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18 Jun 2021: This may be in the form of a new vaccine strategy, or a new anti-viral drug. ... Furthermore, to determine how effective new vaccine approaches are, experimental infections in mice are required.

13 Sep 2021: What's the aim of this project? After food consumption the gut sends signals to the rest of the body preparing it for the arrival of new nutrients. ... We constantly review the literature whilst planning our experiments and acclimatize animals to new

25 Sep 2015: whilst recognising the need to use animals in biomedical research, the development of new medicines. ... welfare. The Home Office Inspectorate is responsible for:.  Processing applications for new licences and certificates.

13 Sep 2021: Our research aims to understand the bases of these disorders, and develop new treatments for them. ... We also aim to use these models to develop new and better treatments for mental health disorders.

20 Aug 2021: Given how little innovation there is in veterinary medicine (compared to human medicine), this new class of drugs could have an even bigger impact on pet health than it did on ... In summary: Short-term benefit – New veterinary medicines based on what

20 Aug 2021: There is a pressing clinical need to identify new types of treatment for human disease (for example, the development of novel antibiotics) and engineered antibodies have considerable potential for this.

8 Jan 2015: The funding bodies encourage researchers to look for opportunities for developing new 3Rs techniques as part of larger programmes of work. ... 21. Communication of advances in the 3RsResearchers should ensure that any new procedures or improvements in

30 Apr 2024: 1. New mouse models of mitochondrial disease which carry mutations similar to those found in humans. ... The remaining 20% will be neonates (new born pups up to weaning - approx.

13 Sep 2021: Our research will study how and where the bacteria hide in the body to resist to vaccines and antibiotics and will test new innovative vaccines. ... impact of medical treatments and new vaccines on the behaviour of bacteria in an environment that closely

30 Apr 2024: For example, understanding how cell identity can contribute to diseases may help in the discovery of new treatments. ... I am currently on the European Xenopus Resource Steering Committee where new developments in frog husbandry are often discussed.

13 Sep 2021: The plan is to generate approximately 10 new models over the course of the licence. ... In this licence we will use lung tumour models to investigate new potential drugs for the treatment of lung cancer.

30 Apr 2024: 6.1 million deaths annually (https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death). ... This is confounded by the fact that there have been very few new antimicrobial products that have been developed over the last 15 years.

30 Apr 2024: We will make a new generation for each line every year (5 generations per line). ... In addition, when generating new genetically modified lines, the F0 embryos need to be genotypically screened.

13 Sep 2021: For colorectal endoscopic courses, procedures may include a range of new surgical bowel procedures. ... For upper GI endoscopic courses procedures may include tonsillectomy, oesophageal, stomach, duodenal or pancreatic surgery, or other new appropriate

13 Sep 2021: To develop new drugs, it is first necessary to better understand how the nervous system works and what goes wrong in disease: enhanced understanding of how neurones work in health and ... With enhanced knowledge, our work will aid the development of new

19 Aug 2021: The treatments that come out of the project may be new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

19 Aug 2021: With all this information, new clinical trials can be designed that eventually may change clinical practice. ... They are also required by regulatory authorities before any trials of new drugs can be tested in humans.

30 Apr 2024: To the wider pharmaceutical industry and patients this could lead into the development of new anti-cancer therapies. ... Pilot studies are used to establish the correct dose of reagents/cells, timelines, and to generate baseline data for new experiments.

19 Aug 2021: for pilot studies (https://www.nc3rs.org.uk/conducting-pilot-study);. ARRIVE guidelines, https://www.nc3rs.org.uk/arrive-guidelines;. IMPROVE guidelines for stroke models: ... I receive regular updates via the Biological Service of the University of

29 Apr 2024: This could lead to development of new therapies that are more effective and cause fewer side effects to patients. ... More specifically, we expect to generate at least one new therapy and advance it to a stage that it can be investigated further in large