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  2. Structures of virus-like capsids involved in learning and memory…

    https://www2.mrc-lmb.cam.ac.uk/structures-of-virus-like-capsids-involved-in-learning-and-memory-formation/
    Thumbnail for Structures of virus-like capsids involved in learning and memory formation - MRC Laboratory of Molecular Biology 23 Jan 2020: The neuronal gene Arc plays important roles in neural plasticity, learning and memory-related molecular processes and has been shown to mediate intercellular RNA transfer by forming viral-like capsids. John Briggs’ group has now solved the first
  3. Unravelling the replisome: how a molecular machine overcomes…

    https://www2.mrc-lmb.cam.ac.uk/unravelling-the-replisome-how-a-molecular-machine-overcomes-obstacles-to-dna-replication/
    Thumbnail for Unravelling the replisome: how a molecular machine overcomes obstacles to DNA replication - MRC Laboratory of Molecular Biology 4 May 2020: to reproduce new double-stranded DNA. ... These processes are tightly coupled by the replisome complex to avoid stretches of exposed single-stranded DNA between the point of unwinding and the point of synthesis of new DNA.
  4. Tracing a transcription initiation factor’s molecular journey across…

    https://www2.mrc-lmb.cam.ac.uk/tracing-a-transcription-initiation-factors-molecular-journey-across-evolutionary-timescale/
    Thumbnail for Tracing a transcription initiation factor’s molecular journey across evolutionary timescale - MRC Laboratory of Molecular Biology 13 May 2020: M Madan Babu’s group publishes a comprehensive model for the functional innovations of TBP.
  5. Liz Miller: Signed, sealed, delivered - protein trafficking in the…

    https://www2.mrc-lmb.cam.ac.uk/liz-miller-signed-sealed-delivered-protein-trafficking-in-the-endoplasmic-reticulum/
    Thumbnail for Liz Miller: Signed, sealed, delivered - protein trafficking in the endoplasmic reticulum - MRC Laboratory of Molecular Biology 13 Oct 2020: After hearing him talk in a new group leaders’ seminar series, Liz realised that her colleague Madan Babu, who works on intrinsically disordered proteins, could help her a lot in understanding ... The job I’ve given myself is to do preliminary
  6. A splice of life - Chemistry World looks at how structural biology…

    https://www2.mrc-lmb.cam.ac.uk/a-splice-of-life-chemistry-world-looks-at-how-structural-biology-has-revealed-the-secrets-of-the-spliceosome/
    Thumbnail for A splice of life - Chemistry World looks at how structural biology has revealed the secrets of the spliceosome - MRC Laboratory of Molecular Biology 24 Mar 2020: Clare Sansom describes the history of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group. More...
  7. Emmanuel Levy has been announced as the Blavatnik Awards for Young…

    https://www2.mrc-lmb.cam.ac.uk/emmanuel-levy-has-been-announced-as-the-blavatnik-awards-for-young-scientists-in-israel-2020-laureate-in-chemistry/
    Thumbnail for Emmanuel Levy has been announced as the Blavatnik Awards for Young Scientists in Israel 2020 Laureate in Chemistry - MRC Laboratory of Molecular Biology 30 Jan 2020: The Blavatnik Awards honour outstanding, innovative scientists at the early stages of their careers. Emmanuel has been recognised for his work on protein
  8. Inspiring students to think about science in a different way through…

    https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/supporting-education/inspiring-students-to-think-about-science-in-a-different-way-through-dance/
    Thumbnail for Inspiring students to think about science in a different way through dance - MRC Laboratory of Molecular Biology 21 Feb 2020: the arts and sciences are a really powerful way to reach new audiences.”.
  9. First complete atomic model of condensin lays foundation for…

    https://www2.mrc-lmb.cam.ac.uk/first-complete-atomic-model-of-condensin-lays-foundation-for-understanding-chromosome-compaction/
    Thumbnail for First complete atomic model of condensin lays foundation for understanding chromosome compaction - MRC Laboratory of Molecular Biology 14 Jul 2020: Each of our cells contains about two metres of DNA. To be able to store all of this, the DNA must be very tightly compacted. Jan Löwe’s group have produced the first atomic model of condensin, a complex known to have a role in compacting DNA into
  10. Cell-invading bacteria are converted into signalling platforms that…

    https://www2.mrc-lmb.cam.ac.uk/cell-invading-bacteria-are-converted-into-signalling-platforms-that-may-trigger-septic-shock/
    Thumbnail for Cell-invading bacteria are converted into signalling platforms that may trigger septic shock - MRC Laboratory of Molecular Biology 15 Jun 2020: Septic shock is a common cause of death that can be triggered by LPS, a component of the outer membrane of some bacteria. Felix Randow’s group has shown how the immune response against cytosol-invading bacteria is activated by a signalling
  11. LMB participates in UK-wide COVID-19 Protein Portal to provide…

