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16 Nov 2011: insertion into the ER43. Although this and subsequent studies showed that insertion was protein and ATPdependent43–46, the molecular basis of this energy requirement and the factors involved in insertion remained ... The high level of conservation

28 Sep 2012: 11.2 What is Coot? 11.3 What Coot is Not. 11.4 Hardware Requirements. ... 1.4 Hardware Requirements. The code is designed to be portable to any Unix-like operating system.

14 Jun 2007: Many plasma-membrane proteins are in a constant flux throughout the internal trafficking pathways of the cell. Some receptors, such as that for transferrin, are continuously internalized into recycling endosomes and returned to the cell surface.

25 Apr 1997: Furthermore, because the epi-and its entry into the translocation channel, whereas a. ... Although the length of time that the nents, demonstrated the requirement for a surprisinglychain is exposed to the cytosol is brief, it is significant.

14 Jul 2021: Shi et al., 2020; Higashi et al., 2020) and does so in the absence of Scc3 without entry inside the. ... chore protein Ctf19, a requirement that is apparently not bypassed by smc1D588Y.

23 Sep 2011: All data are expressed as mean SEM Entries in bold are significantly different from the other conditions using a one-way ANOVA followed by Dunnett’s multiple-comparisons test (p ... J Neurosci Methods76:1–5. Sato K, Ernstrom GG, Watanabe S, Weimer RM,

16 Jul 2008: Molecular Biology of the CellVol. 19, 3463–3476, August 2008. Retrotranslocation of Prion Proteins from the EndoplasmicReticulum by Preventing GPI Signal TransamidationAarthi Ashok and Ramanujan S. Hegde. Cell Biology and Metabolism Program,

19 Aug 2023: The ER also contains members of the Oxa1 superfamily of TMD insertases9, including the guided entry of tail anchored protein (GET) complex10, the ER membrane protein complex (EMC)11 and TMCO1 ... 2f and Extended Data Fig. 4b). This is consistent with the

14 Jul 2011: 2e andSupplementary Fig. 13), correlating with the requirements for ubiqui-tination (Fig. ... 4f). Ribosomessynthesizing nascent membrane proteins can recruit both the SRPand Bag6 complex on entry of the first hydrophobic segment intothe ribosomal tunnel4

9 Nov 2011: This strongly disfavors its translocation into the lumen, a requirement for sampling the type Itopology.

7 Oct 2005: 2002), different requirements for ac-cessory translocon components such as TRAM (Voigtet al., 1996) or the TRAP complex (Fons et al., 2003),and the choice of translocation pathway taken by thesubstrate ... In fact, since the signal sequences of Crtnd

11 Apr 2022: investigation of tail-anchored (TA)membrane protein insertion by the GET (guided entry of TA protein) pathway provided anunexpected insight that ultimately led to the discovery of a key EMC function. ... Although GET3and EMC2 are unrelated proteins, they

24 Aug 2011: 6 F). To test the requirement for CLIC endocytosis during mi-gration, this inactivation assay was applied to migrating fibro-blasts.

5 Dec 2012: The inhibitoryactivity of the myristoylated peptide required its entry into the cells be-cause both myristoylated and TAT-tagged peptides inhibited Gbg-dependentactivation of Akt, whereas unmodified peptide had no such ... With regard to the requirement

22 Mar 2024: LMB postgraduate students are registered for their PhD with the Postgraduate School of Life Sciences at the University of Cambridge – leading to a University of Cambridge PhD degree. ... This relationship, between the LMB and the University of Cambridge

31 Jul 2023: Search this website. Students. The LMB postgraduate students are a truly international and diverse community.

25 Sep 2013: 130081, published 7 August 20133 2013 Open Biol. Harvey T. McMahon and David M. GloverTetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, the plasma membrane and contractile ring in cytokinesis. F-BAR protein

4 Apr 2024: This is a pioneering programme within the University of Cambridge and its aim is to bring talented students to Cambridge, who might otherwise not consider postgraduate research in the Life Sciences. ... For further details, including eligibility

19 Jan 2024: To apply please contact the LMB Postgraduate office with a letter of interest and a CV:.. ... For example Cambridge Africa offers advice and funding for postgraduates from Africa applying for courses at Cambridge.