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7 Dec 2022: o The generation of new lines o Transferring animals from Protocol 1 to other Project Licences if they look to exceed the.

14 May 2024: The committee were pleased to see refinements previously developed with collaborators being brought forward into this new licence. •

7 Dec 2022: Project Licences (a) New licence: ( was also in attendance) The committee discussed the following:. • ... Page 3 of 3. • Further information around whether new histological techniques have been published in Section 3.Further information regarding the

7 Dec 2022: b) New Licence: The committee discussed the following:. • Clarify in Protocols how diarrhoea will be used as a measure. • ... Since some animals lose weight after the surgery undertaken in the new, the committee suggested introducing the animals to

7 Dec 2022: b) Amendment: The committee discussed the following:. • Change experience from PILC to PIL F.• Amend error in the new text in the Project Plan• Suggest changing the text in Protocol Adverse

11 Jan 2023: suggested putting an FOI link on the website, agreed. said there are a lot of new project licence applications on ASPeL. ... concerns. The HO are not going to issue any guidance on the use of new ASPeL.

7 Dec 2022: Project Licences (a) New licence: The committee discussed the following:. • Suggest further information about the attrition rate of the different organs and why and who determines organs are not suitable for ... 6. Matters arising from the minutes and

7 Dec 2022: A new page will be created on the UBS website and these will be uploaded to this. ... Page 3 of 3. informed the committee that has made a request for a bridging licence because his current licence is due to run out before his new licence is granted.

28 Nov 2023: Project Licences (a) New licence: were also in attendance) The committee discussed the following:. • ... The importance of communication the new Licence Holder must have with the animal facility staff on a day to day basis, that they will be

7 Dec 2022: Page 2 of 3. (b) New Licence: The committee discussed the following:. • ... c) New Licence: (Attending on his behalf: ) The committee discussed the following:. •

28 Nov 2023: Consideration given to whether the new objective 6 should apply to Protocols 5 and 6. •

7 Mar 2023: Further clarification in regards to which part of the new funding relates to the increase in animal numbers.

7 Dec 2022: The recommendation that any PIL holders new to the facility visit the for an induction to the facilities ahead of any planned surgery. ... b) New Licence: The committee discussed the following:. • Re-writing required in regards to the scientific words

7 Dec 2022: It was recognised that the work is. carrying on under new PPL The committee also commended outreach and publications, considering the animal numbers and usage of this licence. •

7 Mar 2023: The recommendation that the researcher checks whether new limits should be included in the humane endpoint section in regards to step 2 of Protocol 9.

7 Dec 2022: Apologies: MINUTES 1. Project Licences. a) New: The committee discussed the following:. •

7 Dec 2022: Page 2 of 3. (c) New: The committee discussed the following:. •

5 Jul 2023: 1d) Apologies: Minutes: 1. Project Licences (a) New licence: was also in attendance) The committee discussed the following:. • ... c) New Licence: The committee discussed the following:. • The recommendation that the applicant reviews the

7 Dec 2022: Project Licences (a) New licence: was also in attendance) The committee discussed the following:. • ... c) New Licence: ( ) The committee discussed the following:. • The recommendation that the answers provided during the AWERB meeting around when

28 Feb 2020: We realise that we must not be complacent and therefore will actively promote, investigate and use new methods of research that can replace animals and only ever use animals where these

7 Dec 2022: Further consideration given to new lines and expected adverse effects to ensure the licence is not.

7 Dec 2022: receive prior to taking over the Licence. • The recommendation that if there is any intention to hold animals on the Licence before the new.

7 Dec 2022: Project Licences (a) New licence: The committee discussed the following:. • Further justification required in the Aims section of the application. • ... b) New Licence: The committee discussed the following:. • Further consideration given in the

7 Mar 2023: Project Licences (a) New Licence: attended on his behalf) The committee discussed the following:. • ... b) New Licence: The committee discussed the following:. • Further explanation of technical language used in the Non-Technical Summary. •

7 Dec 2022: The committee agreed changes were needed before a draft application is submitted to the Home Office (b) New Licence: The committee discussed the following:. • ... The committee agreed changes needed to be made before a draft application is submitted to

7 Mar 2023: Project Licences (a) New licence: The committee discussed the following:. • The removal of the by name from the Non-Technical Summary. • ... c) New Licence: The committee discussed the following:. • Further justification required in regards to

26 Sep 2012: What are the new units called and how do they compare with existing modules? ... Laboratory animal physiology R/602/6048 3 12. What are the new units?

