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Activation of GCN2 by the ribosomal P-stalk
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/PNAS_2019.pdf7 Mar 2019: Yeast GCN2 forms aconstitutive dimer even in the absence of activation, principallythrough the CTD (24, 25). ... This lack of clarity was further con-founded by a more recent report that, unlike yeast, mouseGCN2 does not form a stable complex that -
LMB 365 - Day 297 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-297/24 Oct 2019: Published on. 24 October, 2019. Day 297 of #LMB365 is a screenshot from our internal “Bee Cam”. -
Activation of lysosomes allows worms to live longer and may protect…
https://www2.mrc-lmb.cam.ac.uk/activation-of-lysosomes-allows-worms-to-live-longer-and-may-protect-against-neurodegenerative-diseases/17 Jul 2019: Ageing is a growing problem for society, particularly because of the associated increased risk of developing disease. Understanding how we might be able -
LMB 365 - Day 144 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-144/23 May 2019: Published on. 24 May, 2019. As the sun comes out on day 144 of LMB365 Andrew McKenzie and members of his group in the LMB’s PNAC Division take advantage of -
Claudia Bonfio receives the Royal Society of Chemistry’s 2019 Dalton…
https://www2.mrc-lmb.cam.ac.uk/claudia-bonfio-receives-the-royal-society-of-chemistrys-2019-dalton-emerging-researcher-award/7 May 2019: Claudia Bonfio, a postdoctoral researcher in John Sutherland’s group in the LMB’s PNAC Division, has been awarded the Royal Society of Chemistry’s 2019 -
LMB 365 - Day 267 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-267/24 Sep 2019: Published on. 24 September, 2019. LMB scientists will be taking C. -
LMB 365 - Day 83 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-83/23 Mar 2019: Published on. 24 March, 2019. LMB Nobel Laureate John Kendrew was born on this day in Oxford in 1917. -
Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/PDF/Publications/acs.biochem.9b00296.pdf31 Jul 2019: leucine zipper motifs.24,25. -
Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: The stalled ribosome triggers the ‘no-go’ or ‘nonstop’ pathways of mRNA decay10,13,17,18, nascent protein degra-dation via ribosome-associated quality control12,19–23 and ribosome ... 24,25,30,31). A second mechanism involves detecting the -
Functionalized graphene sheets on gold grids aid structure…
https://www2.mrc-lmb.cam.ac.uk/functionalized-graphene-sheets-on-gold-grids-aid-structure-determination-by-electron-cryo-microscopy/19 Jun 2019: Naydenova, K., Peet, MJ., Russo, CJ. PNAS 116(24): 11718-11724.
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