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41 - 50 of 97 search results for p53

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  2. Dr Maria Christophorou | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/christophorou
    23 Feb 2024: She did her PhD with Gerard Evan at UCSF, where she was able to dissect the relative contributions of different p53 activating signals towards tumour suppression using mouse models of conditional ... p53 perturbation.

  3. Dr Matthew Cheetham | Yusuf Hamied Department of Chemistry

    https://www.ch.cam.ac.uk/person/mrc79
    26 Jul 2024: Lee. (2023). (doi: 10.1101/2023.02.07.527479). Characterization of full-length p53 aggregates and their kinetics of formation.

  4. Svetlana Khoronenkova | Department of Biochemistry

    https://www.bioc.cam.ac.uk/research/khoronenkova
    27 Jul 2024: ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.

  5. Publications | Clarke Group

    https://www.ch.cam.ac.uk/group/sclarke/publications?page=2
    26 Jul 2024: 1474. (doi: 10.1016/j.bpj.2020.09.007). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

  6. Research News Archives - Page 12 of 29 - School of Clinical Medicine

    https://www.medschl.cam.ac.uk/category/schoolnews/research-news/page/12/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  7. Publications | Centre for Atmospheric Science

    https://www.ch.cam.ac.uk/group/atm/publications?page=14
    26 Jul 2024: Weather. (2020). 75,. 353. (doi: 10.1002/wea.3795). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

  8. https://www.pdn.cam.ac.uk/taxonomy/term/58/feed

    https://www.pdn.cam.ac.uk/taxonomy/term/58/feed
    27 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

  9. Dr Florian Merkle | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/merkle
    23 Feb 2024: For example, we recently showed that hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation

  10. Publications

    https://www-neurosciences.medschl.cam.ac.uk/horvathlab/publications/
    23 Feb 2024: RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels.

  11. Florian T. Merkle - Institute of Metabolic Science-Metabolic Research …

    https://www.mrl.ims.cam.ac.uk/research/principal-investigators/florian-t-merkle/
    23 Feb 2024: For example, hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation from transplanted cells (Merkle ... Human pluripotent stem cells

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