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30 Mar 2021: Graeme continued to keep in touch with colleagues and friends at LMB, including celebrating the opening of the new LMB building at the LMB Alumni Symposium in 2014. ... Richard Durbin and the LMB News Team. Primary Sidebar. Search. Search this website.

2 Jul 2021: Published on. 2 July, 2021. Maria Leptin is the new President of the European Research Council starting from 1 October 2021.

30 Mar 2021: Uli Arndt (1924 - 2006) His many friends and colleagues around the world will be very sad to learn that Uli died on 24th March, aged 81, from cancer which

24 Aug 2021: For his ground-breaking methodological developments in image processing and analysis in cryo-EM, Sjors Scheres has been awarded the Royal Society’s Leeuwenhoek Medal.

30 Mar 2021: Richard Perham (1937 - 2015) Richard Perham died on Saturday 14 February 2015, after a short illness, at the age of 77. Richard began as a PhD student in

13 Dec 2021: Two LMB alumni, Christian Münch and Clemens Plaschka, are among twenty-six life scientists to be welcomed into EMBO’s Young Investigator Network. They

12 May 2021: M. Madan Babu, former group leader in the LMB’s Structural Studies Division, has been elected into the Fellowship of the Academy of Medical Sciences.

29 Jan 2021: This process might play a role in virus spread between cells even in the absence of production of new virus particles. ... The emergence of new SARS-CoV-2 variants is a real concern as they can threaten the effectiveness of the approved SARS-CoV-2

23 Jun 2021: Postdoc Maria Marti Solano, from our Structural Studies Division, discusses her research into whether genetic or patient-specific factors impact receptor

30 Mar 2021: With Maier-Leibnitz, they recruited the young German and French scientists and engineers who designed and built a new generation of instruments (some of which were politely considered to be ‘odd’ ... He established a group in structural virology that

31 Mar 2021: Original hand-drawn design from the 1980s. Before a new piece of equipment or machinery can be made, we first need to nail down the design. ... More recently, I’ve worked with Richard Henderson and Greg McMullan on various high vacuum test rigs for the

21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.

11 Oct 2021: John Wade from The University of Melbourne and John Jones from Balliol College, University of Oxford have partnered to essay the life and work of Robert

5 May 2021: Fourteen primary schools participated in the 2020 Science Image Award competition, with the winning image taken by a child at Barnham Primary School near Thetford.

31 Mar 2021: Gerry Rubin: Looking Back Gerry Rubin was a PhD student in the Cell Biology Division from 1971-1974. For the December 2019 LMB Alumni Newsletter, he

14 Apr 2021: Henderson, R. IUCrJ 3, 3-7 (2016). CryoEM at IUCrJ: a new era. ... Caspar, D.L.D. Nature, News & Views 345, 666-667 (1990). Bacteriorhodopsin - at last!

24 Nov 2021: DNA damage caused by formaldehyde is repaired involving CSA and CSB genes. KJ Patel’s lab have shown how, when this pathway is mutated such as in people with Cockayne syndrome, the appetite suppression hormone GDF15 is released leading to severe

30 Apr 2021: the new virulent clones of M. ... abscessus, and prevent the emergence of new ones. Without this, it is likely that increased opportunities for direct transmission of pathogenic mycobacteria – because of factors such as rising population density or

21 May 2021: David Blow (1931 - 2004) Sadly, David Blow died on 8th June 2004, aged 72, having survived nearly a year with cancer. David first joined Max Perutz as a

24 Aug 2021: 100 }. 101 }. 102 if (! found) {. 103 one_way_probe_contact_t new_contact(from_atom);. ... 104 new_contact.add(to_atom);.

25 May 2021: Self–assembling model of the protein shell of a spherical virus particle The model illustrates the two main principles of the structure:Each unit

12 Jul 2021: Here, David discusses building maintenance, the team’s 24/7 ‘on call’ support service, and installing a new Scientific Computing Server Room.

4 Jun 2021: The group created polymers made of up to eight monomers strung together, and encoded the synthesis of twenty-two distinct new polymer sequences. ... Science News Story: New approach to rewriting bacteria’s genetic code could lead to novel medicines.

30 Mar 2021: John Kendrew (1917 - 1997) In 1945, John Kendrew joined Max Perutz at the Cavendish Laboratory in Cambridge. Together they would share three great

15 Oct 2021: These findings represent a new and important insight into how different cell types maintain homeostasis whilst accommodating changes in cytosolic macromolecular crowding. ... to sustain increased cardiac function in the morning. From a clinical

6 Dec 2021: Around 800 pupils from nine schools competed in the Microscopes4Schools Science Image Award producing striking images of the living world.

