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Research
https://www2.mrc-lmb.cam.ac.uk/groups/nguyen/research/We develop biochemical methods to obtain protein-nucleic acid complexes involved in telomere maintenance pathways both from endogenous sources and by overexpression methods. -
Reprogramming translation
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/reprogramming-translation/In the first step we created an orthogonal ribosome that is selectively directed to a new orthogonal message that is not read by endogenous ribosomes. ... We first selected, on 5FU, for sequences upstream of the cat-upp fusion that do not allow the gene -
Protein labeling and imaging
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/protein-labeling/Note that despite endogenous amber codons we see minimal background labeling of non-target proteins, either on the cell surface or intracellularly. -
Photochemical genetics
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/photochemical-genetics/Comparison of the kinetics of ERK2–GFP nuclear accumulation following MEK photoactivation or endogenous receptor stimulation provided some interesting insights. -
Insight on Research - Page 44 of 58 - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/news-events/insight-on-research/page/44/Published on. 20 April, 2015. The existence of an endogenous daily clock in humans is well known: it is what drives the 24-hour sleep/wake rhythm to match the daily -
Insight on Research - Page 41 of 58 - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/news-events/insight-on-research/page/41/This “endogenous” formaldehyde is ubiquitous, and sufficient amounts might be produced that could damage our cells. -
Insight on Research - Page 38 of 58 - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/news-events/insight-on-research/page/38/Published on. 11 August, 2016. HIV is a retrovirus, meaning it has to copy its RNA genome into DNA in order to infect cells. -
Insight on Research - Page 25 of 58 - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/news-events/insight-on-research/page/25/These are endogenous daily rhythms that […]. Uncharged DNA-like molecules can store genetic information and function like antibodies. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9259
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9259HIV is a retrovirus, meaning it has to copy its RNA genome into DNA in order to infect cells. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7892
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/7892This was because endogenous formaldehyde destroyed the blood stem cells residing in the bone marrow. ... In these patients reducing or counteracting endogenous formaldehyde production may be of therapeutic value.
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