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Previous Seminar Series Talks | Department of Pharmacology
https://www.phar.cam.ac.uk/previous-seminar-series-talks15 May 2024: 17th Febuary. Dr Shafaq Sikander. William Harvey Research Institute. Endogenous and immunological mechanisms of musculoskeletal pain. -
Group Summaries for Alumni | Department of Pharmacology
https://www.phar.cam.ac.uk/group-summaries-alumni15 May 2024: derived from the most clinically advanced AURKA inhibitor, alisertib, that are able to clear both endogenous and exogenous AURKA from cells and to downregulate its interphase functions. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/lindon/pub15 May 2024: Cell density-dependent induction of endogenous myogenin (myf4) gene expression by Myf5. -
Phar Cambridge RSS Paper feed | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator/sources/2215 May 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the -
Multi-disciplinary approach to investigate the molecular basis of G…
https://www.phar.cam.ac.uk/research/Ladds15 May 2024: Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Irvine/pubs15 May 2024: 2010) Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases II and II and a partial nuclear localisation of the II isoform. ... Irvine. R.F. (2007) Genomic tagging of endogenous Type IIβ phosphatidylinositol 5-phosphate 4 -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/taylor/Pub15 May 2024: Mol. Pharm. 92, 533-545. Keebler, MV & Taylor CW (2017) Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites. ... 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. Biochem. J. -
Funded PhD Opportunities | Department of Pharmacology
https://www.phar.cam.ac.uk/postgraduate/studentships15 May 2024: It should also be possible to explore the effects of endogenous modulators to some degree by altering the concentrations of Ca2+, Mg2and ATP in the pipette solution. -
Innovating Protein Technologies for Therapeutic and Vaccine Design |…
https://www.phar.cam.ac.uk/research/Howarth15 May 2024: Nature Nanotechnology. 2023 Mar;18(3):290-298. NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins. -
Designer proteins to seek and destroy | Department of Pharmacology
https://www.phar.cam.ac.uk/news/BBSRC-funded-project15 May 2024: These will be adapted in two applications: First, the disruption of endogenous protein-protein interactions to control and direct cellular processes in which they are involved.
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