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  2. p53 tetramerization domain Family

    https://supfam.mrc-lmb.cam.ac.uk/scop/47720
    Toggle navigation. Go. p53 tetramerization domain. Domain. Species. Proteins. 1. 54.
  3. p53 impairs CRISPR/Cas9 in healthy cells | Department of Biochemistry

    https://www.bioc.cam.ac.uk/news/archive/2018/p53-impairs-crispr-cas9-in-healthy-cells
    22 Jul 2024: RPE-1) cell line activate p53, causing cell growth arrest and DNA repair via the NHEJ pathway. ... A delicate balance is required, however, as p53 inhibition can leave cells vulnerable to tumorigenic mutations.
  4. 18 Jul 2024: Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ... doi:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
  5. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-42
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/42. Reference: P53/43/42.
  6. Tumor suppressor p53 fragments Superfamily

    https://supfam.mrc-lmb.cam.ac.uk/scop/58744
    Toggle navigation. Go. Tumor suppressor p53 fragments. Family. Domains. Species. 2.
  7. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-135
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/135. Reference: P53/43/135.
  8. p53 tetramerization domain Superfamily

    https://supfam.mrc-lmb.cam.ac.uk/scop/47719
    Toggle navigation. Go. p53 tetramerization domain. Family. Domains. Species.
  9. Freeze Frame » Coast from Kangerdlugssuatsiaq to Kialineq (18 August …

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-231
    Reference: P53/43/231. Reference: P53/43/231. Title: Coast from Kangerdlugssuatsiaq to Kialineq (18 August 1930).
  10. p53 DNA-binding domain-like Family

    https://supfam.mrc-lmb.cam.ac.uk/scop/81314
    Toggle navigation. Go. p53 DNA-binding domain-like. Domain. Species. Proteins. 2. 49.
  11. p53 tetramerization domain Fold

    https://supfam.mrc-lmb.cam.ac.uk/scop/47718
    Toggle navigation. Go. p53 tetramerization domain. Superfamily. Families. Domains. 5. 2.
  12. Tumor suppressor p53 fragments Fold

    https://supfam.mrc-lmb.cam.ac.uk/scop/58743
    Toggle navigation. Go. Tumor suppressor p53 fragments. Superfamily. Families. Domains. 1.
  13. p53-like transcription factors Superfamily

    https://supfam.mrc-lmb.cam.ac.uk/scop/49417
    Toggle navigation. Go. p53-like transcription factors. Family. Domains. Species. 3. 5.
  14. Freeze Frame » Coast from Kangerdlugssuatsiaq to Kialineq (18 August …

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-262
    Reference: P53/43/262. Reference: P53/43/262. Title: Coast from Kangerdlugssuatsiaq to Kialineq (18 August 1930).
  15. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-388
    Reference: P53/43/388. Reference: P53/43/388. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).
  16. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-497
    Reference: P53/43/497. Reference: P53/43/497. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (20 July 1931).
  17. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-540
    Reference: P53/43/540. Reference: P53/43/540. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (22 July 1931).
  18. Freeze Frame » Sermilik (?)

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-85
    You are in:Title: Sermilik (?). Reference: P53/43/85. Reference: P53/43/85. Title: Sermilik (?). Description: glass plate negative. Collection: British Arctic Air Route Expedition 1930-31.
  19. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-34
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/34. Reference: P53/43/34.
  20. Freeze Frame » coasts

    https://www.freezeframe.ac.uk/tag/coasts/page/136
    You are logged on as '':username. password.
  21. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-137
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/137. Reference: P53/43/137.
  22. Freeze Frame » Camp at foot of glacier

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-545
    You are in:Title: Camp at foot of glacier. Reference: P53/43/545. Reference: P53/43/545.
  23. Freeze Frame » Watkins Mountains

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-543
    You are in:Title: Watkins Mountains. Reference: P53/43/543. Reference: P53/43/543. Title: Watkins Mountains.
  24. Freeze Frame » Coast from Kangerdlugssuatsiaq to Kialineq (18 August …

