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  2. AOC Minutes 20th October 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_201023_redacted.pdf
    14 May 2024: It was agreed she could stay for longer. A new permanent grade 3, has been appointed in. ... We have a new UBS Senior HR Coordinator who started three weeks ago.
  3. AOC Minutes 20th November 2020

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_20.11.20_redacted.pdf
    14 May 2024: 4. NACWO Reports None 5. Director and Deputy Director Reports. noted that he’d like to update the set of interview questions UBS hold and asked for new questions to be ... After the first 200 project licences have been put through the new ASPeL system
  4. AWERB Standing Minutes 24th January 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_240124_redacted.pdf
    30 Apr 2024: 1. Project Licences (a) New licence - ( was also in attendance) The committee discussed the following:. • ... b) Amendment - The committee discussed the following:. • Inclusion of any benefits that will be gained from this amendment that will balance
  5. AWERB 3Rs Minutes 4th May 2022 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_040522_redacted.pdf
    14 May 2024: 6. Severe Severity licence reviews. 7. Standard condition 18 reports 18 new SC 18 reports submitted since last AWERB 3Rs meeting – [x6 ; x2 reporting mis-dosing via oral gavage] [x GA ... This promotes the building of new networks to achieve certain
  6. AWERB 3Rs Minutes 5th April 2023 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_050423_redacted.pdf
    14 May 2024: Further details of what this then means for the numbers that will be used under the new project licence. •
  7. AOC Minutes 24th July 2020

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_24.07.20_redacted.pdf
    14 May 2024: thanked those who have undertaken the requested process for having new staff posts advertised.
  8. AOC Minutes 18th December 2020

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_18.12.20_redacted.pdf
    14 May 2024: She asked for the. Personal Licence documents on the website to not be used until they have been updated in the New Year. ... The licencing team should be made aware of anyone new starting at the University so the correct advice can be given.
  9. AOC Minutes 22nd March 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_220324_redacted.pdf
    25 Apr 2024: and have been removed as NACWOS from the Establishment Licence. Welcome in her new role as Licence Manager. ... The training programme is expected to take around 18 months. This will hopefully help bring in new recruits.
  10. AOC Minutes 25th June 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_25.06.21_redacted.pdf
    14 May 2024: noted the new pricing will be updated on X5 in the next couple of weeks. ... 7. Training Centre Manager Report. noted had circulated a questionnaire to the NACWOs regarding new courses.
  11. AWERB 3Rs Minutes 1st November 2023 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_011123_redacted.pdf
    14 May 2024: 4. Retrospective AssessmentNone. 5. Project Licence Applications – New / Amendments. -
  12. AOC Minutes 26th November 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_26.11.21_redacted.pdf
    14 May 2024: This is not a new document, it has just been updated to include. ... It is hoped this will be started in the new year.
  13. 3Rs Minutes 3rd March 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_030321_redacted.pdf
    14 May 2024: with this new line is being underestimated. We appreciate that historically there have been discrepancies between published data and cage-side findings, and we would not like the licence to subsequently
  14. AOC Minutes 26th March 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_26.03.21_redacted.pdf
    14 May 2024: The IAT have a new database where you can amend your own records and find out your membership number. ... asked for new interview questions. has been confirmed as the new facility manager at the.
  15. 3Rs Minutes 6th October 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_061021_redacted.pdf
    14 May 2024: It was recognised that the work is carrying on under ’ new PPL.
  16. AOC Minutes January 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_22.01.21_redacted.pdf
    14 May 2024: reported that all new PIL applications, transfers, amendments and revocations should be sent to the licencing team. ... asked if had received any new interview questions since his request at a previous meeting.
  17. AWERB Standing Minutes 28th February 2024_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280224_redacted.pdf
    30 Apr 2024: Project Licences (a) New licence: ( were also in attendance) The committee discussed the following:. • ... c) New Licence: The committee discussed the following:. • Further explanation required in regards to symbols used in the Aims section. •
  18. 3Rs Minutes 4th November 2020 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_041120_redacted.pdf
    14 May 2024: a new application. • ... The use of hydrophobic sand and collecting urine on a surgical pad were suggestions that may be useful and trialling new options could be added to the 3Rs section of the
  19. AOC minutes 17th November 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_171123_redacted.pdf
    14 May 2024: b) What is happening with staff in your unit? is a new senior on. ... 9. Training and Competencies There will be new prices for the courses from January.
  20. AOC Minutes 21st May 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_21.05.21_redacted.pdf
    14 May 2024: 5. Director and Deputy Director Reports. welcomed to the meeting in her new role. ... The University is now adopting agile/hybrid working as the new normal working practice.
  21. AOC Minutes 17th December 2021

