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23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory

23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS)

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory ... strong>This work has revealed key traits

11 May 2024: She leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus.</p> <p>Her team develops new techniques to allow us to visualise better the

In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that the inhibition of PI3Kδ paradoxically

18 Oct 2013: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is

11 May 2024: Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis. Noémie Lefrancq, Department of Genetics. ... These novel insights into Bp dynamics and its interactions with vaccine-induced immunity are highly relevant to vaccination

11 May 2024: The initial detection of a vaccine vector by the innate immune system has long lasting consequences for the development of memory responses. ... We use vaccinia virus, the vaccine that was developed to eradicate smallpox to help understand these

23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests:&nbsp;</div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire