Search

23 Jul 2024: Valle (2011) "Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA".

23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

26 Jul 2024: Chiba Ene (PhD Medical Sciences) - Histone demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Activity through Lysine Demethylation.

23 Feb 2024: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. ... CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.

23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

18 Jul 2024: s66;P5;P57;P53;P52;P50;P24;N8;s3;s76;d76;N15;s79;N17;N29;N24;s82;s84;d84;/rC:-.3572,3.7125,0;-.3572,2.8875,0;1.0717,2.

26 Jul 2024: Journal: Scientific Reports 12 (1). ------------------------------. Characterization of full-length p53 aggregates and their kinetics of formation.

23 Feb 2024: Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Cancer Cell, 2006. 10(6): p. 501-14 PMID:17157790. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI The pathological response to DNA damage does not

26 Jul 2024: His work is now focussed on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53 – the so-called “Guardian of the Genome” – in order to design novel

27 Jul 2024: Cancer studies. Including cell cycle and cancer, use of mouse models, genome-wide sequencing and genome-wide disease association, leukaemia, p53, cancer therapeutics, recombinant antibody generation, commercial drug design and development,

23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Kaser Group. Publications. Reviews & Editorials. 2024 University of Cambridge.

27 Jul 2024: Department of Physiology, Development and Neuroscience - Academics https://www.pdn.cam.ac.uk/directory/faculty en Sumru Bayin https://www.pdn.cam.ac.uk/staff/bayin <div class="field field-name-field-sd-consultancy field-type-list-boolean

26 Jul 2024: Mann was originally thought to have been wounded on 29 December 1914 and was recorded as a prisoner of war on 25 March 1915 (Jesus College Society Annual Report, 1916, p53).

26 Jul 2024: Imaging aggregates of P53 and determining the role of these aggregates in the development and spreading of cancer.

27 Jul 2024: CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response. Nat. Med., 24(7):927-930.

27 Jul 2024: Contributors: Ingrida Olendraite; Katherine Brown; Andrew E. Firth. A novel map of human p53 response elements uncovers evidence of selection pressures and variants similar to Li-Fraumeni Syndrome mutations. ... Germline and Somatic Genetic Variants in

26 Jul 2024: J Chem Phys. (2009). 130,. 194508. (doi: 10.1063/1.3131690). Computer Simulations of Peptides from the p53 DNA Binding Domain.

23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Dr Rana's Group. Publications. 2024 University of Cambridge.