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_17.12.21_redacted.pdf
    14 May 2024: The policy is not new, it has been amended to add the.
  22. AOC Minutes 25th November 2022

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_251122_redacted_0.pdf
    14 May 2024: The Home Office attended LASA and discussed the change program but there was nothing new to report. ... 9. Training and Competencies There is a new member of staff starting on January 30th replacing.
  23. AOC Minutes 30th September 2022

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_30.09.22_redacted_0.pdf
    14 May 2024: New guidance has been shared regarding GA animals. It has been advised that wording can be added to the PEL which will cover all project licences with a standard breeding protocol ... are also using a new agency. Two porters have successfully been
  24. AOC Minutes 24th April 2020

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_24.04.20_redacted.pdf
    14 May 2024: No new experimental work has started and due to the rederivation project, breeding is being assessed on a case to case basis. ... reported that further investigations have taken place and they have taken delivery of new valves which have a better flow.
  25. 3Rs Minutes 5th May 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_050521_redacted.pdf
    14 May 2024: noted the licence holder has now changed and the new licence holder should be made aware of the advice.
  26. NPC Minutes 17th May 2019

    https://www.ubs.admin.cam.ac.uk/system/files/public/npc_minutes_170519_redacted.pdf
    14 May 2024: The new ASPeL system is due to go live on 31st August however, some technical issues are still ongoing with the Project Licenses. ... Page 3 of 4. 7. Training Centre Manager’s Report. confirmed that the core DOPs assessments for new starters should be
  27. AOC Minutes 25th February 2022

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_25.02.22_redacted.pdf
    14 May 2024: The Home Office has asked for a report after every new and amended PPL has gone through an AWERB meeting. ... The Guildhall has pulled out due to building work and the new location is yet to be confirmed.
  28. AWERB Standing Minutes 27th March 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_270324_redacted.pdf
    30 Apr 2024: Project Licences (a) New licence: was also in attendance) The committee discussed the following:. • ... Page 2 of 4. (b) New Licence: was also in attendance) The committee discussed the following:. •
  29. 3Rs Minutes 7th April 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_070421_redacted.pdf
    14 May 2024: The 3Rs Committee wish all the best for her new job in The Netherlands. •
  30. 3Rs Minutes 3rd February 2021 Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_030221_redacted.pdf
    14 May 2024: The committee were pleased to see refinements previously developed with collaborators being brought forward into this new licence. •
  31. AWERB Standing Committee Meeting Minutes 18th December 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_181223_redacted.pdf
    28 Feb 2024: Project Licences (a) New licence: The committee discussed the following:. • Further consideration should be given to the lay person in regards to the Non-Technical Summary and this should also be
  32. Developing new mulivalent recombinant vaccines platforms against…

    https://www.ubs.admin.cam.ac.uk/system/files/public/developing_new_multivalent_recombinant_vaccines_platforms_against_infectious_diseases._non-technic_redacted.pdf
    29 Apr 2024: What's the aim of this project? The overall aim of the research is to develop new and improved vaccines. ... New vaccines need to be safe, well tolerated, effective and offer broad coverage against many pathogens.
  33. Axon degeneration and repair (non-technical summary)

    https://www.ubs.admin.cam.ac.uk/system/files/public/axon_degeneration_and_repair_non-technical_summary_redacted.pdf
    30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... As we have shown, when a new 3Rs method becomes available (e.g., hiPSC-derived neurons), we
  34. Placental epignetic programming

    https://www.ubs.admin.cam.ac.uk/system/files/public/placental_epigenetic_programming_non-technical_summary_redacted.pdf
    30 Apr 2024: Our findings will help both clinical and basic science research in reproductive biology and epigenetics to generate new research questions. ... Culture methods for human placental trophoblast cells are very new and still under development.
  35. Cartilage repair and replacement

