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28 Apr 2024: Functional Requirements. Having determined the assembly and subcellular organization of CreS, we next addressed the molecular determinants of CreS- dependent cell curvature generation. ... Nevertheless, correct CreS assembly is not the only functional

3 Sep 2014: chromosomal region from ETEC H10407 genome and confirmed. the NCBI entry NC_017633.1 (Figure S1 in File S1). ... The presence of LeoA within the bacterial periplasm and its. potential requirement for hetero-dimerisation with LeoBC for.

28 Sep 2012: 11.2 What is Coot? 11.3 What Coot is Not. 11.4 Hardware Requirements. ... 1.4 Hardware Requirements. The code is designed to be portable to any Unix-like operating system.

22 Jul 2008: When posi-tioned in the looped orientation, elongation of the nascent chain results in its entry into the ER lumen. ... The only requirement would be a capacity to interact, at least weakly, with specifi c regions of a nascent chain to bias its

22 Jul 2007: LTR, long terminal repeat; FLAG, antibody tag; IRES, internalribosome entry site; SP, signal peptide (the sequences shown are for the nls or memb.). ... Proc Natl Acad SciUSA 93: 6665–6670. Rangarajan A, Hong SJ, Gifford A, Weinberg RA (2004) Species-

15 Sep 2011: In an attempt to identify the upstream activator of Rac1 in IL-2R entry, we tested the role of p85α and PI 3- Kinase. ... could lead to the recruitment and/or the activation of Rac1 in the clathrin- and caveolin-independent entry used by IL-2R uptake. ==

30 Nov 2006: such diversity in sequence, efficiency, or complexity in. their requirements for additional factors. ... that acts to minimize PrP entry into and misfolding within. the ER lumen.

11 Apr 2022: investigation of tail-anchored (TA)membrane protein insertion by the GET (guided entry of TA protein) pathway provided anunexpected insight that ultimately led to the discovery of a key EMC function. ... Although GET3and EMC2 are unrelated proteins, they

16 May 2008: Further-more, enveloped viruses gain entry into the cytosol by fusing their limiting membranes with host cell membranes (FIG. ... Analogous to the requirement of HOpS for efficient vacuole fusion. in yeast, the tethering factor and rab5 effector eeA1 is

3 Nov 2001: Anders andD. Botstein, personal communication), in furtheragreement with the requirement of these residuesfor nucleotide hydrolysis. ... Initial amplitudes were obtainedfrom 94 electron diffraction patterns, which had an over-all Friedel R-factor of 19 %

9 Nov 2001: Nevertheless, becauseamphmut larvae clearly show a much milder phenotypethan that of shibirets larvae at their restrictive tempera-ture, amphiphysincannotbeanabsolute requirement forsynaptic vesicle recycling at the NMJ.The amph mutants also showed

11 Nov 1999: protein kinase Lck30 (PDB entry 3lck). c, Stereo diagram of PI3Kg active site with bound. ... Different structural requirements within the switch II region of the Ras protein for.

18 Feb 2016: In yeast, Sgt2 clients can be trans-ferred to the TRC40 homolog Get3 (guided entry of tail-anchored proteins 3) via the Get4–Get5bridging complex, with Get5 recruiting Sgt2 and Get4 ... This dual requirement wouldsharpen client discrimination by

27 Apr 2009: often artificially clustered) endogenous mark-ers or bacterial exotoxins predominantly by flu-orescence microscopy, from determining thelipid requirements for these pathways, from ex-amining their sensitivity to certain drugs, andfrom ascertaining

16 Nov 2011: insertion into the ER43. Although this and subsequent studies showed that insertion was protein and ATPdependent43–46, the molecular basis of this energy requirement and the factors involved in insertion remained ... The high level of conservation

17 Feb 2010: superposition on the DNA complex of phage 343 repressor. (PDB entry 2or1; Aggarwal et al, 1988). ... Colour code as in (B). Double-stranded DNA in grey (taken from pdb entry 2OR1).

15 Nov 2011: and gp64-mediated fusion processes are triggered bytreating HA- or gp64-expressing cells with a low pH mediumthat mimics conditions in acidified endosomes during viral entry.In these fusion processes, the

30 Jul 2013: signal much more difficult to achieve. At the time the distortion–correction method was being developed, the symmetrical, top-entry. ... tional drift-stability compared with standard side-entry cold stages, and the overall microscope.