20 Aug 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

19 Aug 2021: Understanding the mechanisms that control killing by these cells will improve the design of new immunotherapies. ... We will provide new information on pathways that are required by killer cells of the immune system.

13 Sep 2021: Longer-term benefits will be opportunities for making new treatments for controlling fertility in humans.

13 Sep 2021: The work will identify exactly how aneurysms develop and new treatments to prevent this. ... culture. Some aspects of disease including assessment of new treatments still require animal studies.

13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every ... Our study aims to: 1) Increase the understanding of how types of breast and lung cancers

18 Aug 2015: 16. Slide 16: Why replace animals? - Scientific advantages: New technology can be exploited. ... The development of new technologies opens up opportunities for expanding or improvingresearch in a variety of ways.

19 Aug 2021: It also allows for the initial testing of new treatment compounds to assess their compatibility. ... This enables the brain to make new circuits to bypass the damaged neurons.

30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... As we have shown, when a new 3Rs method becomes available (e.g., hiPSC-derived neurons), we

29 Apr 2024: What's the aim of this project? The overall aim of the research is to develop new and improved vaccines. ... New vaccines need to be safe, well tolerated, effective and offer broad coverage against many pathogens.

30 Apr 2024: Human embryos are highly inaccessible for research. We use animals to test new experimental approaches, and the knowledge gained can be used to investigate similar events in precious human fetuses and ... We have reduced significantly the number of mice

20 Aug 2021: Work from this licence is likely to unravel new ways to manipulate the behaviour of these cells and inflammatory responses therapeutically. ... The key aspect of our programme is to visualise neutrophil behaviours in situ by advanced microscopy techniques

13 Sep 2021: However, we sometimes need to breed mice carrying particular genetic modifications to provide early embryos for short-term experiments or to generate new stem cell lines. ... Page 4 of 4. means that we require fewer embryo recipient females for creating

30 Apr 2024: Our findings will help both clinical and basic science research in reproductive biology and epigenetics to generate new research questions. ... Culture methods for human placental trophoblast cells are very new and still under development.

29 Apr 2024: Animals will be brought in and allowed to acclimatise for a few weeks - this helps them to relax in their new surroundings, gets them used to the staff and human contact ... bones, which acts as a shock absorber), to which the new implant/therapy will be

13 Sep 2021: What's the aim of this project? After food consumption the gut sends signals to the rest of the body preparing it for the arrival of new nutrients. ... We constantly review the literature whilst planning our experiments and acclimatize animals to new

20 Aug 2021: There is a pressing clinical need to identify new types of treatment for human disease (for example, the development of novel antibiotics) and engineered antibodies have considerable potential for this.

13 Sep 2021: Our research will study how and where the bacteria hide in the body to resist to vaccines and antibiotics and will test new innovative vaccines. ... impact of medical treatments and new vaccines on the behaviour of bacteria in an environment that closely

30 Apr 2024: In work under this licence we aim to identify new treatments for CKD, AKI and NAFLD. ... project? We hope to optimise new imaging efficacy endpoints that will allow assessment of animals over time.

13 Sep 2021: Although stem cells in the brain can make new oligodendrocytes that restore myelin, this regenerative process declines with age. ... Our discoveries may be harnessed to develop new regenerative therapies in the treatment of MS.

18 Jun 2021: This may be in the form of a new vaccine strategy, or a new anti-viral drug. ... Furthermore, to determine how effective new vaccine approaches are, experimental infections in mice are required.

30 Apr 2024: For each stock a new generation will be grown every 18 months (3.3 generations per line in 5 years). ... For each we will breed a new generation every 18 months (2560x3.3=8448).

13 Sep 2021: Our research aims to understand the bases of these disorders, and develop new treatments for them. ... We also aim to use these models to develop new and better treatments for mental health disorders.

25 Sep 2015: whilst recognising the need to use animals in biomedical research, the development of new medicines. ... welfare. The Home Office Inspectorate is responsible for:.  Processing applications for new licences and certificates.