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www-jackson.ch.cam.ac.uk/publications/2003/2003_Biochem.pdf11 Sep 2003: Wang et al., 2000);barstar (Schreiber et al., 1994); and p53 (Nikolova et al.,1998). ... P., and Fersht, A. R. (1998)Semirational Design of Active Tumor Suppressor p53 DNABinding Domain with Enhanced Stability,Proc. -
doi:10.1016/S0959-440X(03)00105-2
www-jackson.ch.cam.ac.uk/publications/2003/2003_COSB_main.pdf16 Sep 2003: In related work, reminiscentof p53 rescue [25], Cammett et al. [15] showed that thedeleterious effect of the oncogenic mutations could bereversed by designing secondary stabilizing mutationselsewhere in the protein. ... Protein Sci 2001,10:2123-2130. 25. -
doi:10.1016/j.jmb.2007.06.065
www-jackson.ch.cam.ac.uk/publications/2007/2007_J_mol_biol_Hsp90_inhibition.pdf8 Feb 2008: 288 Hsp90 Inhibition by Ansamycin Derivatives. as mutated p53, Akt, Bcr-Abl, and ErbB2.7 Two GAderivatives, 17-allylamino,17-demethoxygeldana-mycin (17-AAG) and the water-soluble 17-dimethyl-. -
doi:10.1016/j.jmb.2004.09.055
www-jackson.ch.cam.ac.uk/publications/2004/2004_JMB_McLaughlin_Hsp90.pdf6 Jan 2005: This could facilitate Hsp90’s function asa matchmaker for assembly by binding multipleclient proteins such as p53 and mdm245 or eNOSand PKB/Akt.46 Thus, without the conformationalrestriction linking the -
Structures and folding pathways of topologically knotted proteins
www-jackson.ch.cam.ac.uk/publications/2010/2010_J_Phys_Conds_Matt_Knotted_review.pdf21 Feb 2011: Structures and folding pathways of topologically knotted proteins. This article has been downloaded from IOPscience. Please scroll down to see the full text article. 2011 J. Phys.: Condens. Matter 23 033101.
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