10 Jun 2008: elegans. A thesis submitted in partial satisfaction of the. requirements for the degree Master of Science.

24 Sep 2004: The observedsubstrate inhibition by Ins(1,4,5)P3 and non-linear kinetics with ATP(data not shown) may be caused by a requirement for ATP to bindbefore

27 Mar 2012: the requirement for ZipA, which is another Z-ring membrane. anchor in E.

9 May 2003: Cameleon imaging of calcium transients in cultured mechanosensory neurons in Caenorhabditis elegans. Christian Frøkjær-Jensen Speciale. February 2003 Niels Bohr Institute. University of Copenhagen. 2. Table of contents Abstract. 3 Credit. 4

25 Apr 1997: Furthermore, because the epi-and its entry into the translocation channel, whereas a. ... Although the length of time that the nents, demonstrated the requirement for a surprisinglychain is exposed to the cytosol is brief, it is significant.

23 Sep 2011: All data are expressed as mean SEM Entries in bold are significantly different from the other conditions using a one-way ANOVA followed by Dunnett’s multiple-comparisons test (p ... J Neurosci Methods76:1–5. Sato K, Ernstrom GG, Watanabe S, Weimer RM,

19 Aug 2023: The ER also contains members of the Oxa1 superfamily of TMD insertases9, including the guided entry of tail anchored protein (GET) complex10, the ER membrane protein complex (EMC)11 and TMCO1 ... 2f and Extended Data Fig. 4b). This is consistent with the

6 Mar 2008: A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy.

2 Feb 2004: Membrane transport between compartments in eukary-otic cells requires proteins that allow the budding andSCISSION of nascent cargo vesicles from one compartmentand their targeting and fusion with another. Just asSNARES are proposed to be essential

25 Sep 2013: 130081, published 7 August 20133 2013 Open Biol. Harvey T. McMahon and David M. GloverTetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, the plasma membrane and contractile ring in cytokinesis. F-BAR protein

14 Jul 2021: Shi et al., 2020; Higashi et al., 2020) and does so in the absence of Scc3 without entry inside the. ... chore protein Ctf19, a requirement that is apparently not bypassed by smc1D588Y.

14 Jun 2007: Many plasma-membrane proteins are in a constant flux throughout the internal trafficking pathways of the cell. Some receptors, such as that for transferrin, are continuously internalized into recycling endosomes and returned to the cell surface.

9 Nov 2011: This strongly disfavors its translocation into the lumen, a requirement for sampling the type Itopology.

16 Jul 2008: Molecular Biology of the CellVol. 19, 3463–3476, August 2008. Retrotranslocation of Prion Proteins from the EndoplasmicReticulum by Preventing GPI Signal TransamidationAarthi Ashok and Ramanujan S. Hegde. Cell Biology and Metabolism Program,

7 Oct 2005: 2002), different requirements for ac-cessory translocon components such as TRAM (Voigtet al., 1996) or the TRAP complex (Fons et al., 2003),and the choice of translocation pathway taken by thesubstrate ... In fact, since the signal sequences of Crtnd

14 Jul 2011: 2e andSupplementary Fig. 13), correlating with the requirements for ubiqui-tination (Fig. ... 4f). Ribosomessynthesizing nascent membrane proteins can recruit both the SRPand Bag6 complex on entry of the first hydrophobic segment intothe ribosomal tunnel4

24 Aug 2011: 6 F). To test the requirement for CLIC endocytosis during mi-gration, this inactivation assay was applied to migrating fibro-blasts.

5 Dec 2012: The inhibitoryactivity of the myristoylated peptide required its entry into the cells be-cause both myristoylated and TAT-tagged peptides inhibited Gbg-dependentactivation of Akt, whereas unmodified peptide had no such ... With regard to the requirement

14 Dec 2010: Caenorhabditis Elegans. A dissertation submitted in partial satisfaction of the. requirements for the degree Doctor of Philosophy. ... entry’ to the UK for five months. Dr. Arnivan Ghosh for his ability as a committee.