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101 - 110 of 146 search results for news |u:www.ubs.admin.cam.ac.uk

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  2. Nutrient sensing in the brain

    https://www.ubs.admin.cam.ac.uk/system/files/public/nutrient_sensing_in_the_brain_non-technical_summary_redacted.pdf
    30 Apr 2024: In the short term, the scientific community will gain new information on the pathways and genes that we will investigate. ... Numbers are being adjusted in Dec 2022 following the obtention of new research funding.

  3. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: For breeding design we use several online resources, especially when bringing in a new strain. ... care for our strains and to identify any new and better treatments that could be utilised.

  4. Embryonic origins of heart disease

    https://www.ubs.admin.cam.ac.uk/system/files/public/embryonic_origins_of_heart_disease_non-technical_summary_redacted.pdf
    29 Apr 2024: The new bedding material generated much less dust. What published best practice guidance will you follow to ensure experiments are conducted inthe most refined way? ... Therefore, the project licence holder will have regular discussions with the Named

  5. Epigenetic inheritence and the control of developmental and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf
    30 Apr 2024: This means that others do not need to generate new mutants or samples, minimising animal numbers. ... For any new procedures we will review published protocols from experienced collaborators before conducting any experiments.

  6. Understanding the cell biology behind cardiovascular diseases…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_cell_biology_behind_cardiovascular_diseases_non-technical_summary_redacted.pdf
    30 Apr 2024: In new systems pilot studies are utilised to ensure the system works as intended with a small group (e.g. ... Mice would also be habitualised to a new restraint before, e.g., BP measurement.

  7. Regulation of the mammalian reproductive axis

    https://www.ubs.admin.cam.ac.uk/system/files/public/regulation_of_the_mammalian_reproductive_axis._non-technical_summary_redacted.pdf
    30 Apr 2024: until we require new offspring. ... I will also have regular discussions with the Named Persons and animal technicians to review current approaches and whether there are any new 3R opportunities.

  8. Tissue response following synovial joint injury and potential for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/tissue_response_following_synovial_joint_injury_and_potential_for_therapies_to_restore_joint_structu_redacted.pdf
    30 Apr 2024: These new discoveries will be shared with others at local, national and international scientific meetings and in widely available publications. ... In more detail, it is our expectation that our research will produce one new.

  9. Exploring Bioelectronic Approaches to Nervous System Restoration in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/exploring_bioelectronic_approaches_to_nervous_system_restoration_in_large_animals_non-technical_sum_redacted.pdf
    30 Apr 2024: Also, these devices will help us learn more about these diseases and might help find even more new treatments. ... Subscribing to the NC3Rs newsletter (https://www.nc3rs.org.uk/news) to receive regular updates on new ideas and research related to the 3Rs.

  10. Molecular mechanisms of tolerance and immunosuppression…

    https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_mechanisms_of_tolerance_and_immunosuppression_non-technical_summary_redacted.pdf
    30 Apr 2024: Both are important immunological processes and targets for the development of new drugs. ... There is a great unmet clinical need in this area and our experiments could inform the development of new therapeutics.

  11. Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf
    30 Apr 2024: The treatments that are validated in the project may include new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

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