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-278
    Reference: P53/43/278. Reference: P53/43/278. Title: Coast from Kangerdlugssuatsiaq to Kialineq (18 August 1930).
  25. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-424
    Reference: P53/43/424. Reference: P53/43/424. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).
  26. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-468
    Reference: P53/43/468. Reference: P53/43/468. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (20 July 1931).
  27. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-535
    Reference: P53/43/535. Reference: P53/43/535. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (22 July 1931).
  28. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3320

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3320
  29. Therapeutic vulnerabilities in lung tumours with distinct p53

    https://www.medschl.cam.ac.uk/therapeutic-vulnerabilities-lung-tumours-distinct-p53-deficiencies/
    23 Feb 2024: School of Clinical Medicine. Featured Articles. Therapeutic vulnerabilities in lung tumours with distinct p53 deficiencies. ... Importantly, the authors identified a similar p53-mutation type specific gene expression signature in human lung tumors.
  30. Alan Fersht | 03 - 05 Sept 2017 Cambridge, UK

    https://www.ch.cam.ac.uk/pfei/alan-fersht
    18 Jul 2024: Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... We discovered that about 30% of oncogenic mutants of p53 are just temperatures sensitive and can, in theory, be rescued by small molecules.
  31. Freeze Frame » Sermilik (?)

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-90
    You are in:Title: Sermilik (?). Reference: P53/43/90. Reference: P53/43/90. Title: Sermilik (?). Description: glass plate negative. Collection: British Arctic Air Route Expedition 1930-31.
  32. Freeze Frame » Sermilik (?)

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-91
    You are in:Title: Sermilik (?). Reference: P53/43/91. Reference: P53/43/91. Title: Sermilik (?). Description: glass plate negative. Collection: British Arctic Air Route Expedition 1930-31.
  33. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-40
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/40. Reference: P53/43/40.
  34. Freeze Frame » coasts

    https://www.freezeframe.ac.uk/tag/coasts/page/137
    You are logged on as '':username. password.
  35. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-134
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/134. Reference: P53/43/134.
  36. Freeze Frame » Coast from Kangerdlugssuatsiaq to Kialineq (18 August …

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-253
    Reference: P53/43/253. Reference: P53/43/253. Title: Coast from Kangerdlugssuatsiaq to Kialineq (18 August 1930).
  37. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-441
    Reference: P53/43/441. Reference: P53/43/441. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).
  38. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-493
    Reference: P53/43/493. Reference: P53/43/493. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (20 July 1931).
  39. Freeze Frame » Coast from Umivik to the south-west corner of…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-533
    Reference: P53/43/533. Reference: P53/43/533. Title: Coast from Umivik to the south-west corner of Angmagssalik Island (22 July 1931).
  40. Freeze Frame » Sermilik (?)

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-88
    You are in:Title: Sermilik (?). Reference: P53/43/88. Reference: P53/43/88. Title: Sermilik (?). Description: glass plate negative. Collection: British Arctic Air Route Expedition 1930-31.
  41. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-48
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/48. Reference: P53/43/48.
  42. Freeze Frame » coasts

    https://www.freezeframe.ac.uk/tag/coasts/page/138
    You are logged on as '':username. password.
  43. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-142
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/142. Reference: P53/43/142.
  44. Freeze Frame » Coast from Kangerdlugssuatsiaq to Kialineq (18 August …

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-240
    Reference: P53/43/240. Reference: P53/43/240. Title: Coast from Kangerdlugssuatsiaq to Kialineq (18 August 1930).
  45. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-409
    Reference: P53/43/409. Reference: P53/43/409. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).
  46. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-419
    Reference: P53/43/419. Reference: P53/43/419. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).
  47. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-35
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/35. Reference: P53/43/35.
  48. Freeze Frame » Sermilik (?)

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-93
    You are in:Title: Sermilik (?). Reference: P53/43/93. Reference: P53/43/93. Title: Sermilik (?). Description: glass plate negative. Collection: British Arctic Air Route Expedition 1930-31.
  49. Freeze Frame » coasts

    https://www.freezeframe.ac.uk/tag/coasts/page/139
    You are logged on as '':username. password.
  50. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-136
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/136. Reference: P53/43/136.
  51. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-425
    Reference: P53/43/425. Reference: P53/43/425. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).

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