    https://www.ubs.admin.cam.ac.uk/system/files/public/cartilage_repair_and_replacement_non-technical_summary_redacted.pdf
    29 Apr 2024: Animals will be brought in and allowed to acclimatise for a few weeks - this helps them to relax in their new surroundings, gets them used to the staff and human contact ... bones, which acts as a shock absorber), to which the new implant/therapy will be
  36. Early human development and the germline (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/early_human_development_and_the_germline_non-technical_summary_redacted.pdf
    30 Apr 2024: Human embryos are highly inaccessible for research. We use animals to test new experimental approaches, and the knowledge gained can be used to investigate similar events in precious human fetuses and ... We have reduced significantly the number of mice
  37. New treatments for renal and liver disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatments_for_renal_and_liver_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: In work under this licence we aim to identify new treatments for CKD, AKI and NAFLD. ... project? We hope to optimise new imaging efficacy endpoints that will allow assessment of animals over time.
  38. In vivo compressive forces (non-technical summary)_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/in_vivo_compressive_forces_non-technical_summary_redacted.pdf
    30 Apr 2024: For each stock a new generation will be grown every 18 months (3.3 generations per line in 5 years). ... For each we will breed a new generation every 18 months (2560x3.3=8448).
  39. Models of mitochondrial diseases, pathogenesis and therapy

    https://www.ubs.admin.cam.ac.uk/system/files/public/models_of_mitochondrial_diseases_pathogenesis_and_therapy_non-technical_summary_redacted.pdf
    30 Apr 2024: 1. New mouse models of mitochondrial disease which carry mutations similar to those found in humans. ... The remaining 20% will be neonates (new born pups up to weaning - approx.
  40. Mechanisms controlling cell division and cell identity during…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_cell_division_and_cell_identity_during_development_reprogramming_and_disease_redacted.pdf
    30 Apr 2024: For example, understanding how cell identity can contribute to diseases may help in the discovery of new treatments. ... I am currently on the European Xenopus Resource Steering Committee where new developments in frog husbandry are often discussed.
  41. Understanding Infection Pathogenesis to Guide Therapies…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf
    30 Apr 2024: 6.1 million deaths annually (https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death). ... This is confounded by the fact that there have been very few new antimicrobial products that have been developed over the last 15 years.
  42. Mechanisms of organ development and disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_of_organ_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: We will make a new generation for each line every year (5 generations per line). ... In addition, when generating new genetically modified lines, the F0 embryos need to be genotypically screened.
  43. Interaction between the immune system and tumours (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf
    30 Apr 2024: To the wider pharmaceutical industry and patients this could lead into the development of new anti-cancer therapies. ... Pilot studies are used to establish the correct dose of reagents/cells, timelines, and to generate baseline data for new experiments.
  44. Development of humanised mouse models for study of cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf
    29 Apr 2024: This could lead to development of new therapies that are more effective and cause fewer side effects to patients. ... More specifically, we expect to generate at least one new therapy and advance it to a stage that it can be investigated further in large
  45. Discovery and development of treatments for immunological diseases

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf
    29 Apr 2024: goal by enabling us to test new therapeutic hypothesis in vivo relevant to new treatments for immune mediate diseases. ... This de-risks again the potential for using new therapeutic agents which are unlikely to achieve active concentrations at the
  46. PK and PKPD studies to support Respiratory and Immunology research

    https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf
    30 Apr 2024: To enable us to decide what doses of new treatments we need to use in our respiratory and immunology disease models. ... There are multiple stages of non-animal screening of new molecules that are in place before testing in rodent.
  47. Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf
    30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... We also expect, in the medium term, that our research will lead to the development of new behavioural treatments.
  48. Proteotoxicity in development and ageing (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf
    30 Apr 2024: There is no cure for neurodegenerative disorders and thus, finding a new common target is at utmost importance. ... We have created new mouse lines with specific mutations in genes that disrupt one of the stress response pathway that is called
  49. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: Discoveries made on new bacterial species will be published and available to other researchers. ... We continuously consider their use and development in light of new experimental data.
  50. Development of Molecular Imaging and Theranostic Agents for Cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf
    30 Apr 2024: Some of these methods are aimed at providing information to develop new therapies for these diseases. ... We are developing new ways to image cancer and inflammation and find novel ways of treating these diseases.
  51. Gut hormone modulation of metabolism (non-technical summary)_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/gut_hormone_modulation_of_metabolism_non-technical_summary_redacted.pdf
    30 Apr 2024: Our findings should guide these attempts and clarify the mechanisms of action these new therapies employ. ... When animals are exposed to new diets or environments they receive training sessions.

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