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Mouse developmental genetics to study neurodevelopment and disease…
https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf30 Apr 2024: others, as a point of entry to study neural stem cells in mammalian systems. ... Importantly, in the long term, this project will provide a springboard to utilize endogenous neural stem cells as therapeutic entry points for regenerative medicine in the -
Code of Practice for the Housing and Care of ...
https://www.ubs.admin.cam.ac.uk/files/cop_housing_care_for_sci_purp.pdf18 Sep 2015: r Sci. entifi. c Pu. rpos. esC. onte. nts 4.15 Specific requirements of breeding animals 79. ... There are often highly conflicting interests between the scientific requirements and the needs of the animal. -
Concordat on Openness on Animal Research in the UKAnnual ...
https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf15 Nov 2023: This requirement has led to a substantial increase in the amount and depth of information about animal research in the public domain. ... ON. AN. IMA. L RESEARCH IN T. HE U. K. Minimum compliance requirements. -
Development of Live Bacterial Therapeutics to treat diseases with…
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf29 Apr 2024: Germ-free mice are bred and housed in iso-cages within 'bubbles' or large contained isolators which prevent the entry of viruses or bacteria. ... We will continue to work with animal care staff to assess the requirement for anaesthetic use. -
PPL number: | Granted: 09 Sep 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_for_the_treatment_of_cancer_nts_redacted.pdf13 Sep 2021: Germ-free mice are bred and housed in cages within 'bubbles' or large contained isolators which prevent the entry of viruses or bacteria. ... We will continue to work with animal care staff to assess the requirement for anaesthetic use. -
Biobehavioural basis of the individual vunerability to impulsive…
https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_the_individual_vulnerability_to_impulsivecompulsive_spectrum_disorders_redacted.pdf29 Apr 2024: in the dopamine reward pathway, which is instead the point of entry of addictive drugs to exert their rewarding effects. ... Overall, with a requirement of 48 to 96 rats per experiment, we have used 6000 rats in the last five years in spite of the COVID -
PPL number: | Granted: 20 Nov 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/cell_competition_and_the_dynamics_of_tumour_development_in_epithelial_tissues_nts_redacted.pdf20 Aug 2021: Entry into this programme is often preceded by phase of “field cancerization” in which the acquisition of mutations in certain cancer genes, known as driver genes, enable cells to outcompete their ... Therefore, in planning to maintaining 10 lines at
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