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13 Oct 2016: Search this website. New drug target for asthma. New drug target for asthma. ... Published on. 13 October, 2016. A new therapeutic target for inflammatory diseases such as asthma and autoimmune disorders has been identified by scientists at the Wellcome

20 Jul 2016: 20 July, 2016. Researchers in Greg Jefferis’s group in the LMB’s Neurobiology Division have developed a new online tool to analyse images of neurons. ... NBLAST is already proving useful in fly brain research to identify neuron types, organize large

14 Dec 2016: New hypothesis for the formation of macropinocytic cups. Published on. 14 December, 2016. ... the USA and Robert Insall at the Beatson Institute in Glasgow, has resulted in the formation of a new hypothesis for how these cups form.

13 Dec 2016: Search this website. New microscope lens: top ten breakthroughs. New microscope lens: top ten breakthroughs. ... Ten Breakthroughs of 2016, for creating a new microscope lens that offers the unique combination of a large field of view with high resolution

2 Sep 2016: Thus parental H3/4 tetramers are interspersed with newly synthesised H3/4. Most of the time, the old and new proteins are not mixed within the same nucleosome. ... In DT40 cells lacking Rev1, certain normally repressed genes containing G quadruplex DNA

11 Jul 2016: LMB welcomes Joseph Yeeles as new Group Leader. Published on. 11 July, 2016. ... Our development of a reconstituted eukaryotic replication system provides exciting new opportunities to investigate mechanisms of chromosome replication in ways that were

13 Oct 2016: This has given unprecedented insight into the catalytic mechanism of a DUB and revealed a new mechanism of how ubiquitin chains can be cleaved. ... The new understanding of the catalytic process in deubiquitinases will become a key reference point for

17 Nov 2016: Search this website. LMB welcomes Emmanuel Derivery as new Group Leader. ... LMB welcomes Emmanuel Derivery as new Group Leader. Published on. 17 November, 2016.

24 Oct 2016: Search this website. New technologies enable systematic recoding of genomes. New technologies enable systematic recoding of genomes. ... Using these new techniques they attempted systematic recoding of the genomic sequence in an essential operon using

12 Apr 2016: Search this website. Artificial DNA could build new generation of cancer drugs. ... Artificial DNA could build new generation of cancer drugs. Published on.

1 Feb 2016: Search this website. Cryo-EM sheds new light on the spliceosome activation process. ... Cryo-EM sheds new light on the spliceosome activation process. Published on.

11 Feb 2016: Structural insight offers potential for new anti-malarial treatment. Published on. 11 February, 2016. . ... falciparum proteasome and used this information to design a new compound with promising anti-malarial properties.

9 Mar 2016: She is also developing new methods with cryo-EM to help determine protein structure, including the development of new specimen grids made of pure gold, that improve the quality of

8 Dec 2016: Now researchers in the LMB’s Structural Studies and Cell Biology divisions have used electron cryomicroscopy (cryo-EM) to reveal new insights into these mechanisms. ... It is hoped that these new insights will enrich our understanding of the

29 Mar 2016: LMB, on a journey to cast surprising new light on the universal cellular ubiquitin modification system (page 9) More….

26 Jul 2016: This has provided important mechanistic insights into RNA-based splicing catalysis. It has consolidated nearly three decades of biochemistry and genetics on the spliceosome and indicates new research directions to be

16 Jun 2016: Published on. 16 June, 2016. Details of the Soft Landings project for the new LMB building, including a summary of the building’s special features, the design and construction process and

27 Jun 2016: The winner of the Copley Medal talks structural biology, fixing cars and sleeping soundly. More...

6 Jul 2016: The LMB’s Danielle Mersch and Nicola Smyllie along with other leading female scientists from the region took to their soapboxes on Saturday 2nd July in

13 Jun 2016: Richard Treisman, biochemist, molecular biologist and Research Director at the Francis Crick Institute, has been knighted in the Queen's Birthday Honours

17 Feb 2016: How advances in neuroscience, including LMB's Madeline Lancaster's work on 'mini-brains', are helping to unlock the secrets of this biological masterpiece

19 Dec 2016: area. The planting of the trees will provide a unique linear orchard that marks the routes between the new developments south of the city and the city centre.

