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search results for p53 |u:www.immunology.cam.ac.uk
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Dr Pentao Liu | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some -
https://www.immunology.cam.ac.uk/taxonomy/term/77/feed
https://www.immunology.cam.ac.uk/taxonomy/term/77/feed23 Feb 2024: Tweddle DA.<br /> p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma.<br /> Cancer Res. -
Professor Margaret Ashcroft | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell -
Dr El Kahina Meziane | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/ekm29%40cam.ac.uk23 Feb 2024: Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis. -
Dr Rémi B. Fiancette | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/fiancette23 Feb 2024: and Denizot Y., 2012, Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. ... Magnone V., Cogné M. and Denizot Y., 2011, A p53 defect sensitizes -
Dr Andrew McKenzie | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/anm%40mrc-lmb.cam.ac.uk23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q. –. -
Dr Nunzio Iraci | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/dr-nunzio-iraci23 Feb 2024: p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma. Cancer Res. -
Dr Suzanne Dawn Turner | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/sdturner23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Merkel, O., Morrigl, R.,Turner, S.D. and Kenner, L. (2017) When the -
https://www.immunology.cam.ac.uk/taxonomy/term/59/feed
https://www.immunology.cam.ac.uk/taxonomy/term/59/feed23 Feb 2024: Cambridge Immunology Network - MRC Laboratory of Molecular Biology https://www.immunology.cam.ac.uk/departments/mrc-lmb en Conor O'Donovan https://www.immunology.cam.ac.uk/staff/conor-odonovan <div class="field field-name-field-sd-consultancy -
https://www.immunology.cam.ac.uk/taxonomy/term/7/feed
https://www.immunology.cam.ac.uk/taxonomy/term/7/feed23 Feb 2024: Cambridge Immunology Network - Autoimmunity and inflammation https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/autoimmunity-inflammation Investigating the causes of excessive and aberrant immune responses which result in inflammation -
https://www.immunology.cam.ac.uk/taxonomy/term/13/feed
https://www.immunology.cam.ac.uk/taxonomy/term/13/feed23 Feb 2024: Cambridge Immunology Network - Molecular and structural immunology https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/molecular-structural-immunology Molecular and structural techniques are used to address a wide range of -
https://www.immunology.cam.ac.uk/taxonomy/term/57/feed
https://www.immunology.cam.ac.uk/taxonomy/term/57/feed23 Feb 2024: Cambridge Immunology Network - Department of Medicine https://www.immunology.cam.ac.uk/departments/medicine en Professor Ravindra Gupta https://www.immunology.cam.ac.uk/staff/professor-ravindra-gupta <div class="field field-name-field-sd-consultancy -
https://www.immunology.cam.ac.uk/taxonomy/term/44/feed
https://www.immunology.cam.ac.uk/taxonomy/term/44/feed23 Feb 2024: Tweddle DA.<br /> p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma.<br /> Cancer Res. -
https://www.immunology.cam.ac.uk/taxonomy/term/25/feed
https://www.immunology.cam.ac.uk/taxonomy/term/25/feed23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q<sup>–</sup> syndrome.
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