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  2. PK and PKPD studies to support Respiratory and Immunology research

    https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:08pm, 25 Apr 2024 Page 4 of 8. development is very rapid and animals become sexually mature in a matter of weeks. ... Downloaded: 9:08pm, 25 Apr 2024 Page 5 of 8. What are the expected severities and the proportion of animals in each
  3. Exploring Bioelectronic Approaches to Nervous System Restoration in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/exploring_bioelectronic_approaches_to_nervous_system_restoration_in_large_animals_non-technical_sum_redacted.pdf
    30 Apr 2024: Downloaded: 9:30pm, 25 Apr 2024 Page 2 of 10. The Secretary of State has determined that a retrospective assessment of this licence is notrequired. ... Downloaded: 9:30pm, 25 Apr 2024 Page 6 of 10. Because of these reasons, we need to use animals for our
  4. Mouse developmental genetics to study neurodevelopment and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:31pm, 25 Apr 2024 Page 3 of 10. regeneration in the human brain. ... Downloaded: 9:31pm, 25 Apr 2024 Page 7 of 10. normal development and disease.
  5. Neurobehavioural Mechanisms Underlying Mood, Anxiety and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf
    30 Apr 2024: Downloaded: 9:42pm, 25 Apr 2024 Page 2 of 10. Reason for retrospective assessment. ... Downloaded: 9:42pm, 25 Apr 2024 Page 8 of 10. funding at similar levels.
  6. New treatments for renal and liver disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatments_for_renal_and_liver_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:29pm, 25 Apr 2024 Page 6 of 11. can receive is limited. ... Downloaded: 9:29pm, 25 Apr 2024 Page 8 of 11. How have you estimated the numbers of animals you will use?
  7. Tissue response following synovial joint injury and potential for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/tissue_response_following_synovial_joint_injury_and_potential_for_therapies_to_restore_joint_structu_redacted.pdf
    30 Apr 2024: Downloaded: 8:57pm, 25 Apr 2024 Page 4 of 8. Typically, what will be done to an animal used in your project? ... Downloaded: 8:57pm, 25 Apr 2024 Page 6 of 8. How have you estimated the numbers of animals you will use?
  8. Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:27pm, 25 Apr 2024 Page 5 of 11. The project will utilise normal wild type or genetically modified mice. ... Downloaded: 9:27pm, 25 Apr 2024 Page 8 of 11. very rare and access to them is very unpredictable.
  9. Pharmacological evaluation of imaging agents and development of…

    https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf
    30 Apr 2024: Downloaded: 9:45pm, 25 Apr 2024 Page 3 of 11. 2. Biological evaluation. ... Downloaded: 9:45pm, 25 Apr 2024 Page 7 of 11. Non-recovery: 75%.
  10. Control of equine herpesviruses in the horse

    https://www.ubs.admin.cam.ac.uk/system/files/public/control_of_equine_herpesviruses_in_the_horse._non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:01pm, 25 Apr 2024 Page 4 of 11. Unfortunately, the use of ponies for our research is essential. ... Downloaded: 9:01pm, 25 Apr 2024 Page 7 of 11. replicate to reduce the chances having a non-responding blood donor.
  11. The diversity of glia in health, development and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_diversity_of_glia_in_health_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:38pm, 25 Apr 2024 Page 2 of 11. Contains severe procedures. ... Downloaded: 9:38pm, 25 Apr 2024 Page 9 of 11. is on understanding adult mechanisms.
  12. 3Rs Minutes 6th January 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_060121_redacted.pdf
    14 May 2024: Page 1 of 3. Minutes. Date Wednesday, 06/01/2021 Time 09.00am. To Committee Members At Virtual via Microsoft Teams. ... Page 3 of 3. 12. Any Other Business. • The committee discussed AWERB 3Rs TOR and the purpose of the meeting. •
  13. Potent monoclonal antibodies for biologics discovery (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/potent_monoclonal_antibodies_for_biologics_discovery_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:46pm, 25 Apr 2024 Page 6 of 12. Mild severity - 100%. ... Downloaded: 9:46pm, 25 Apr 2024 Page 9 of 12. the 5-year license period.
  14. Development of nerve neuroprosthetic treatment

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_nerve_neuroprosthetic_treatments_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:06pm, 25 Apr 2024 Page 8 of 12. ex vivo systems in studying long-term interactions. ... Downloaded: 9:06pm, 25 Apr 2024 Page 12 of 12. use of training protocols for each procedure.
  15. Development of novel therapeutics for pain (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_novel_therapeutics_for_pain_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:43pm, 25 Apr 2024 Page 3 of 11. conditions and validate our targets. ... Downloaded: 9:43pm, 25 Apr 2024 Page 5 of 11. and analysis to determine any biological effects.
  16. Multi-tissue mechanics in the development and engineering of the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/multi-tissue_mechanics_in_the_development_and_engineering_of_the_posterior_body_axis_non-technical_redacted.pdf
    30 Apr 2024: Downloaded: 9:40pm, 25 Apr 2024 Page 2 of 9. What's the aim of this project? ... Downloaded: 9:40pm, 25 Apr 2024 Page 6 of 9. dish (in vitro).
  17. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: Downloaded: 9:23pm, 25 Apr 2024 Page 3 of 8. Who or what will benefit from these outputs, and how? ... Downloaded: 9:23pm, 25 Apr 2024 Page 4 of 8. the sexes kept apart in their groups of 3-5 animals.
  18. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:11pm, 25 Apr 2024 Page 3 of 11. Who or what will benefit from these outputs, and how? ... Downloaded: 9:11pm, 25 Apr 2024 Page 4 of 11. Our choice of species for this licence is mice.
  19. Vaccine development and fundamental reseach on viruses of medical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:20pm, 25 Apr 2024 Page 2 of 12. Animal types Life stages. ... Downloaded: 9:20pm, 25 Apr 2024 Page 5 of 12. observed for a period of up to 14 days.
  20. Early life origins of heart disease in mammals (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/early_life_origins_of_heart_disease_in_mammals_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:25pm, 25 Apr 2024 Page 3 of 12. in different vessels (e.g. ... Downloaded: 9:25pm, 25 Apr 2024 Page 5 of 12. subsequent molecular studies).
  21. Investigating the niche of mucosal parasitic nematodes and their…

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf
    30 Apr 2024: Downloaded: 9:19pm, 25 Apr 2024 Page 11 of 12. - Carefully consider needle gauge, and keeping volumes and doses to the minimum necessary, for injection of substances. - ... Downloaded: 9:19pm, 25 Apr 2024 Page 12 of 12. RSPCA website: http://science.rspca

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