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  2. Per Bullough - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-per-bullough/
    Thumbnail for Per Bullough - MRC Laboratory of Molecular Biology 30 Mar 2021: Search this website. Per Bullough. Per Bullough was a Ph.D. student in the Structural Studies Division at LMB from 1985-1989 developing new methods of low-dose imaging of biological
  3. Mike Clark - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mike-clark/
    Thumbnail for Mike Clark - MRC Laboratory of Molecular Biology 30 Mar 2021: Mike Clark Mike Clark was a Ph.D. student working with Cesar Milstein from 1978-1981 carrying out research into the recently described technology of
  4. ‘Making Visible’ poetic illuminations move to the LMB - MRC…

    https://www2.mrc-lmb.cam.ac.uk/making-visible-poetic-illuminations-move-to-the-lmb/
    Thumbnail for ‘Making Visible’ poetic illuminations move to the LMB - MRC Laboratory of Molecular Biology 10 Dec 2021: Making Visible’ allowed colleagues to connect with each other and explore their scientific work in new, creative ways.
  5. Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/geoffrey-grigg/
    Thumbnail for Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology 21 May 2021: Geoffrey Grigg (1926 - 2008) Geoffrey Grigg was an Australian visitor to the LMB with Fred Sanger in 1972-1974 and Greg Winter in 1988, and often visited
  6. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  7. Tail of SARS-CoV-2 Spike protein is optimised to reach the cell…

    https://www2.mrc-lmb.cam.ac.uk/tail-of-sars-cov-2-spike-protein-is-optimised-to-reach-the-cell-surface-causing-infection-to-spread-to-neighbouring-cells/
    Thumbnail for Tail of SARS-CoV-2 Spike protein is optimised to reach the cell surface causing infection to spread to neighbouring cells - MRC Laboratory of Molecular Biology 10 Sep 2021: Most of these new Spike proteins accumulate in an intracellular structure named Golgi which assembles new viruses. ... the Golgi apparatus, then hold it there whilst new viruses are made.
  8. Early transcriptional patterning of a forming tissue is essential to…

    https://www2.mrc-lmb.cam.ac.uk/early-transcriptional-patterning-of-a-forming-tissue-is-essential-to-morphogenesis-of-a-tubular-organ/
    Thumbnail for Early transcriptional patterning of a forming tissue is essential to morphogenesis of a tubular organ - MRC Laboratory of Molecular Biology 8 Nov 2021: Time-lapse quantitative study of developing salivary glands in Drosophila embryos, conducted by Katja Röper’s group, reveals the key control factors behind cells’ behavioural transitions that are essential for correct organ formation.
  9. Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf
    26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C,
  10. Coot Scripting Interface: cc-interface.hh Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/cc-interface_8hh_source.html
    24 Aug 2021: 474 // return the status and vector of chain-ids of the new chain ids. ... 1312 mmdb::Manager new_molecule_by_symmetry_matrix_from_molecule(mmdb::Manager mol,.
  11. The Coot User Manual

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html
    1 Mar 2021: The Coot User Manual
  12. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  13. How the fate of immune cell precursors is decided - MRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/how-the-fate-of-immune-cell-precursors-is-decided/
    Thumbnail for How the fate of immune cell precursors is decided - MRC Laboratory of Molecular Biology 11 Jan 2021: 11 January, 2021. Discovery of a new checkpoint that controls the development of innate immune cells with a key role in parasite defence and allergy. ... This led to their proposal of a new transcription factor network to explain how RORα regulates
  14. Behind the scenes: Paul Hart and the development of IT at the LMB -…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-paul-hart-and-the-development-of-it-at-the-lmb/
    Thumbnail for Behind the scenes: Paul Hart and the development of IT at the LMB - MRC Laboratory of Molecular Biology 20 Dec 2021: The biggest challenge. Several year later the new building project came my way. ... I’d worked on a couple of new building projects, but never as a lead.
  15. Dan Brown (1923 - 2010) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dan-brown-1923-2010/
    Thumbnail for Dan Brown (1923 - 2010) - MRC Laboratory of Molecular Biology 30 Mar 2021: Dan Brown 1923 - 2012 It is with great sadness that we report that Dan Brown, who had been battling cancer for some time, died on Tuesday April 24, 2012,
  16. Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/
    Thumbnail for Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology 30 Mar 2021: the centre of the new field of molecular biology.
  17. Dinolite Instructions

