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26 Aug 2005: University, 266 Whitney Avenue, New Haven, CT. 06520, USA. e-mail: lynne.regan@yale.edu. ... of functionand new interactions between the polyglutamine repeatand other cellular proteins that are not normally htt-binding partners, thereby altering their

6 Jan 2005: Several reports on new cochaperones demonstrated the complexity and versatility of the Hsp90 machine. ... Mutation screens and transgenic models have added new Hsp90 clients and shed light on cochaperone function in vivo.

26 Aug 2005: New Haven, CT 06520, USA7 Department of Chemistry, Yale University, 266 Whitney Avenue, New. ... 32. Nelson P: Biological Physics: Energy, Information, Life. New York:WH Freeman; 2003.

17 Jul 2005: New York: Freeman. Cui, Q., Li, G., Ma, J. & Karplus, M.

17 Jul 2005: Jackson‡, and Lynne Regan†. Departments of †Molecular Biophysics and Biochemistry and Chemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520; ‡Cambridge UniversityChemical Laboratory, University of Cambridge, Lensfield Road,

6 Jan 2005: To unravel these contradictions, we havedissected the kinetic mechanism of human Hsp90ATPase activity to reveal the dynamics of theindividual steps in binding and hydrolysis, leadingus to propose a new model of ... Our resultssuggest a new model for the

19 Apr 2005: 9JT, United Kingdom9Department of Biochemistry, Umea University, S-901 87 Umea, Sweden10Department of Chemistry, State University of New York, Stony Brook, New York 11794, USA11Département de Biochimie, Université de Montréal, Montréal,

17 Jul 2005: the above similarities betweenMTases with knotted structures, a new class offold has been defined known as the SPOUT (SpoU-TrmD) class MTase fold.3 Features of MTasesbelonging to the SPOUT class