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  2. Complete fly brain images at nanoscale resolution - MRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/complete-fly-brain-images-at-nanoscale-resolution/
    Thumbnail for Complete fly brain images at nanoscale resolution - MRC Laboratory of Molecular Biology 30 Jul 2018: A neuroscience milestone: a high-resolution digital snapshot of the adult fruit fly brain.  Researchers can now trace the path of any one neuron to any
  3. Regulation of DNA replication during early embryogenesis - MRC…

    https://www2.mrc-lmb.cam.ac.uk/regulation-of-dna-replication-during-early-embryogenesis/
    Thumbnail for Regulation of DNA replication during early embryogenesis - MRC Laboratory of Molecular Biology 9 Mar 2018: Published on. 9 March, 2018. Julian Sale from the LMB’s PNAC Division and collaborators from the Francis Crick Institute and the Department of Zoology have discovered and characterised a new
  4. Uncovering the structure of the serotonin receptor - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/uncovering-the-structure-of-the-serotonin-receptor/
    Thumbnail for Uncovering the structure of the serotonin receptor - MRC Laboratory of Molecular Biology 21 Jun 2018: Understanding the activation mechanism of the serotonin receptor and the mode of binding of a failed anti-migraine drug, donitripan, will hopefully aid the development of new and improved drugs. ... Comparing the new G. o. -receptor structure to other
  5. ‘Mini-brains’: understanding brain growth and disease - MRC…

    https://www2.mrc-lmb.cam.ac.uk/mini-brains-understanding-brain-growth-and-disease/
    Thumbnail for ‘Mini-brains’: understanding brain growth and disease - MRC Laboratory of Molecular Biology 30 Apr 2018: Philip Ball, science writer at The Guardian, has had a ‘mini-brain’ grown from a sample of skin from his arm. He talks to the LMB’s Madeline Lancaster,
  6. Decades of discovery set to revolutionise healthcare - MRC Laboratory …

    https://www2.mrc-lmb.cam.ac.uk/decades-of-discovery-set-to-revolutionise-healthcare/
    Thumbnail for Decades of discovery set to revolutionise healthcare - MRC Laboratory of Molecular Biology 1 Nov 2018: A summary of key milestones that show how discovery science has been translated into a novel technology set to revolutionise healthcare. The milestones
  7. Tau filament structures differ between neurodegenerative diseases -…

    https://www2.mrc-lmb.cam.ac.uk/tau-filament-structures-differ-between-neurodegenerative-diseases/
    Thumbnail for Tau filament structures differ between neurodegenerative diseases - MRC Laboratory of Molecular Biology 30 Aug 2018: These new structures show how tau folds in disease-specific ways, providing evidence for the hypothesis that different molecular structures of filamentous tau give rise to the diversity of symptoms between ... Comparison of the new structures of
  8. Melina Schuh writes about the turning point in her career: becoming a …

    https://www2.mrc-lmb.cam.ac.uk/melina-schuh-writes-about-turning-point-in-career/
    Thumbnail for Melina Schuh writes about the turning point in her career: becoming a group leader, and a mother - MRC Laboratory of Molecular Biology 31 Aug 2018: Melina Schuh, a former group leader in the LMB’s Cell Biology Division, has written about her experiences setting up her group at the LMB while also
  9. https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/acedrg-link…

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/acedrg-link-usage-notes.txt
    14 Mar 2018: Evaluating the script in Coot will provide a new menu item "Acedrg" Clicking on "Make Link with Link Dictionary from Acedrg" will create a new small dialog The bond order can
  10. Richard Henderson is guest on BBC Radio 4, 'The Life…

    https://www2.mrc-lmb.cam.ac.uk/richard-henderson-guest-bbc-radio-4-life-scientific/
    Thumbnail for Richard Henderson is guest on BBC Radio 4, 'The Life Scientific' - MRC Laboratory of Molecular Biology 13 Feb 2018: Richard Henderson talks to Jim Al-Khalili about his childhood, studies and career, specifically his journey working on the development of cryo-electron
  11. Melina Schuh awarded Biochemical Society Colworth Medal - MRC…

