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Tyrosine Residues in Phospholipase C�2 Essential for the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf20 Apr 2002: Tyrosine Residues in Phospholipase C2 Essential for the EnzymeFunction in B-cell Signaling. Received for publication, August 8, 2001, and in revised form, October 9, 2001Published, JBC Papers in Press, October 17, 2001, DOI 10.1074/jbc.M107577200. -
Fast Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/fast-facts/21 Jul 2023: Francis Crick and Jim Watson helped unravel the structure of DNA – one of the scientific landmarks of the 20th century – in the MRC Unit. ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine),
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Eileen Southgate Prize - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/eileen-southgate-prize/24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion
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Published Research - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/published-research/21 Jul 2023: Nature [Epub ahead of print]. Stockwell, I., Watson, JF., Greger, IH.
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PII: S1097-2765(03)00356-3
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf27 Oct 2003: genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J. -
Photographs - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/photographs/21 Jul 2023: Photographs The LMB has an extensive collection of photographs and images, a selection of which can be viewed here by either browsing the collection or
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Interactive Tools forCryo-EM Map Fitting Paul EmsleyMRC Laboratory of …
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-June-PSI.pdf19 Jun 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble. -
Evolving nature of the AP2 a-appendage hubduring clathrin-coated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T -
Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf15 Aug 2018: Base-stacking restraints:(parallel plane restraints). LIBG Restraints. (Watson Crick and) Wobble, Reverse Wobble. -
Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf23 Nov 2004: J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P. -
“The LMB provides an unsurpassed environment for both new ...
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=1885218 Jan 2021: Francis Crick and James Watson, 1962 - discovery of the structure of DNA. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=668aac7a95e6c17203641542 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: Functional Depletion of Mahoguninby Cytosolically Exposed Prion ProteinContributes to NeurodegenerationOishee Chakrabarti1 and Ramanujan S. Hegde1,1Cell Biology and Metabolism Program, National Institute of Child Health and Human Development, -
coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 16311.85.2 watson-crick-pair. 16411.85.3 watson-crick-pair-for-residue-range. 164. xix. 11.86 Sequence (Assignment). 16411.86.1 print-sequence-chain. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32{"id":32,"date":"2012-06-25T09:59:05","date_gmt":"2012-06-25T09:59:05","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=32"},"modified":"2023-07-21T12:49:29","modified_gmt":"2023-07-21T11:49:29","slug":"scientific-models","status" -
LMB Nobel Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry).
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J. -
Coot Scripting Interface: File Members
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x77.html24 Aug 2021: watson_crick_pair() : c-interface.h. ... watson_crick_pair_for_residue_range() : c-interface.h. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985{"id":1985,"date":"2012-07-18T16:07:14","date_gmt":"2012-07-18T15:07:40","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1985"},"modified":"2021-03-30T15:06:15","modified_gmt":"2021-03-30T14:06:15","slug":"francis-crick-1916-2004 -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=668aac7b788ee172036415511 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
Scientific Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/21 Jul 2023: Base plate from the Watson and Crick 1953 model. Signed by Francis Crick and Jim Watson. ... A year later I was able to get Jim Watson’s signature when he stopped by the LMB on a visit.’ Arthur Arnone, 28 October 2003.
