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Evolving nature of the AP2 a-appendage hubduring clathrin-coated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T -
Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf15 Aug 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble. -
Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf23 Nov 2004: J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P. -
“The LMB provides an unsurpassed environment for both new ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=1885218 Jan 2021: Francis Crick and James Watson, 1962 - discovery of the structure of DNA. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=6676da809a77717190652162 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/35191
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/35191 -
Perutz Student Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-student-prize/24 Oct 2023: Perutz Student Prize The Perutz Student Prize is awarded annually for outstanding work performed at LMB prior to the award of a Ph.D. Nominees
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Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: Functional Depletion of Mahoguninby Cytosolically Exposed Prion ProteinContributes to NeurodegenerationOishee Chakrabarti1 and Ramanujan S. Hegde1,1Cell Biology and Metabolism Program, National Institute of Child Health and Human Development, -
Fast Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/fast-facts/21 Jul 2023: Francis Crick and Jim Watson helped unravel the structure of DNA – one of the scientific landmarks of the 20th century – in the MRC Unit. ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine),
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Eileen Southgate Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/eileen-southgate-prize/24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion
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Photographs - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/photographs/21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or
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coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J. -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x77.html24 Aug 2021: watson_crick_pair() : c-interface.h. ... watson_crick_pair_for_residue_range() : c-interface.h. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32{"id":32,"date":"2012-06-25T09:59:05","date_gmt":"2012-06-25T09:59:05","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=32"},"modified":"2023-07-21T12:49:29","modified_gmt":"2023-07-21T11:49:29","slug":"scientific-models","status" -
LMB Nobel Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry).
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Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=6676da81681e1171906521711 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985{"id":1985,"date":"2012-07-18T16:07:14","date_gmt":"2012-07-18T15:07:40","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1985"},"modified":"2021-03-30T15:06:15","modified_gmt":"2021-03-30T14:06:15","slug":"francis-crick-1916-2004 -
Scientific Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/21 Jul 2023: Base plate from the Watson and Crick 1953 model. Signed by Francis Crick and Jim Watson. ... A year later I was able to get Jim Watson’s signature when he stopped by the LMB on a visit.’ Arthur Arnone, 28 October 2003.
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Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969{"id":20969,"date":"2021-08-06T16:48:14","date_gmt":"2021-08-06T14:48:08","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=20969"},"modified":"2021-11-18T14:33:20","modified_gmt":"2021-11-18T14:33:20","slug":"herbert-freddie-gutfreund","st -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968{"id":1968,"date":"2012-07-18T15:55:14","date_gmt":"2012-07-18T14:55:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1968"},"modified":"2021-05-21T13:29:26","modified_gmt":"2021-05-21T12:29:26","slug":"lmb-alumni-carl-ivar-br -
Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November
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Kiyoshi Nagai (1949 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/kiyoshi-nagai-1949-2019/2 Oct 2019: In this last complex, the detailed description of non-Watson-Crick base pairs between the 3’ splice site AG dinucleotide and both the branch-point adenosine and the 5’ splice site
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4122
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4122 -
Books - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/21 Jul 2023: DNA. The Big Idea: Crick, Watson & DNA. Strathern, Paul. London: Arrow Books, 1997. ... The involvement of RNA in the synthesis of nucleic acids’ by James Watson.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995{"id":21995,"date":"2022-01-05T11:54:57","date_gmt":"2022-01-05T11:54:21","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=21995"},"modified":"2022-01-05T12:18:56","modified_gmt":"2022-01-05T12:18:56","slug":"donald-caspar-1927-2021","stat -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26{"id":26,"date":"2012-06-25T09:58:08","date_gmt":"2012-06-25T09:58:08","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=26"},"modified":"2023-07-21T12:49:27","modified_gmt":"2023-07-21T11:49:27","slug":"photographs","status":"publ -
History of the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/history-of-the-lmb/21 Jul 2023: Nobel Prize for Physiology or Medicine: Francis Crick and Jim Watson.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8882
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8882 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892{"id":28892,"date":"2022-12-15T10:50:17","date_gmt":"2022-12-15T10:50:17","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=28892"},"modified":"2022-12-15T10:51:51","modified_gmt":"2022-12-15T10:51:51","slug":"lmb-through-the-years-60-years-of-me -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997{"id":997,"date":"2012-07-03T09:13:21","date_gmt":"2012-07-03T09:13:21","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=997"},"modified":"2023-07-21T12:49:21","modified_gmt":"2023-07-21T11:49:21","slug":"fast-facts","status":"pub -
Site Map - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/site-map/21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Site Map.
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Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M.,
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Michael Fuller (1936 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/michael-fuller-1936-2019/28 Nov 2019: This was especially apt, as Michael was already working in the Laboratory when Francis Crick and James Watson announced the structure of DNA and unveiled their model, in 1953.
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LMB Alumni List - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/11 Jun 2024: LMB Alumni List This is an alphabetical listing of past members of the LMB, complete with tenure dates. The list has been compiled by cross-referencing
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Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14{"id":14,"date":"2012-06-25T09:56:10","date_gmt":"2012-06-25T09:56:10","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=14"},"modified":"2023-07-21T12:49:24","modified_gmt":"2023-07-21T11:49:24","slug":"history-of-the-lmb","status -
1982 - Aaron Klug - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1982-aaron-klug/21 Jul 2023: 1982 Chemistry Prize - Aaron Klug “for his development of crystallographic electron microscopy and his structural elucidation of biologically important
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1980 - Fred Sanger - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1980-fred-sanger/21 Jul 2023: 1980 Chemistry Prize - Fred Sanger “for their contributions concerning the determination of base sequences in nucleic acids”
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1997 - John Walker - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1997-john-walker/21 Jul 2023: 1997 Chemistry Prize - John Walker “for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)”
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1958 - Fred Sanger - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1958-fred-sanger/21 Jul 2023: 1958 Chemistry Prize - Fred Sanger “for his work on the structure of proteins, especially that of insulin”
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Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…
https://www2.mrc-lmb.cam.ac.uk/moments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing/6 Dec 2010: Search this website. Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing. ... Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing.
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2017 - Richard Henderson - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/2017-richard-henderson/21 Jul 2023: 2017 Chemistry Prize - Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... content/uploads/james_watson-33x50.jpg 33w" sizes="(max-width: 130px) 100vw, 130px" //pnulnliDiscovering the double helix. -
Coot Scripting Interface: c-interface.h File Reference
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html24 Aug 2021: Coot Scripting Interface 7000. c-interface.h File Reference. Coot Scripting Interface - General. Functions. SCM . merge_molecules (SCM add_molecules, int imol). merge molecules More.. cis_peptides (int imol). return cis_peptide info for imol. -
Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/30 Mar 2021: He will be best remembered for DNA, whose structure he discovered with Jim Watson in 1953.
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Elife 6. 2016. García-Nafría, J., Herguedas, B., Watson, J.F., Greger, I.H. -
New mechanism found that maintains intracellular water balance - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-mechanism-found-that-maintains-intracellular-water-balance/18 Oct 2023: Joseph Watson led the imaging studies and yeast experiments, Estere Seinkmane led proteomic and phosphoproteomic analyses and Christine Styles led the cell viability and cell adaptation experiments. ... Further references. Watson, JL., Seinkmane, E.,
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