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Research | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Howarth/research30 Apr 2024: We have developed a new class of binding proteins that form covalent bonds to endogenous protein targets. -
Research Interest | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/research30 Apr 2024: We are also using new methods to aid in the de-orphanisation (identification of endogenous agonists) for olfactory receptors. -
Recent Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/aggregator/sources/1230 Apr 2024: Both are Ca2+-permeable and regulated by phosphoinositides, principally PI(3,5)P2. Accumulating evidence has uncovered synergistic channel activation by PI(3,5)P2 and endogenous metabolites such as the -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Irvine/pubs30 Apr 2024: 2010) Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases II and II and a partial nuclear localisation of the II isoform. ... Irvine. R.F. (2007) Genomic tagging of endogenous Type IIβ phosphatidylinositol 5-phosphate 4 -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/pub30 Apr 2024: M. & Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. ... 2020) Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/lindon/pub30 Apr 2024: Cell density-dependent induction of endogenous myogenin (myf4) gene expression by Myf5. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/rahman/pub30 Apr 2024: 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/taylor/Pub30 Apr 2024: Mol. Pharm. 92, 533-545. Keebler, MV & Taylor CW (2017) Endogenous signalling pathways and caged-IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites. ... 3. receptors requires an endogenous 1-8-14 calmodulin-binding motif. Biochem. J. -
Projects available for October 2024 | Department of Pharmacology
https://www.phar.cam.ac.uk/postgraduate/abstracts30 Apr 2024: Indicating we can reprogram an organ with extremely limited endogenous regenerative potential towards cardiomyogenesis. -
Previous Seminar Series Talks | Department of Pharmacology
https://www.phar.cam.ac.uk/previous-seminar-series-talks30 Apr 2024: 17th Febuary. Dr Shafaq Sikander. William Harvey Research Institute. Endogenous and immunological mechanisms of musculoskeletal pain.
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