9 Mar 2021: Leo’s group has now exploited new understanding of Trim-Away’s mechanism of activation to expand the technology’s toolbox.

21 May 2021: Celia Milstein (1928 – 2020) Celia Milstein was born in 1928 and came to Britain from Argentina in the late 1950s with César, her husband, and they worked

24 Aug 2021: Returns. the molecule number of the new map. Return -1 if unable to make a variance map. ... the function passed to lbg, so that it calls it when a new SBase comp_id is required.

30 Jun 2021: Membrane remodelling and repair are essential for all cells. Buzz Baum’s group have shown that bacterial proteins Vipp1 and PspA are members of a family of membrane-remodelling proteins once thought to be exclusive to eukaryotes.

21 Apr 2021: To offset this shortening, an essential enzyme called telomerase rebuilds the telomeres by synthesizing new telomeric DNA repeats at chromosome ends. ... Currently, there are no telomerase-based therapies available, however this new atomic model provides

5 Oct 2021: Excitingly, I believe we are on the cusp of a new era in science with AI poised to be a powerful tool for accelerating scientific discovery itself. ... At DeepMind, John is leading the development of new methods to apply machine learning to protein

24 Mar 2021: The advent of brain organoid technology has enabled scientists to begin to ask what makes us human. Madeline Lancaster’s group has identified differences in early brain development that can help to explain the increased number of neurons in human

26 Oct 2021: Now, this exciting new work sheds light on how the regulation of replisome disassembly is achieved through a simple and conserved mechanism whereby the SCF.

21 May 2021: Carl-Ivar Brändén (1934 - 2004) Carl-Ivar Brändén died on 28th April 2004, aged nearly 70 after a lifetime in protein crystallography. His Ph.D. and early

24 Aug 2021: 43. 48 int new_generic_object_number_for_molecule(const std::string &obj_name, int imol);. ... int new_generic_object_number(const std::string &obj_name). create a new generic object with name objname.

25 Mar 2021: The coming of age of de novo protein design. https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.

27 Sep 2021: I was also keen to experience a totally new field and working environment. ... You should absolutely go for it! I cannot express how much I have gained from this experience both in terms of new skills, new insights into the world of science policy

8 Jul 2021: In her new research laboratory at Flinders she will continue her research using Nematode worms to better understand chronic pain.

24 Aug 2021: 28 // Create a new molecule, which is a copy of this molecule without the. ... 141 // name, a reference-comp-id and a compd-id for the new residue (type).

2 Jul 2021: Although the cytoskeleton is known to play an important role in determining cell, and therefore organ, shape, how components of the cytoskeleton are reorganised during tube formation is unclear. Katja Röper’s group has identified a mechanism

19 Jul 2021: Residential course in Biology and Genetics To help inspire the next generation of scientists, the LMB participated in an annual five-day intensive

9 Jun 2021: She commented: ‘The 3Rs prize combined with the excellent LMB scientific atmosphere, will allow me to explore new directions and to specifically investigate the role of the choroid plexus in protein ... Credit NC3Rs. In Laura’s innovative study, she

31 Mar 2021: Hayley Sharpe: Looking back Hayley Sharpe was a PhD student in the Cell Biology Division from 2006-2010. She is now a tenure track Group Leader at the

22 Oct 2021: possible.”. Silvia recently completed a PhD in Madeline Lancaster’s group and is now a postdoc at the Sloan Kettering Institute, New York. ... This work provided new paradigms for how a dimeric GPCR gets activated, and I am now investigating how this

10 Mar 2021: Rare lipids in our cell membranes act as postcodes to operate regulatory processes such as autophagy and endocytosis. Roger Williams, together with Sean Munro’s and John Brigg’s groups, have shown how the G-proteins Rab1 and Rab5 activate these

6 Aug 2021: A better understanding of the mechanisms of fundamental viral functions might be the key to finding new and more effective treatments for this disease.

4 Nov 2021: Cryo-EM analysis reveals structure of structural maintenance of chromosomes (SMC) complex, and shows for the first time how the protein machinery entraps two DNA helices simultaneously in order to individualise chromosomes.

11 Feb 2021: If I had missed the 8 pm news about Dolly, I might have followed the path to medical school.

19 Apr 2021: Repetitive peptides from the C9orf72 gene contribute to the most prevalent form of motor neurone disease, but it has been unclear how. Simon Bullock’s group help show how these peptides bind to both motor proteins and microtubule tracks to block