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Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969{"id":20969,"date":"2021-08-06T16:48:14","date_gmt":"2021-08-06T14:48:08","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=20969"},"modified":"2021-11-18T14:33:20","modified_gmt":"2021-11-18T14:33:20","slug":"herbert-freddie-gutfreund","st -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1968{"id":1968,"date":"2012-07-18T15:55:14","date_gmt":"2012-07-18T14:55:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1968"},"modified":"2021-05-21T13:29:26","modified_gmt":"2021-05-21T12:29:26","slug":"lmb-alumni-carl-ivar-br -
Kiyoshi Nagai (1949 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/kiyoshi-nagai-1949-2019/2 Oct 2019: In this last complex, the detailed description of non-Watson-Crick base pairs between the 3’ splice site AG dinucleotide and both the branch-point adenosine and the 5’ splice site
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Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November
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Books - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/21 Jul 2023: DNA. The Big Idea: Crick, Watson & DNA. Strathern, Paul. London: Arrow Books, 1997. ... The involvement of RNA in the synthesis of nucleic acids’ by James Watson.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/26{"id":26,"date":"2012-06-25T09:58:08","date_gmt":"2012-06-25T09:58:08","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=26"},"modified":"2023-07-21T12:49:27","modified_gmt":"2023-07-21T11:49:27","slug":"photographs","status":"publ -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/28892{"id":28892,"date":"2022-12-15T10:50:17","date_gmt":"2022-12-15T10:50:17","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=28892"},"modified":"2022-12-15T10:51:51","modified_gmt":"2022-12-15T10:51:51","slug":"lmb-through-the-years-60-years-of-me -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997{"id":997,"date":"2012-07-03T09:13:21","date_gmt":"2012-07-03T09:13:21","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=997"},"modified":"2023-07-21T12:49:21","modified_gmt":"2023-07-21T11:49:21","slug":"fast-facts","status":"pub -
History of the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/history-of-the-lmb/21 Jul 2023: Nobel Prize for Physiology or Medicine: Francis Crick and Jim Watson.
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Site Map - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/site-map/21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Site Map.
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Michael Fuller (1936 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/michael-fuller-1936-2019/28 Nov 2019: This was especially apt, as Michael was already working in the Laboratory when Francis Crick and James Watson announced the structure of DNA and unveiled their model, in 1953.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1018
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1018{"id":1018,"date":"2012-07-03T09:31:54","date_gmt":"2012-07-03T09:31:54","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1018"},"modified":"2023-07-21T12:49:56","modified_gmt":"2023-07-21T11:49:56","slug":"published-research","st -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14{"id":14,"date":"2012-06-25T09:56:10","date_gmt":"2012-06-25T09:56:10","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=14"},"modified":"2023-07-21T12:49:24","modified_gmt":"2023-07-21T11:49:24","slug":"history-of-the-lmb","status -
1982 - Aaron Klug - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1982-aaron-klug/21 Jul 2023: 1982 Chemistry Prize - Aaron Klug “for his development of crystallographic electron microscopy and his structural elucidation of biologically important
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1980 - Fred Sanger - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1980-fred-sanger/21 Jul 2023: 1980 Chemistry Prize - Fred Sanger “for their contributions concerning the determination of base sequences in nucleic acids”
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Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M.,
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Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…
https://www2.mrc-lmb.cam.ac.uk/moments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing/6 Dec 2010: Search this website. Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing. ... Moments of Genius: Nobel laureate Venki Ramakrishnan describes how James Watson discovered DNA base pairing.
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1997 - John Walker - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1997-john-walker/21 Jul 2023: 1997 Chemistry Prize - John Walker “for their elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP)”
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1958 - Fred Sanger - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1958-fred-sanger/21 Jul 2023: 1958 Chemistry Prize - Fred Sanger “for his work on the structure of proteins, especially that of insulin”
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2017 - Richard Henderson - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/2017-richard-henderson/21 Jul 2023: 2017 Chemistry Prize - Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in
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Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&2 May 2013: Watson & Crick). Recommended reading: Liga0on Independent Cloning Aslanidis C, de Jong PJ. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... content/uploads/james_watson-33x50.jpg 33w" sizes="(max-width: 130px) 100vw, 130px" //pnulnliDiscovering the double helix. -
Coot Scripting Interface: c-interface.h File Reference
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html24 Aug 2021: Coot Scripting Interface 7000. c-interface.h File Reference. Coot Scripting Interface - General. Functions. SCM . merge_molecules (SCM add_molecules, int imol). merge molecules More.. cis_peptides (int imol). return cis_peptide info for imol. -
LMB Alumni List - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/11 Jun 2024: LMB Alumni List This is an alphabetical listing of past members of the LMB, complete with tenure dates. The list has been compiled by cross-referencing
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Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/30 Mar 2021: He will be best remembered for DNA, whose structure he discovered with Jim Watson in 1953.
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Elife 6. 2016. García-Nafría, J., Herguedas, B., Watson, J.F., Greger, I.H.
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