    https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions_detailed_2021.22_LJM.doc
    18 Oct 2021: If no new image appears, move the mouse until it does (you may see the last image taken otherwise). ... 5. To take a new image, place your mouse over anything other than an existing thumbnail.
  18. Coot Scripting Interface: c-interface.h Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html
    24 Aug 2021: 447. 457 int add_ligand_delete_residue_copy_molecule(int imol_ligand_new,. ... If it doesn't then we /. 1527 / go down a (new 20060920) different path. /.
  19. Setting the stage: development of sample holders for electron ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21295
    21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.
  20. KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21355
    27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  21. KENDREW LECTURE(Part 2) Wednesday 13th October @ 4.00 pmDetails ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21356
    27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  22. Behind the scenes: Maria Daly and the flow cytometry facility - MRC…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-maria-daly-and-the-flow-cytometry-facility/
    Thumbnail for Behind the scenes: Maria Daly and the flow cytometry facility - MRC Laboratory of Molecular Biology 31 Mar 2021: Behind the scenes: Maria Daly and the flow cytometry facility Maria Daly is manager of the LMB’s Flow Cytometry Facility, which provides LMB scientists
  23. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure.
  24. BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf
    29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in
  25. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  26. Mark Bretscher - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mark-bretscher/
    Thumbnail for Mark Bretscher - MRC Laboratory of Molecular Biology 30 Mar 2021: Mark S. Bretscher Mark Bretscher studied Chemistry at the University of Cambridge, before joining the MRC Laboratory of Molecular biology as a research
  27. Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/max-perutz-1914-2002/
    Thumbnail for Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology 30 Mar 2021: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
  28. Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC…

    https://www2.mrc-lmb.cam.ac.uk/francis-crick-lecture-to-be-given-by-michel-c-nussenzweig/
    Thumbnail for Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC Laboratory of Molecular Biology 8 Nov 2021: Michel received a B.C. summa cum laude from New York University in 1976, a PhD degree with Ralph Steinman from Rockefeller University in 1981 and an M.D. ... degree from New York University Medical School in 1982. Following this he completed a medical
  29. Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC…

    https://www2.mrc-lmb.cam.ac.uk/michel-goedert-awarded-the-2021-hartwig-piepenbrock-dzne-prize/
    Thumbnail for Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC Laboratory of Molecular Biology 15 Oct 2021: Hopefully, the new knowledge will lead to the development of safe and effective mechanism-based therapies for common neurodegenerative diseases.”.
  30. Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/wasi-faruqi-awarded-mbe-in-queens-birthday-honours/
    Thumbnail for Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory of Molecular Biology 14 Jun 2021: Wasi (Abdul Raffey) Faruqi, from the LMB’s Structural Studies Division, has been made a MBE in the Queen’s 2021 Birthday Honours List
  31. Heart cell clocks help coordinate daily cardiac function - MRC…

    https://www2.mrc-lmb.cam.ac.uk/heart-cell-clocks-help-coordinate-daily-cardiac-function/
    Thumbnail for Heart cell clocks help coordinate daily cardiac function - MRC Laboratory of Molecular Biology 21 Oct 2021: Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through
  32. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html
    14 Apr 2021: Henderson, R. IUCrJ 3, 3-7 (2016). CryoEM at IUCrJ: a new era. ... Caspar, D.L.D. Nature, News & Views 345, 666-667 (1990). Bacteriorhodopsin - at last!
  33. John Finch Collection - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/john-finch-collection/
    Thumbnail for John Finch Collection - MRC Laboratory of Molecular Biology 31 Mar 2021: He came to the new LMB in 1962 with the Birkbeck group, which was now led by Aaron Klug after Rosalind’s death in 1958.
  34. César Milstein Lecture to be given by Hans Clevers - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-hans-clevers/
    Thumbnail for César Milstein Lecture to be given by Hans Clevers - MRC Laboratory of Molecular Biology 23 Nov 2021: Hans Clevers from the Hubrecht Institute will deliver the 2021 César Milstein Lecture on how organoids can be used to model human diseases.
  35. Bretscher Archive - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/manuscripts-correspondence/bretscher-archive/
    Thumbnail for Bretscher Archive - MRC Laboratory of Molecular Biology 28 Sep 2021: Search this website. Bretscher Archive. The MRC Unit moved out of the Cavendish Laboratory to the new LMB site in early 1962.
  36. A colourful welcome back for the LMB Arts and Crafts Show - MRC…