    https://www2.mrc-lmb.cam.ac.uk/lmb-participates-in-uk-wide-covid-19-protein-portal-to-provide-essential-reagents-for-sars-cov-2-research/
    Thumbnail for LMB participates in UK-wide COVID-19 Protein Portal to provide essential reagents for SARS-CoV-2 research - MRC Laboratory of Molecular Biology 12 May 2020: UK consortium of leading protein production laboratories provide protein reagents for SARS-CoV-2 research for free, in an Open Science initiative led by Wellcome and UKRI.
  12. Madeline Lancaster: The accidental organoid - mini-brains as models…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-the-accidental-organoid-mini-brains-as-models-for-human-brain-development/
    Thumbnail for Madeline Lancaster: The accidental organoid - mini-brains as models for human brain development - MRC Laboratory of Molecular Biology 11 Feb 2020: As a very new postdoc in Jürgen Knoblich’s lab in Vienna, she was trying to get mouse neural epithelial cells to form neural rosettes, but couldn’t get the cells ... LMB trusts me to think about these questions is great.” And she’s not felt
  13. Cryo-EM Model-Buildingwith Modern Coot Paul Emsley@ Ben Gurion…

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-2020-nov-slac.pdf
    10 Nov 2020: Where does Cryo-EM Coot fit into the various builds/releases? What's new in 0.9 and how does it help? –
  14. LMB Band 5 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/research/animal-research/lmb-band-5/
    Thumbnail for LMB Band 5 - MRC Laboratory of Molecular Biology 21 Feb 2020: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. LMB Band
  15. Impress

    https://www2.mrc-lmb.cam.ac.uk/coot/ephemera/beyond-coloured-lines.pdf
    28 Sep 2020: how depth is represented in 3D applications– problems with the current representation– Screenshots: how New Coot is an improvement on Old Coot. ... Ambient New Lighting Model:. – Ambient, Diffuse, Specular, Fresnel, Ambient Occlusion– Not yet:
  16. MD1-118 Hippocrates additive screen

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/LMB%20plates/Addit-03.pdf
    13 Oct 2020: The Hippocrates Additive Screen is a new 48-condition additive screen, containing a library of unique drug-like compounds to enhance protein stability and crystallisability.
  17. EMBO Practical Course on the Crystallization of Macromolecular…

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/cv/2020_01_Carter_CV.pdf
    31 Jan 2020: HONOURS AND AWARDS: Apr 2018 Wellcome Investigator Award May 2016 EMBO Membership Dec 2012 Wellcome Trust New Investigator Award Nov 2012 EMBO Young Investigator Program Oct 2010 Elected Fellow of Clare ... Curriculum vitae. Other activities 2020
  18. Carter lab dynactin prep from frozen porcine brains, using ...

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/2020_Carter_dynactin_brain_prep.docx
    28 Feb 2020: Get one new zip lock bag per brain, and open them so that they are easy to handle with dirty hands later on. ... Put brain in new zip lock bag and wash in PBS.
  19. rq5005

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/iucrjS20.pdf
    28 Jul 2020: L. D. & Kirshner, D. A. (1971). Nature New Biol. 231,.
  20. 31/10/2018 Carter lab TIRF microscopy Single Molecule Assay 5x ...

    https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/resources/protocols/2020_Carter_TIRF_protocol.docx
    28 Jan 2020: After 3 hours or so, make a new dilution. Consider also spinning the 250 µL stock if background is still high.
  21. FtsK in motion reveals its mechanism for double-stranded DNA…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK_Jean_2020_PNAS.pdf
    8 Jun 2020: J. Begg, S. J. Dewar, W. D. Donachie, A new Escherichia coli cell division gene, ftsK. ... Nucleic Acids Res. 32, 5260–5279 (2004). 28. J. Zivanov et al., New tools for automated high-resolution cryo-EM structure de-termination in RELION-3.
  22. The structure of human thyroglobulin

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TG_Nature2020.pdf
    31 Jan 2020: Struct. Biol. 180, 519–530 (2012). 35. Zivanov, J. et al. New tools for automated high-resolution cryo-EM structure determination in RELION-3.
  23. 16001658465475 1..36

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Collier_2020_elife-59560-v1.pdf
    15 Sep 2020: association with Smc1’s ATPase head and the coiled coil emerging from Smc3’s head creates a new.
  24. Clockology Survey Thank you for your interest in participating ...

    https://www2.mrc-lmb.cam.ac.uk/groups/oneill/wp-content/uploads/sites/24/Clockology-Survey-FINAL_14_07_2020_COMBINED.docx
    14 Jul 2020: The phase before the stimulus is plotted against the difference between the new phase and the old phase. ... Phase transition curve: a curve describing the relationship between the circadian phase at which a stimulus is applied and the resultant new
  25. 15919734904046 1..30

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020.pdf
    12 Jun 2020: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. †These authors contributed. equally to this work. Competing interest: See. page 25. Funding: See page 25. Received: 15 April 2020. Accepted: 26 May 2020. Published: 27 May 2020. Reviewing editor:
  26. 15955888524538 1..29

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020b.pdf
    24 Jul 2020: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. †These authors contributed. equally to this work. Competing interest: See. page 25. Funding: See page 25. Received: 15 June 2020. Accepted: 10 July 2020. Published: 13 July 2020. Reviewing editor:

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