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Cancer and its microenvironment! From mechanisms to translation…
https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf30 Apr 2024: We are following this research field closely and will replace animal research where we can as new technologies develop and are tested and established. ... We also discuss with other groups doing similar research and have an open policy whereby new -
Interventions in pregnancy effects of obesity on maternal and…
https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf30 Apr 2024: Furthermore, we have an extensive tissue bank of samples that can be utilised prior to generating new animal cohorts. ... Our group will attend termly facility user committee meetings where new information is disseminated. -
Environmental and placental contributions to pregnancy and life-long…
https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf29 Apr 2024: activities including publications in magazines, news articles, blogs, and via twitter / social media feeds. ... We will perform pilot experiments, for e.g. to check the effectiveness of new therapies. -
Extrinsic regulation of haematopoietic stem and progenitor cells in…
https://www.ubs.admin.cam.ac.uk/system/files/public/extrinsic_regulation_of_haematopoietic_stem_and_progenitor_cells_in_health_disease_and_as_a_therape_1_redacted.pdf30 Apr 2024: However, the underlying reasons (which could offer new therapies) are only partially understood. ... might be doing regarding animal research and ensure our methods stay updated within the new refinements implemented by others. -
Generation and screening of companion animal therapeutics.…
https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf30 Apr 2024: Monoclonal antibodies are expected to become a new standard of care in veterinary medicine. ... In order to predict protein structures and design new proteins, large language models (LLMs) are used. -
CNS Neuron-glia interactions, myelin plasticity, and regeneration, in …
https://www.ubs.admin.cam.ac.uk/system/files/public/cns_neuron-glia_interactions_myelin_plasticity_and_regeneration_in_health_and_disease_non-techni_redacted.pdf30 Apr 2024: The outputs of this licence will likely result in a new information and publications of the following:. ... With this knowledge gained we can identify new testable pathways for augmenting regeneration. -
Biobehavioural basis of the individual vunerability to impulsive…
https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_the_individual_vulnerability_to_impulsivecompulsive_spectrum_disorders_redacted.pdf29 Apr 2024: Similarly, it would not be possible to develop new treatments for brain disorders without testing them in animal models first. ... Any new procedure, or combination of procedures, used under this project licence will systematically be previously -
Neural, physiological and behavioural mechanisms underlying cognition …
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf30 Apr 2024: We have chosen to work with a new world monkey, the common marmoset. ... When we embark on a new study we tend to start off with 2 lead animals in which we test out our hypothesis. -
Neuronal circuit mechanisms underlying cognitive memory judgements…
https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf30 Apr 2024: memory symptoms, guiding new treatment strategies as well as providing insight into the mechanisms by which current therapies have their efficacious actions. ... When I embark on a new study, I start off with 2 lead animals in.
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