    https://www2.mrc-lmb.cam.ac.uk/a-colourful-welcome-back-for-the-lmb-arts-and-crafts-show/
    Thumbnail for A colourful welcome back for the LMB Arts and Crafts Show - MRC Laboratory of Molecular Biology 5 Aug 2021: The LMB Arts and Crafts Show: showcasing the creative talents of the LMB
  37. Madeline Lancaster on serendipity and adventure in science - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-on-serendipity-and-adventure-in-science/
    Thumbnail for Madeline Lancaster on serendipity and adventure in science - MRC Laboratory of Molecular Biology 22 Sep 2021: Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids –
  38. Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf
    29 Aug 2021: Q5 High-Fidelity 2X Master Mix (New England Biolabs,. Ipswich, MA, USA) as per manufacturer’s instructions.
  39. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  40. Dr. George Pieczenik - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dr-george-pieczenik/
    Thumbnail for Dr. George Pieczenik - MRC Laboratory of Molecular Biology 30 Mar 2021: Dr. George Pieczenik Dr. George Pieczenik worked in the MRC Laboratory of Molecular Biology at intervals during the years 1972-1987. He was an early
  41. Bernard Jacrot - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/bernard-jacrot/
    Thumbnail for Bernard Jacrot - MRC Laboratory of Molecular Biology 30 Mar 2021: With Maier-Leibnitz, they recruited the young German and French scientists and engineers who designed and built a new generation of instruments (some of which were politely considered to be ‘odd’ ... He established a group in structural virology that
  42. Madeline Lancaster awarded the 2021 ISSCR Dr Susan Lim Award - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-awarded-the-2021-isscr-dr-susan-lim-award/
    Thumbnail for Madeline Lancaster awarded the 2021 ISSCR Dr Susan Lim Award - MRC Laboratory of Molecular Biology 26 Jan 2021: They found that ChP cells express ACE2, the receptor needed for SARS-CoV-2 entry, on their surface and that the virus was able to infect and produce new virus inside ... The development of cerebral organoids has significant implications not only for
  43. Furin protease is not essential for SARS-CoV-2 infection - MRC…

    https://www2.mrc-lmb.cam.ac.uk/furin-protease-is-not-essential-for-sars-cov-2-infection/
    Thumbnail for Furin protease is not essential for SARS-CoV-2 infection - MRC Laboratory of Molecular Biology 29 Jan 2021: This process might play a role in virus spread between cells even in the absence of production of new virus particles. ... The emergence of new SARS-CoV-2 variants is a real concern as they can threaten the effectiveness of the approved SARS-CoV-2
  44. Chris Tate and Sjors Scheres elected Fellows of Royal Society - MRC…

    https://www2.mrc-lmb.cam.ac.uk/chris-tate-and-sjors-scheres-elected-fellows-of-royal-society/
    Thumbnail for Chris Tate and Sjors Scheres elected Fellows of Royal Society - MRC Laboratory of Molecular Biology 6 May 2021: Each year the Fellows of the Royal Society elect up to 52 new Fellows, and up to 10 new Foreign Members. ... Our new Fellows and Foreign Members are all at the forefronts of their fields from molecular genetics and cancer research to tropical open
  45. Behind the Scenes with... Steve Scotcher - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/steve-scotcher/
    Thumbnail for Behind the Scenes with... Steve Scotcher - MRC Laboratory of Molecular Biology 31 Mar 2021: Original hand-drawn design from the 1980s. Before a new piece of equipment or machinery can be made, we first need to nail down the design. ... More recently, I’ve worked with Richard Henderson and Greg McMullan on various high vacuum test rigs for the
  46. 16262551036386 1..32

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf
    14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received:
  47. A unified evolutionary origin for the ubiquitous protein transporters …

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/BMC_Biology_2021.pdf
    15 Dec 2021: s hydrophilic groove and its capping hydrophobicresidue are homologous to key residues in SecY’s hydro-philic funnels and its pore ring, respectively.In light of this new correspondence, we
  48. The mechanisms of integral membrane protein biogenesis

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf
    22 Sep 2021: These areas have recently seen the discovery of new machinery, mechanis-tic insights from structural and bioinformatics analysis, and the emergence of new concepts. ... Here we consider comparatively recent new insights into the basis of SRP substrate
  49. Science Journals — AAAS

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf
    26 Aug 2021: The PSMC5 construct for in vitro translation in the PURE system was similar to that in pSP64, but in the T7-based PURExpress plasmid from New England Biolabs. ... The resin was then. 6. washed 5 times in PSB, and transferred to a new tube.
  50. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  51. Hans Boye - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-hans-boye/
    Thumbnail for Hans Boye - MRC Laboratory of Molecular Biology 30 Mar 2021: Hans Boye Hans Boye was a research student with Francis Crick from October 1961-1964, and was Crick's second and last student. His area of research was on

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