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LMB 365 - Day 100 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-100%2F&format=xmlBy simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology can -
LMB 365 - Day 278 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-278%2F&format=xmlThis was the LMB’s second Nobel for 1962, Francis Crick and James Watson had already been awarded the Physiology and Medicine Prize for their work on the structure of DNA. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/publications/Madan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik N, Begum F, Boulanger J, Bauer K, Kiebler MA, Derivery E and Bullock SL (2023) HEATR5B associates with -
LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: This was the LMB’s second Nobel for 1962, Francis Crick and James Watson had already been awarded the Physiology and Medicine Prize for their work on the structure of DNA.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/9046
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/904622","modified_gmt":"2019-03-21T11:26:22","slug":"dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick","status":"publish","type":"post","link":"https://www2.mrc-lmb.cam.ac.uk/ ... dna-discovery-pioneer-james-watson-pays-tribute-colleagu -
EMBO Awards - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/embo-awards/10 Jan 2024: EMBO Awards & Honours The European Molecular Biology Organisation (EMBO) was founded in 1964 to promote molecular biology in Europe. Its aim is to
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nature14896 493..505
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/95_Brown_A_Nature_2015.pdf19 Aug 2015: with its Watson–Crick edge. ... 4b, c). The main chain of Cys127 from the YxCxxxFmotif can form two hydrogen bonds with the Watson–Crick edge ofA1825 to stabilize its flipped orientation, facilitating stacking of the 12and -
doi:10.1016/j.molcel.2008.05.027
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK%20MolCell%202008%20Lowe.pdf16 Aug 2008: In. the overlapping regions, Watson-Crick base pairs form be-. tween the different strands, though the DNA used is blunt-. -
DNA 60th Anniversary celebrated at Cambridge - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdna-60th-anniversary-celebrated-at-cambridge%2F&format=xml25th April 1953, Francis Crick and Jim Watson published their groundbreaking paper in Nature, in which they revealed to the world the double. -
doi:10.1016/j.neuron.2005.05.004
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Jockusch_Neuron2005.pdf17 Jun 2005: Neuron 17, 1241–1249. Miele, A.E., Watson, P.J., Evans, P.R., Traub, L.M., and Owen, D.J.(2004). -
Tyrosine Residues in Phospholipase C�2 Essential for the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf20 Apr 2002: Tyrosine Residues in Phospholipase C2 Essential for the EnzymeFunction in B-cell Signaling. Received for publication, August 8, 2001, and in revised form, October 9, 2001Published, JBC Papers in Press, October 17, 2001, DOI 10.1074/jbc.M107577200. -
PII: S1097-2765(03)00356-3
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf27 Oct 2003: genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J. -
Interactive Tools forCryo-EM Map Fitting Paul EmsleyMRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-June-PSI.pdf19 Jun 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble. -
Evolving nature of the AP2 a-appendage hubduring clathrin-coated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T -
Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf15 Aug 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697 -
Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf23 Nov 2004: J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P. -
Emmanuel Derivery - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/emmanuel-derivery/23 Feb 2024: Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M., Planelles-Herrero, VJ., Chambers, JE., Manton, JD., Baker, D., Derivery, E. ... Watson, J.L., Aich, S., Oller-Salvia, B., Drabek, A.A., Blacklow, S.C., Chin, J., Derivery E.
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DNA discovery pioneer James Watson pays tribute to colleague Francis…
https://www2.mrc-lmb.cam.ac.uk/dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick/10 Jun 2016: Search this website. DNA discovery pioneer James Watson pays tribute to colleague Francis Crick. ... Published on. 10 June, 2016. James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth.
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“The LMB provides an unsurpassed environment for both new ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=1885218 Jan 2021: Francis Crick and James Watson, 1962 - discovery of the structure of DNA. -
Academy of Medical Sciences - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/academy-medical-sciences/21 May 2024: Academy of Medical Sciences The Academy of Medical Sciences is an independent body in the UK that represents the diverse spectrum of medical science –
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LMB Nobel Prizes - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/21 Jul 2023: LMB Nobel Prizes Nobel Prizes are international awards administered by the Nobel Foundation in Stockholm, Sweden. They are awarded annually for
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Andrew Travers - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/andrew-travers/14 Mar 2024: After this he took a couple of years out as a post-doc in Jim Watson’s lab at Harvard University where he co-discovered the first of the RNA polymerase
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Bart Barrell (1944-2023) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/bart-barrell-1944-2023/6 Dec 2023: Physiology or Medicine Prize to Francis Crick, James Watson and Maurice Wilkins for determining the structure of DNA, and the 1962 Chemistry Prize to Max Perutz and John Kendrew for their
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John O'Neill - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/john-oneill/26 Mar 2024: Cell). Watson et al. (2023).
