Dec 2023: www.electricitypolicy.org.uk. EP. RG. WO. RK. ING. PA. PE. R. Abstract. Lessons from conditionality provisions for south-north cooperation on climate change. EPRG Working Paper 0825 Cambridge Working Paper in Economics 0849. Maike Sippel and Karsten

9 Jul 2023: of the enterprise’ (Miller and Rose, 1998, p53).

29 Jan 2024: Chin, W. Fischle, S.M. Gasser. EMBO J. 2011. 30: 2610-2621. (53) Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.

1 Sep 2023: The Eagle 2023. THE EAGLE 2023 1. The Eagle 2023VOLUME 105. WELCOME. 2. Published in the United Kingdom in 2023 by St John’s College, CambridgeFirst published in the United Kingdom in 1858 by St John’s College, Cambridge. Cover photo by: Rich

14 Aug 2023: Gene-edited organisms in agriculture: Risks and unexpected consequences. Dr. Janet Cotter, Logos Environmental, U.K. and Dana Perls, Friends of the Earth, U.S. Gene-edited organisms in agriculture: Risks and unexpected consequences • Friends of