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Cell, Vol. 85, 217–228, April 19, 1996, Copyright 1996 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/5_Hegde_RS_Cell_1996.pdf25 Apr 1997: Furthermore, because the epi-and its entry into the translocation channel, whereas a. ... Although the length of time that the nents, demonstrated the requirement for a surprisinglychain is exposed to the cytosol is brief, it is significant. -
16262551036386 1..32
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf14 Jul 2021: Shi et al., 2020; Higashi et al., 2020) and does so in the absence of Scc3 without entry inside the. ... chore protein Ctf19, a requirement that is apparently not bypassed by smc1D588Y. -
Cellular/Molecular Endophilin Drives the Fast Mode of Vesicle…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Llobet%20J%20Neurosci2011.pdf23 Sep 2011: All data are expressed as mean SEM Entries in bold are significantly different from the other conditions using a one-way ANOVA followed by Dunnett’s multiple-comparisons test (p ... J Neurosci Methods76:1–5. Sato K, Ernstrom GG, Watanabe S, Weimer RM, -
Substrate-driven assembly of a translocon for multipass membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Nature_2022b.pdf19 Aug 2023: The ER also contains members of the Oxa1 superfamily of TMD insertases9, including the guided entry of tail anchored protein (GET) complex10, the ER membrane protein complex (EMC)11 and TMCO1 ... 2f and Extended Data Fig. 4b). This is consistent with the -
The Function, Structure, and Origins of the ER Membrane Protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Annual_Rev_Biochem_2022.pdf11 Apr 2022: investigation of tail-anchored (TA)membrane protein insertion by the GET (guided entry of TA protein) pathway provided anunexpected insight that ultimately led to the discovery of a key EMC function. ... Although GET3and EMC2 are unrelated proteins, they -
Molecular Biology of the CellVol. 19, 3463–3476, August 2008 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/51_Ashok_A_MBC_2008.pdf16 Jul 2008: Molecular Biology of the CellVol. 19, 3463–3476, August 2008. Retrotranslocation of Prion Proteins from the EndoplasmicReticulum by Preventing GPI Signal TransamidationAarthi Ashok and Ramanujan S. Hegde. Cell Biology and Metabolism Program, -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/227
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/227{"id":227,"date":"2012-06-25T12:46:57","date_gmt":"2012-06-25T11:46:29","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=227"},"modified":"2024-04-04T16:31:10","modified_gmt":"2024-04-04T15:31:10","slug":"student-placement-scheme" -
Membrane Protein Insertion at the Endoplasmic Reticulum
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/75_Shao_S_Ann_Rev_2011.pdf9 Nov 2011: This strongly disfavors its translocation into the lumen, a requirement for sampling the type Itopology. -
Protein targeting and degradation are coupled for elimination of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/73_Hessa_T_Nature_2011.pdf14 Jul 2011: 2e andSupplementary Fig. 13), correlating with the requirements for ubiqui-tination (Fig. ... 4f). Ribosomessynthesizing nascent membrane proteins can recruit both the SRPand Bag6 complex on entry of the first hydrophobic segment intothe ribosomal tunnel4 -
doi:10.1016/j.devcel.2005.09.001
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/37_Shaffer_KL_DevCell_2005.pdf7 Oct 2005: 2002), different requirements for ac-cessory translocon components such as TRAM (Voigtet al., 1996) or the TRAP complex (Fons et al., 2003),and the choice of translocation pathway taken by thesubstrate ... In fact, since the signal sequences of Crtnd -
JCB: Article The Rockefeller University Press $30.00J. Cell Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/J%20Cell%20Biol%202010%20Howes.pdf24 Aug 2011: 6 F). To test the requirement for CLIC endocytosis during mi-gration, this inactivation assay was applied to migrating fibro-blasts. -
Dbouk 1..13
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/vadas_science_signaling.pdf5 Dec 2012: The inhibitoryactivity of the myristoylated peptide required its entry into the cells be-cause both myristoylated and TAT-tagged peptides inhibited Gbg-dependentactivation of Akt, whereas unmodified peptide had no such ... With regard to the requirement -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: 130081, published 7 August 20133 2013 Open Biol. Harvey T. McMahon and David M. GloverTetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, the plasma membrane and contractile ring in cytokinesis. F-BAR protein -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/24
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/24{"id":24,"date":"2012-06-25T09:57:52","date_gmt":"2012-06-25T09:57:52","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=24"},"modified":"2023-07-21T12:49:26","modified_gmt":"2023-07-21T11:49:26","slug":"manuscripts-correspondence" -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739{"id":20739,"date":"2021-07-29T11:20:57","date_gmt":"2021-07-29T10:20:57","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=20739"},"modified":"2021-07-29T11:20:57","modified_gmt":"2021-07-29T10:20:57","slug":"testing-the-capacity-for-intracellul -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/12771
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/12771However we are mindful that the extent of research opportunities can vary a lot as do the length undergraduate courses, master requirements, and all these are put into context when evaluating ... nnnn. If you have heard of us, spread the word or enrol -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19288
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19288{"id":19288,"date":"2020-10-23T13:47:37","date_gmt":"2020-10-23T12:47:37","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=19288"},"modified":"2021-11-18T14:49:58","modified_gmt":"2021-11-18T14:49:58","slug":"opening-of-lmb-containment-level-3-l -
Manuscripts & Correspondence - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/manuscripts-correspondence/21 Jul 2023: Gonville and Caius. July 1953. Bound photocopy. Miscellaneous collection of Crick material has been collected by Mark Bretscher – see entry under BRETSCHER, Mark. ... Dissertations submitted for the degree of Doctor of Philosophy in the University of
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Key Dates for Applicants - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/key-dates-for-applicants/6 Sep 2023: 22nd December 2023 – 3rd January 2024. LMB Postgraduate Office Christmas closure.
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Overview of admissions - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/overview-of-admissions/12 Sep 2023: However we are mindful that the extent of research opportunities can vary a lot as do the length undergraduate courses, master requirements, and all these are put into context when evaluating ... If you have heard of us, spread the word or enrol for the
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