2 Feb 2016: Published on. 2 February, 2016. Cambridge News’ has been rounding up all of Cambridge’s 92 Nobel Laureates, which includes 15 LMB scientists: 13 whose Nobel Prize winning research was conducted ... These articles are no longer available from the

6 Oct 2016: A custom-built objective lens called the Mesolens allows relatively large biological specimens to be imaged with cellular resolution. It was developed by

19 Dec 2016: Medical Daily includes work by the LMB's Leo James's group and University College London on improving antiviral drugs as one of its HIV research

7 Jul 2016: Published on. 7 July, 2016. LMB Group Leader, Greg Jefferis, has been elected as one of 15 new FENS Kavli Scholars.

24 May 2016: Two former LMB group leaders have been named as new EMBO members. ... Jernej and Ian are among 58 new members to join EMBO, who elect new members annually on the basis of scientific excellence and outstanding research contributions.

1 Dec 2016: The LMB has continued its collaboration with the University Technical College Cambridge (UTCC), with students visiting as part of their microscopy

10 Mar 2016: Venki talks about his life and work for BBC Radio 4's The Life Scientific. More...

29 Jan 2016: How to combine biology, chemistry and synthetic biology to add synthetic amino acids to a protein, and why creativity matters. Profile of LMB group

30 Jun 2016: Published on. 30 June, 2016. Melina Schuh, former Group Leader in the LMB’s Cell Biology Division, will deliver her Lister Prize lecture, “New insights into aneuploidy in human oocytes”, on

7 Nov 2016: It gave me a new perspective to our work in the lab and I’m looking forward to next time!”.

4 Jan 2016: The new structure provides the first high resolution view of an open and functioning protein conducting channel. ... By comparing the new Sec61 structure to these previous structures, they have predicted a two-step mechanism for how the channel might be

23 Nov 2016: group working on new tissue culture methods.

17 Nov 2016: Sabine Petry, LMB 2003-2007, PhD Student, Structural Studies Originally from Germany, Sabine received her Diploma (MSc) from Goethe University and

22 Nov 2016: Monoclonal antibodies now account for a third of all new treatments and provide therapy for a diverse array of diseases from breast cancer to arthritis.

6 Sep 2016: Published on. 6 September, 2016. The ability of scientists to create changes in gene sequences has improved dramatically in recent years with the emergence of a new method, dubbed ‘CRISPR’. ... This new approach was inspired by work in rice, which

6 Dec 2016: Bicycle is pioneering a new class of drugs based on its bicyclic peptide platform, and will be working with AZ to spot and develop new treatments for respiratory, cardiovascular and metabolic

25 Oct 2016: Profile of LMB group leader Katja Röper and her work on how cytoskeletal behaviour controls tissue morphogenesis. More...

19 Dec 2016: Over £1500 has been raised by LMB staff for The British Heart Foundation (BHF) at the annual charity Christmas raffle. The BHF was chosen in memory of

26 May 2016: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures

13 Apr 2016: Heptares Therapeutics, an LMB spin-out company, announces a deal with Allergan for development of novel treatments for neurological disorders, including

19 Oct 2016: For the second year running, the LMB’s HR team, supported by colleagues across the LMB, showed off their baking skills for the Macmillan Cancer Support

18 Mar 2016: 'Synthetic biology' is a scientific approach that seeks to answer fundamental questions in biology by reconstruction and modification of the molecules and

29 Apr 2016: Each year, the Royal Society elects up to 52 new Fellows and up to ten new Foreign Members, recognising those scientists who have made substantial contributions to the improvement of knowledge

11 Mar 2016: In addition, AMPA receptors are drug targets and the new structure offers development to novel protein interfaces of the receptor.

25 Oct 2016: The LMB has continued its winning cycling record by taking first place in its category in the Love to Ride Cambridgeshire event – part of the National

3 May 2016: Christos Savva, Electron Microscopy Facility scientist at the LMB, talks about why understanding structures of important proteins could be the key to

23 Mar 2016: As part of the Cambridge Science Festival, two of the LMB’s group leaders talked to the public about their research at the University Technical College

26 Aug 2016: Over the past 3 years the LMB has, as part of a Government initiative to provide three million new apprenticeships by 2020, supported two MRC apprentices in the Mechanical and Electronics