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LMB Scientists Awarded Prestigious European Grants - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-awarded-prestigious-european-grants/26 Nov 2010: Alan’s grant complements his MRC programme grant on the “Structural Biology of p53”, which started on 1 October 2010. ... 70% of human cancers have p53 directly inactivated by mutation. Alan’s group has found that some 30% of the inactivated -
LMB continues pioneering work started in CPE - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-continues-pioneering-work-started-in-cpe/24 Sep 2010: Alan will continue to lead his research on the p53 tumour suppressor protein at the LMB with an MRC programme grant for the next five years. -
A Relationship between mRNA Expression Levels and Protein Solubility…
www-vendruscolo.ch.cam.ac.uk/tartaglia09jmb.pdf13 Jan 2010: H.(1999). Regulation of p53 function and stability byphosphorylation. Mol. Cell. Biol. -
An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man
https://supfam.mrc-lmb.cam.ac.uk/bioinformatics/people/julian_gough/publications/ravasi_cell_2010.pdf12 Apr 2010: activate NOTCH pathways resulting in p53-dependent cell-cycle. arrest (Ban et al., 2008). ... EWS-FLI1 suppresses NOTCH-activated p53 in Ewing’s sarcoma. Cancer. Res. 68, 7100–7109.
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