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Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=66855b8fdcdc817200157592 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
Simon Bullock - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/simon-bullock/5 Mar 2024: Nat Struct Mol Biol, s41594-024-01212-x. Madan V., Albacete-Albacete L., Jin L., Scaturro P., Watson J.L., Muschalik N., Begum F., Boulanger J., Bauer K., Kiebler M.A.,
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Royal Society Awards - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/royal-society-awards/16 May 2024: Royal Society Awards & Honours The Royal Society is a Fellowship of the world's most eminent scientists and is the oldest scientific academy in
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Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: Functional Depletion of Mahoguninby Cytosolically Exposed Prion ProteinContributes to NeurodegenerationOishee Chakrabarti1 and Ramanujan S. Hegde1,1Cell Biology and Metabolism Program, National Institute of Child Health and Human Development, -
Joan A. Steitz Postdoc Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/steitz-postdoc-prize/24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion
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Perutz Student Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-student-prize/24 Oct 2023: Perutz Student Prize The Perutz Student Prize is awarded annually for outstanding work performed at LMB prior to the award of a Ph.D. Nominees
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Fast Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/fast-facts/21 Jul 2023: Francis Crick and Jim Watson helped unravel the structure of DNA – one of the scientific landmarks of the 20th century – in the MRC Unit. ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine),
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Eileen Southgate Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/eileen-southgate-prize/24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion
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coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. -
Published Research - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/published-research/21 Jul 2023: Stockwell, I., Watson, JF., Greger, IH. (1st July 2024).
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Photographs - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/photographs/21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J. -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x77.html24 Aug 2021: watson_crick_pair() : c-interface.h. ... watson_crick_pair_for_residue_range() : c-interface.h. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32{"id":32,"date":"2012-06-25T09:59:05","date_gmt":"2012-06-25T09:59:05","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=32"},"modified":"2023-07-21T12:49:29","modified_gmt":"2023-07-21T11:49:29","slug":"scientific-models","status" -
LMB Nobel Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry).
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Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=66855b90363bb172001576011 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985{"id":1985,"date":"2012-07-18T16:07:14","date_gmt":"2012-07-18T15:07:40","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1985"},"modified":"2021-03-30T15:06:15","modified_gmt":"2021-03-30T14:06:15","slug":"francis-crick-1916-2004 -
Scientific Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/21 Jul 2023: Base plate from the Watson and Crick 1953 model. Signed by Francis Crick and Jim Watson. ... A year later I was able to get Jim Watson’s signature when he stopped by the LMB on a visit.’ Arthur Arnone, 28 October 2003.
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Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969{"id":20969,"date":"2021-08-06T16:48:14","date_gmt":"2021-08-06T14:48:08","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=20969"},"modified":"2021-11-18T14:33:20","modified_gmt":"2021-11-18T14:33:20","slug":"herbert-freddie-gutfreund","st -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968{"id":1968,"date":"2012-07-18T15:55:14","date_gmt":"2012-07-18T14:55:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1968"},"modified":"2021-05-21T13:29:26","modified_gmt":"2021-05-21T12:29:26","slug":"lmb-alumni-carl-ivar-br -
Kiyoshi Nagai (1949 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/kiyoshi-nagai-1949-2019/2 Oct 2019: In this last complex, the detailed description of non-Watson-Crick base pairs between the 3’ splice site AG dinucleotide and both the branch-point adenosine and the 5’ splice site
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Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November
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Books - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/21 Jul 2023: DNA. The Big Idea: Crick, Watson & DNA. Strathern, Paul. London: Arrow Books, 1997. ... The involvement of RNA in the synthesis of nucleic acids’ by James Watson.
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