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151 - 160 of 190 search results for news |u:www.ubs.admin.cam.ac.uk

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  2. Development of novel therapeutics for pain (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_novel_therapeutics_for_pain_non-technical_summary_redacted.pdf
    30 Apr 2024: relevant disease animal models to give us an extra layer of confidence in developing these new medications. ... In all new studies undertaken, the level of insult will be assessed before conducting further studies.

  3. Multi-tissue mechanics in the development and engineering of the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/multi-tissue_mechanics_in_the_development_and_engineering_of_the_posterior_body_axis_non-technical_redacted.pdf
    30 Apr 2024: We will make a new generation for each line every year (5 generations per line). ... In addition, when generating new genetically modified lines, the F0 embryos need to be genotypically screened.

  4. Potent monoclonal antibodies for biologics discovery (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/potent_monoclonal_antibodies_for_biologics_discovery_non-technical_summary_redacted.pdf
    30 Apr 2024: Any new drug development can take up to 10-12 years before it can be used on human patients. ... We have developed a new method where we can screen antibody secreting B-cells directly for antigen binding.

  5. 3Rs - search page | University Biomedical Services (UBS)

    https://www.ubs.admin.cam.ac.uk/3rs/search/category/other-resources
    28 Jul 2024: Search site. Other Resources. University Biomedical Services (UBS). 3Rs - search page. Search found 12 items. (-) Remove Other Resources filter Other Resources. Animal Research Info. Topic: Other Resources. Norecopa- Consensus Meetings on The Care

  6. Development of nerve neuroprosthetic treatment

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_nerve_neuroprosthetic_treatments_non-technical_summary_redacted.pdf
    29 Apr 2024: Supervisors teaching new PILs will do so following LASA guiding principles to ensure new users are properly trained to perform any procedures necessary. ... Supervisors teaching new licence holders will do so following LASA guiding principles to ensure

  7. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: In the long-term we hope that this work will lead to translational outputs in the form of clinical trials around new therapeutic agents. ... establishing a new colony of mice from frozen eggs and/or sperm) any further strains of mice we need for this

  8. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf
    30 Apr 2024: They enable us to test the effect of new treatments in a relevant and intact biological system. ... This project will provide important information to progress new treatments through the phases of drug development.

  9. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: There is an urgent need for new drugs and therapies to slow, delay and prevent proteinopathy diseases. ... Overall, we hope to identify new genes and compounds that allow us to better understand and manipulate neurodegeneration.

  10. Metabolic basis of microglia function in development (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/metabolic_basis_of_microglia_function_in_development_non-technical_summary_redacted.pdf
    30 Apr 2024: Finally, full training will be provided to new technicians who are unfamiliar with these procedures. ... This will ensure that we maintain compliance should any new updates be posted.

  11. Pharmacological evaluation of imaging agents and development of…

    https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf
    30 Apr 2024: As new molecular targets involved in diseases are discovered, the imaging agents that are required for imaging them need to be developed and evaluated in a manner similar to the drug ... When new drugs for removing these proteins are being developed it

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