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Refined Structure of (alpha)(beta)-Tubulin at 3.5 A Resolution
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/jmb%20tubulin%20refinement.pdf3 Nov 2001: Anders andD. Botstein, personal communication), in furtheragreement with the requirement of these residuesfor nucleotide hydrolysis. ... Initial amplitudes were obtainedfrom 94 electron diffraction patterns, which had an over-all Friedel R-factor of 19 % -
articles Nucleotide-dependent conformational changes in dynamin:…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Stowell_McMahon1999.pdf30 Apr 1999: articles. entry into nerves is stimulated by the depolarization of nerve termi-nals, the phosphatase calcineurin is activated and amphiphysin anddynamin are dephosphorylated, potentially allowing them tointeract13. ... 28. Steinweis, P. C. & Gilman, A. G. -
Abstract_Book_HMM_v2
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/JM_Abstract_Book.pdf15 Sep 2011: In an attempt to identify the upstream activator of Rac1 in IL-2R entry, we tested the role of p85α and PI 3- Kinase. ... could lead to the recruitment and/or the activation of Rac1 in the clathrin- and caveolin-independent entry used by IL-2R uptake. == -
Membrane fusion is the process whereby two separate lipid ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensMcMahon2008.pdf16 May 2008: Further-more, enveloped viruses gain entry into the cytosol by fusing their limiting membranes with host cell membranes (FIG. ... Analogous to the requirement of HOpS for efficient vacuole fusion. in yeast, the tethering factor and rab5 effector eeA1 is -
Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: LTR, long terminal repeat; FLAG, antibody tag; IRES, internalribosome entry site; SP, signal peptide (the sequences shown are for the nls or memb.). ... Proc Natl Acad SciUSA 93: 6665–6670. Rangarajan A, Hong SJ, Gifford A, Weinberg RA (2004) Species- -
Quality and quantity control at the endoplasmic reticulum
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/65_Hegde_RS_COCB_2010.pdf7 Jun 2010: Given the ability of certain proteins to insert in,and possibly traverse the lipid bilayer spontaneously, withno essential requirement for membrane proteins demon-strated [34], alternatives to protein-conducting channelsshould probably ... 20! Bernasconi -
01Eichler(Hedge)
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/33_Hegde_RS_Chapter_2005.pdf31 Oct 2005: By contrast, translocation into the ER (open arrow) is often regarded as a constitutive process wherethe presence of a signal sequence in a protein predetermines its entry into the ER. ... Thus, the entry of proteins into the ER is not necessarilya -
JFCregg_OGS_finaledit
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/Cregg_thesis.pdf14 Dec 2010: Caenorhabditis Elegans. A dissertation submitted in partial satisfaction of the. requirements for the degree Doctor of Philosophy. ... entry’ to the UK for five months. Dr. Arnivan Ghosh for his ability as a committee. -
N402_18f 313..320
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10580505.pdf11 Nov 1999: protein kinase Lck30 (PDB entry 3lck). c, Stereo diagram of PI3Kg active site with bound. ... Different structural requirements within the switch II region of the Ras protein for. -
FtsA forms actin-like protofilaments
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBO2012FtsAPiotr/emboj201276a.pdf27 Mar 2012: the requirement for ZipA, which is another Z-ring membrane. anchor in E. -
Membrane transport between compartments in eukary-otic cells requires …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynaminreview2004.pdf2 Feb 2004: Membrane transport between compartments in eukary-otic cells requires proteins that allow the budding andSCISSION of nascent cargo vesicles from one compartmentand their targeting and fusion with another. Just asSNARES are proposed to be essential -
doi:10.1016/j.cell.2006.10.032
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/43_Kang_SW_Cell_2006.pdf30 Nov 2006: such diversity in sequence, efficiency, or complexity in. their requirements for additional factors. ... that acts to minimize PrP entry into and misfolding within. the ER lumen. -
The mechanisms of integral membrane protein biogenesis
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf22 Sep 2021: The minimum requirement for SRP recognition is a predominantly hydrophobic sequence of approximately seven amino acids. ... e | Tail- anchored (TA) protein insertion by the guided entry of TA protein (GET) pathway. -
Target Selection during Protein Quality Control
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/96_Shao_S_TIBS_2016.pdf18 Feb 2016: In yeast, Sgt2 clients can be trans-ferred to the TRC40 homolog Get3 (guided entry of tail-anchored proteins 3) via the Get4–Get5bridging complex, with Get5 recruiting Sgt2 and Get4 ... This dual requirement wouldsharpen client discrimination by -
doi:10.1016/j.molcel.2004.08.004
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15350214.pdf24 Sep 2004: The observedsubstrate inhibition by Ins(1,4,5)P3 and non-linear kinetics with ATP(data not shown) may be caused by a requirement for ATP to bindbefore -
coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 11.2 What is Coot? 11.3 What Coot is Not. 11.4 Hardware Requirements. ... 1.4 Hardware Requirements. The code is designed to be portable to any Unix-like operating system.
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