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Filament structure and subcellular organization of the bacterial…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Liu_PNAS_crescentin_2024.pdf28 Apr 2024: Functional Requirements. Having determined the assembly and subcellular organization of CreS, we next addressed the molecular determinants of CreS- dependent cell curvature generation. ... Nevertheless, correct CreS assembly is not the only functional -
pone.0107211 1..10
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/leoa2014.pdf3 Sep 2014: chromosomal region from ETEC H10407 genome and confirmed. the NCBI entry NC_017633.1 (Figure S1 in File S1). ... The presence of LeoA within the bacterial periplasm and its. potential requirement for hetero-dimerisation with LeoBC for. -
coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: 11.2 What is Coot? 11.3 What Coot is Not. 11.4 Hardware Requirements. ... 1.4 Hardware Requirements. The code is designed to be portable to any Unix-like operating system. -
TH EJ OU RN AL OF CE LL BIO ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/53_Hegde_RS_JCB_2008.pdf22 Jul 2008: When posi-tioned in the looped orientation, elongation of the nascent chain results in its entry into the ER lumen. ... The only requirement would be a capacity to interact, at least weakly, with specifi c regions of a nascent chain to bias its -
Tumour prevention by a single antibody domaintargeting the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17568777.pdf22 Jul 2007: LTR, long terminal repeat; FLAG, antibody tag; IRES, internalribosome entry site; SP, signal peptide (the sequences shown are for the nls or memb.). ... Proc Natl Acad SciUSA 93: 6665–6670. Rangarajan A, Hong SJ, Gifford A, Weinberg RA (2004) Species- -
Abstract_Book_HMM_v2
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/JM_Abstract_Book.pdf15 Sep 2011: In an attempt to identify the upstream activator of Rac1 in IL-2R entry, we tested the role of p85α and PI 3- Kinase. ... could lead to the recruitment and/or the activation of Rac1 in the clathrin- and caveolin-independent entry used by IL-2R uptake. == -
doi:10.1016/j.cell.2006.10.032
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/43_Kang_SW_Cell_2006.pdf30 Nov 2006: such diversity in sequence, efficiency, or complexity in. their requirements for additional factors. ... that acts to minimize PrP entry into and misfolding within. the ER lumen. -
The Function, Structure, and Origins of the ER Membrane Protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Annual_Rev_Biochem_2022.pdf11 Apr 2022: investigation of tail-anchored (TA)membrane protein insertion by the GET (guided entry of TA protein) pathway provided anunexpected insight that ultimately led to the discovery of a key EMC function. ... Although GET3and EMC2 are unrelated proteins, they -
Membrane fusion is the process whereby two separate lipid ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensMcMahon2008.pdf16 May 2008: Further-more, enveloped viruses gain entry into the cytosol by fusing their limiting membranes with host cell membranes (FIG. ... Analogous to the requirement of HOpS for efficient vacuole fusion. in yeast, the tethering factor and rab5 effector eeA1 is -
Refined Structure of (alpha)(beta)-Tubulin at 3.5 A Resolution
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/jmb%20tubulin%20refinement.pdf3 Nov 2001: Anders andD. Botstein, personal communication), in furtheragreement with the requirement of these residuesfor nucleotide hydrolysis. ... Initial amplitudes were obtainedfrom 94 electron diffraction patterns, which had an over-all Friedel R-factor of 19 % -
Amphiphysin is necessaryfor organization of the…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DroxAmph.pdf9 Nov 2001: Nevertheless, becauseamphmut larvae clearly show a much milder phenotypethan that of shibirets larvae at their restrictive tempera-ture, amphiphysincannotbeanabsolute requirement forsynaptic vesicle recycling at the NMJ.The amph mutants also showed -
N402_18f 313..320
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10580505.pdf11 Nov 1999: protein kinase Lck30 (PDB entry 3lck). c, Stereo diagram of PI3Kg active site with bound. ... Different structural requirements within the switch II region of the Ras protein for. -
Target Selection during Protein Quality Control
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/96_Shao_S_TIBS_2016.pdf18 Feb 2016: In yeast, Sgt2 clients can be trans-ferred to the TRC40 homolog Get3 (guided entry of tail-anchored proteins 3) via the Get4–Get5bridging complex, with Get5 recruiting Sgt2 and Get4 ... This dual requirement wouldsharpen client discrimination by -
ANRV378-BI78-31.tex
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiochem09.pdf27 Apr 2009: often artificially clustered) endogenous mark-ers or bacterial exotoxins predominantly by flu-orescence microscopy, from determining thelipid requirements for these pathways, from ex-amining their sensitivity to certain drugs, andfrom ascertaining -
Tail-anchored membrane protein insertion into the endoplasmic…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/77_Hegde_RS_NRMCB_2011.pdf16 Nov 2011: insertion into the ER43. Although this and subsequent studies showed that insertion was protein and ATPdependent43–46, the molecular basis of this energy requirement and the factors involved in insertion remained ... The high level of conservation -
Bacterial actin MreB assembles in complex with cell shape protein RodZ
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf17 Feb 2010: superposition on the DNA complex of phage 343 repressor. (PDB entry 2or1; Aggarwal et al, 1988). ... Colour code as in (B). Double-stranded DNA in grey (taken from pdb entry 2OR1). -
Biochem. J. (2011) 440, 185–193 (Printed in Great Britain) ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/ChernomordikBJ2011.pdf15 Nov 2011: and gp64-mediated fusion processes are triggered bytreating HA- or gp64-expressing cells with a low pH mediumthat mimics conditions in acidified endosomes during viral entry.In these fusion processes, the -
Qrb1300006 1..40
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf30 Jul 2013: signal much more difficult to achieve. At the time the distortion–correction method was being developed, the symmetrical, top-entry. ... tional drift-stability compared with standard side-entry cold stages, and the overall microscope. -
Thesis Chapter 0
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/Hardaker.pdf10 Jun 2008: elegans. A thesis submitted in partial satisfaction of the. requirements for the degree Master of Science. -
doi:10.1016/j.molcel.2004.08.004
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15350214.pdf24 Sep 2004: The observedsubstrate inhibition by Ins(1,4,5)P3 and non-linear kinetics with ATP(data not shown) may be caused by a requirement for ATP to bindbefore
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