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  2. Potent monoclonal antibodies for biologics discovery (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/potent_monoclonal_antibodies_for_biologics_discovery_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:46pm, 25 Apr 2024 Page 6 of 12. Mild severity - 100%. ... Downloaded: 9:46pm, 25 Apr 2024 Page 9 of 12. the 5-year license period.
  3. Development of nerve neuroprosthetic treatment

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_nerve_neuroprosthetic_treatments_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:06pm, 25 Apr 2024 Page 8 of 12. ex vivo systems in studying long-term interactions. ... Downloaded: 9:06pm, 25 Apr 2024 Page 12 of 12. use of training protocols for each procedure.
  4. Development of novel therapeutics for pain (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_novel_therapeutics_for_pain_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:43pm, 25 Apr 2024 Page 3 of 11. conditions and validate our targets. ... Downloaded: 9:43pm, 25 Apr 2024 Page 5 of 11. and analysis to determine any biological effects.
  5. Multi-tissue mechanics in the development and engineering of the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/multi-tissue_mechanics_in_the_development_and_engineering_of_the_posterior_body_axis_non-technical_redacted.pdf
    30 Apr 2024: Downloaded: 9:40pm, 25 Apr 2024 Page 2 of 9. What's the aim of this project? ... Downloaded: 9:40pm, 25 Apr 2024 Page 6 of 9. dish (in vitro).
  6. 3Rs Minutes 7th October 2020 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_071020_redacted.pdf
    14 May 2024: Page 1 of 3. Minutes. Date Wednesday, 07/10/2020 Time 08.30am. To Committee Members At Virtual via Microsoft Teams. ... 3Rs information/reports. Page 3 of 3. 9. Feedback from previous Retrospective Reviews None.
  7. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: Downloaded: 9:23pm, 25 Apr 2024 Page 3 of 8. Who or what will benefit from these outputs, and how? ... Downloaded: 9:23pm, 25 Apr 2024 Page 4 of 8. the sexes kept apart in their groups of 3-5 animals.
  8. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:11pm, 25 Apr 2024 Page 3 of 11. Who or what will benefit from these outputs, and how? ... Downloaded: 9:11pm, 25 Apr 2024 Page 4 of 11. Our choice of species for this licence is mice.
  9. Vaccine development and fundamental reseach on viruses of medical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:20pm, 25 Apr 2024 Page 2 of 12. Animal types Life stages. ... Downloaded: 9:20pm, 25 Apr 2024 Page 5 of 12. observed for a period of up to 14 days.
  10. Early life origins of heart disease in mammals (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/early_life_origins_of_heart_disease_in_mammals_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:25pm, 25 Apr 2024 Page 3 of 12. in different vessels (e.g. ... Downloaded: 9:25pm, 25 Apr 2024 Page 5 of 12. subsequent molecular studies).
  11. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: Downloaded: 9:47pm, 25 Apr 2024 Page 7 of 10. Which non-animal alternatives did you consider for use in this project? ... Downloaded: 9:47pm, 25 Apr 2024 Page 8 of 10. To minimise animal usage, we will:.
  12. Investigating the niche of mucosal parasitic nematodes and their…

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf
    30 Apr 2024: Downloaded: 9:19pm, 25 Apr 2024 Page 11 of 12. - Carefully consider needle gauge, and keeping volumes and doses to the minimum necessary, for injection of substances. - ... Downloaded: 9:19pm, 25 Apr 2024 Page 12 of 12. RSPCA website: http://science.rspca
  13. Metabolic basis of microglia function in development (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/metabolic_basis_of_microglia_function_in_development_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:28pm, 25 Apr 2024 Page 2 of 13. Reason for retrospective assessment. ... Downloaded: 9:28pm, 25 Apr 2024 Page 4 of 13. Who or what will benefit from these outputs, and how?
  14. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: Downloaded: 9:02pm, 25 Apr 2024 Page 2 of 11. What's the aim of this project? ... Downloaded: 9:02pm, 25 Apr 2024 Page 7 of 11. mouse the most appropriate model system.
  15. The genetic and developmental basis of morphological and behavioural…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_genetic_and_developmental_basis_of_morphological_and_behavioural_variation_in_cichlid_fishes_no_redacted.pdf
    30 Apr 2024: Downloaded: 9:46pm, 25 Apr 2024 Page 6 of 11. dividers will have holes where females can go through. ... Downloaded: 9:46pm, 25 Apr 2024 Page 7 of 11. we do not expect this protocol to induce any suffering, harm or distress.
  16. Determining mechanisms of tumour development and relapse following…

    https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:12pm, 25 Apr 2024 Page 7 of 11. Which non-animal alternatives did you consider for use in this project? ... Downloaded: 9:12pm, 25 Apr 2024 Page 11 of 11. randomly assigned to treatment groups and attempts will be made to blind studies.
  17. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf
    30 Apr 2024: Downloaded: 9:00pm, 25 Apr 2024 Page 3 of 10. needs for treatments. ... Downloaded: 9:00pm, 25 Apr 2024 Page 9 of 10. costs (harms) to the animals.
  18. Mechanisms underpinning neuronal excitability in health and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_underpinning_neuronal_excitability_in_health_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:26pm, 25 Apr 2024 Page 8 of 14. Why do you need to use animals to achieve the aim of your project? ... Downloaded: 9:26pm, 25 Apr 2024 Page 10 of 14. Overall numbers have been estimated based upon two key factors:. •
  19. Provision of an outsourced drug development platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_development_platform_for_the_treatment_of_bleeding_disorders_non-te_redacted.pdf
    30 Apr 2024: Downloaded: 9:29pm, 25 Apr 2024 Page 2 of 12. Reason for retrospective assessment. ... Downloaded: 9:29pm, 25 Apr 2024 Page 11 of 12. if preventative treatments are being tested.
  20. Interventions in pregnancy effects of obesity on maternal and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf
    30 Apr 2024: Downloaded: 8:52pm, 25 Apr 2024 Page 8 of 13. the mouse's tail. ... Downloaded: 8:52pm, 25 Apr 2024 Page 10 of 13. objectives, if any.
  21. AWERB 3Rs Minutes 5th October 2022 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_051022_redacted.pdf
    14 May 2024: Page 1 of 3. Minutes. Date Wednesday, 05/10/2022 Time 9:00 AM. ... Page 2 of 3. • Section 3.3 Names of other people to be removed. •

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