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Dr Rachael Bashford-Rogers | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/rachaelbf23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution -
https://www.path.cam.ac.uk/taxonomy/term/9/feed
https://www.path.cam.ac.uk/taxonomy/term/9/feed9 May 2024: Contrasting effects of linezolid on healthy and dysfunctional human neutrophils: reducing C5a-induced injury. ... Monocytes control second-phase neutrophil emigration in established LPS-induced murine lung injury. -
The Academy of Medical Sciences announces election of new Fellows…
https://www.cam.ac.uk/research/news/the-academy-of-medical-sciences-announces-election-of-new-fellows-202112 May 2021: the process by which new variants likely arise, and also reporting the first data on Pfizer BioNTech vaccine-induced antibody responses against the B.1.1.7 ‘Kent UK’ variant. ... His research investigates the basis for pathological immune activation -
Julia Kenyon
https://www.homerton.cam.ac.uk/people/julia-kenyonShe leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus. ... Viruses 3(11) 2192-2213. Kenyon JC, Lever AML (2011) XMRV, Prostate Cancer and Chronic Fatigue Syndrome. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed9 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
Professor Willem H Ouwehand - Department of Haematology
https://www.haem.cam.ac.uk/staff/senior-staff/professor-willem-h-ouwehand/23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed9 May 2024: Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. 2019. Cell Metabolism. ... Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed9 May 2024: CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. ... 2009). Multiple redundant stress resistance mechanisms are induced i<i>n Salmonella enterica </i>serovar Typhimurium<i> </i>in response to modulation -
Dr Sara Lear | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/sara.lear%40nhs.net23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe -
https://www.path.cam.ac.uk/taxonomy/term/7/feed
https://www.path.cam.ac.uk/taxonomy/term/7/feed9 May 2024: 29875319.pdf" target="_blank">[PDF]</a></p> <p><a href="http://www.ncbi.nlm.nih.gov/pubmed/29540581" target="_blank"><b>Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes ... ncbi.nlm.nih.gov/pubmed/28530713" target="_blank"><b>BACH2 -
Dr Edward Banham-Hall | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/banham-hall23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS. -
Discovery of the genetic basis of a rare immune disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-the-genetic-basis-of-a-rare-immune-disease/22 Oct 2013: The researchers first examined genetic information from individuals who suffer from immunodeficiency and are predisposed to infections. ... The newly identified disease has been called Activated PI3K-δ Syndrome (APDS) after the enzyme that is affected -
Member: Anna Jane Dreyer - Cambridge Neuroscience
https://neuroscience.cam.ac.uk/member/annajanedreyer1/My current project involves investigating the role of socioeconomic inequalities in the dementia syndromes associated with frontotemporal lobar degeneration and Parkinson's disease. ... Moving on From HAND: Why We Need New Criteria for Cognitive -
Professor Gillian M Griffiths FMedSci, FRS | Cambridge Immunology…
https://www.immunology.cam.ac.uk/Networkdirectory/gg305%40cam.ac.uk23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome. -
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. -
Publications - Genetic and functional mechanisms of susceptibility to …
tb.med.cam.ac.uk/publications-2/Durandy A. #. (. #. corresponding authors):Occurrence of B-cell lymphomas in patients with activated phosphoinositide 3-kinase δ syndrome. ... A, Doffinger R, Gilmour KC, Henriquez F, Thrasher AJ, Gaspar HB, Nejentsev S:Immunodeficiency and disseminated -
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/16 Feb 2024: An investigation of RF networks and RF mean levels/p pApril Le: Neurophysiological biomarkers of dementia in Down Syndrome/p pSharon Neufeld: Does mental health treatment promote family functioning to mitigate ... of change/p pLucie Aman: Markers of risk -
tb.med.cam.ac.uk/feed/
tb.med.cam.ac.uk/feed/25 Jun 2015: protecting from infection./p pstrongGenetic analyses of patients with Primary Immunodeficiencies/strong/p pPrimary Immunodeficiencies (PIDs) comprise a heterogeneous group of genetic disorders that affect functioning of the immune system and -
Scientists discover genetic disease which causes recurrent…
https://www.med.cam.ac.uk/blog/scientists-discover-genetic-disease-which-causes-recurrent-respiratory-infections/23 Feb 2024: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is -
Cambridge University Reporter Special
https://www.reporter.admin.cam.ac.uk/reporter/2006-07/weekly/6051/13.html28 Jan 2022: The appearance of Human Immunodeficiency Virus (HIV), Severe Acute Respiratory Syndrome (SARS) virus, and new variants of Avian Influenza are well-documented examples.
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