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Natural Sciences Tripos Part II Pharmacology or Biological and ...
https://www.phar.cam.ac.uk/system/files/documents/2020Coursebrochure.pdfsystems, whether the drug is synthetic, natural or endogenous. Pharmacologists. can use this information to reveal how the biological system itself works. -
Innovating Protein Technologies for Therapeutic and Vaccine Design |…
https://www.phar.cam.ac.uk/research/Howarth30 Apr 2024: Nature Nanotechnology. 2023 Mar;18(3):290-298. NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins. -
Feed aggregator | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator30 Apr 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the -
Research Interest | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/research30 Apr 2024: We are also using new methods to aid in the de-orphanisation (identification of endogenous agonists) for olfactory receptors. -
Department of Pharmacology, Tennis Court Road, Cambridge, CB2 1PD ...
https://www.phar.cam.ac.uk/sites/www.phar.cam.ac.uk/files/part_ii_pharmacology_2023_2024_course_handbook_-_copy.pdf8 Feb 2024: natural or endogenous. -
Group Summaries for Alumni | Department of Pharmacology
https://www.phar.cam.ac.uk/group-summaries-alumni30 Apr 2024: derived from the most clinically advanced AURKA inhibitor, alisertib, that are able to clear both endogenous and exogenous AURKA from cells and to downregulate its interphase functions. -
Dr Cathy Wilson | Department of Pharmacology
https://www.phar.cam.ac.uk/news/wilson30 Apr 2024: Her main area of research is to develop therapeutic strategies to either inhibit Myc driven transcription to develop new cancer therapies or enhance Myc driven transcription to stimulate endogenous tissue repair. -
Multi-disciplinary approach to investigate the molecular basis of G…
https://www.phar.cam.ac.uk/research/Ladds30 Apr 2024: Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/taylor/Pub30 Apr 2024: Mol. Pharm. 92, 533-545. Keebler, MV & Taylor CW (2017) Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites. ... 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. Biochem. J. -
Research | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Howarth/research30 Apr 2024: We have developed a new class of binding proteins that form covalent bonds to endogenous protein targets.
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