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Scientific Glossary - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-glossary/21 Jul 2023: Scientific Glossary A glossary of terms used in Insight on Research stories: Alternative splicing Atomic resolution Connectomics DNA crosslinks History of -
Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: CD: 200 minutes, MRC LMB. Francis Crick. Francis Crick interviewed by Soraya de Chadarevian and Leslie Orgel, 14 October 1997. ... DVD: 200 minutes, The Biochemical Society. Sequences: Dr Fred Sanger interviewed by Horace Judson. -
Activation of the integrated stress response by inhibitors of its…
https://www2.mrc-lmb.cam.ac.uk/activation-of-the-integrated-stress-response-by-inhibitors-of-its-kinases/8 Sep 2023: These findings are important because ISR kinase inhibitors have been used in over 200 pre-clinical studies during the past 10 years, but at the concentrations broadly used, these compounds activate -
Raphin 1 and phosphatase inhibitors technology (2018) - MRC…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/raphin1-2018/21 Jul 2023: Finding a way to selectively inhibit these enzymes is important because there are about 200 different phosphatases, controlling all aspects of cell biology, and this could open up a broad range -
The patterned assembly and stepwise Vps4-mediated disassembly of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hurtig%202023%20sciadv.ade5224.pdf16 Jul 2023: STK strains were supplemented with 200 μM EdU(Thermo Fisher Scientific, C10639) for 10 min. ... Three microliters of resus-pended cells were applied to a freshly glow-discharged QuantifoilAu 200 mesh R2/2 or R2/1 grid. -
LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: The LMB is simply having a wonderful Christmastime! Day 347 of #LMB365 shows the restaurant decked in festive finery, ready to welcome over 200 people for a delicious 3 course lunch ... Each machine is used to pour both standard and specially requested -
Behind the scenes: Stephen Holmes and a surprising career switch to…
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-stephen-holmes/15 Dec 2023: Since we’ve moved in, we’ve doubled the amount of high-power server facilities from 200 to 400 kilowatts. -
Substrate-driven assembly of a translocon for multipass membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Nature_2022b.pdf19 Aug 2023: 4c). ΔGapp9.8–0.4–3.7. ΔGapp1. –0.32. –0.33. –3.7. YIPF1(1–200) Sec61β(201–221)N. Flag1 2. YIPF1. ... The 221-residue Flag–YIPF1(1–200)–Sec61β series was generated by Gibson cloning DNA fragments (Twist Biosciences) into a -
Diverse cytomotive actins and tubulins share a polymerization switch…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Wagstaff%202023Sci%20Advances%20cytomotive%20switch%20sciadv.adf3021.pdf16 Jul 2023: The exchanged tubulin wasthen injected onto a Superdex 200 3.2/300 column (GE Health-Care), equilibrated, and eluted in 80 mM K-Pipes, 100 μM Na-GDP, 100 μM MgCl2, ... A total of 2.5 μl was appliedto a gold-on-gold grid (UltrAuFoil R2/2 200 mesh),
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