    https://www2.mrc-lmb.cam.ac.uk/melina-schuh-awarded-biochemical-society-colworth-medal/
    Thumbnail for Melina Schuh awarded Biochemical Society Colworth Medal - MRC Laboratory of Molecular Biology 23 Apr 2018: Melina Schuh has been awarded the Biochemical Society 2019 Colworth medal.  Melina investigates how chromosome segregation errors arise during the meiotic
  12. Rebecca Taylor discusses aging on BBC Radio Cambridgeshire - MRC…

    https://www2.mrc-lmb.cam.ac.uk/rebecca-taylor-discusses-aging-bbc-radio-cambridgeshire/
    Thumbnail for Rebecca Taylor discusses aging on BBC Radio Cambridgeshire - MRC Laboratory of Molecular Biology 22 Feb 2018: As part of a programme about aging, Rebecca Taylor from the LMB’s Neurobiology Division, talks to presenter Chris Mann about the science behind why we
  13. Magdalena Skipper appointed editor-in-chief at Nature - MRC…

    https://www2.mrc-lmb.cam.ac.uk/magdalena-skipper-appointed-editor-in-chief-at-nature/
    Thumbnail for Magdalena Skipper appointed editor-in-chief at Nature - MRC Laboratory of Molecular Biology 3 May 2018: Magdalena Skipper has been appointed editor-in-chief at Nature, becoming the first woman to hold the role in its almost 150-year history. More...
  14. How the earliest life on Earth may have replicated itself - MRC…

    https://www2.mrc-lmb.cam.ac.uk/how-the-earliest-life-on-earth-may-have-replicated-itself/
    Thumbnail for How the earliest life on Earth may have replicated itself - MRC Laboratory of Molecular Biology 16 May 2018: He then engineered the best version to be able to copy pieces of itself, and assemble them together into new full synthetic copies. ... This new synthetic biology of triplet based RNA replication might also have biotechnological applications, such as
  15. 2018 Francis Crick Lecture to be given by Gero Miesenböck - MRC…

    https://www2.mrc-lmb.cam.ac.uk/2018-francis-crick-lecture-to-be-given-by-gero-miesenbock/
    Thumbnail for 2018 Francis Crick Lecture to be given by Gero Miesenböck - MRC Laboratory of Molecular Biology 17 Oct 2018: In 2002, Gero established the principles of optogenetic control and thereby defined a new, now widely used, approach for probing the function of the nervous system. ... Gero studied medicine at the University of Innsbruck in his native Austria and did
  16. John Kendrew Lecture to be given by Jacques Dubochet - MRC Laboratory …

    https://www2.mrc-lmb.cam.ac.uk/john-kendrew-lecture-to-be-given-by-jacques-dubochet/
    Thumbnail for John Kendrew Lecture to be given by Jacques Dubochet - MRC Laboratory of Molecular Biology 19 Apr 2018: Jacques Dubochet will give the 2018 John Kendrew Lecture on Thursday 26th April at 4.00pm in the LMB’s Max Perutz Lecture Theatre.  The title of the
  17. Understanding how TRIM21 is regulated during viral infection - MRC…

    https://www2.mrc-lmb.cam.ac.uk/understanding-how-trim21-is-regulated-during-viral-infection/
    Thumbnail for Understanding how TRIM21 is regulated during viral infection - MRC Laboratory of Molecular Biology 19 Apr 2018: New work from Leo James’ group in the LMB’s PNAC Division has now revealed how TRIM21 is regulated so that it is only switched on at the right time. ... In addition, Leo’s lab has recently developed a new technique, ‘TrimAway’, which uses
  18. The legacy of Fred Sanger - 100 years on from 1918 - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/the-legacy-of-fred-sanger-100-years-on-from-1918/
    Thumbnail for The legacy of Fred Sanger - 100 years on from 1918 - MRC Laboratory of Molecular Biology 31 May 2018: This August marks the centenary of the birth of Fred Sanger, LMB alumnus and one of the most influential scientists of the twentieth century. By devising
  19. Science Weekly podcast: Growing mini-brains in the lab - MRC…

    https://www2.mrc-lmb.cam.ac.uk/science-weekly-podcast-growing-mini-brains-in-the-lab/
    Thumbnail for Science Weekly podcast: Growing mini-brains in the lab - MRC Laboratory of Molecular Biology 14 May 2018: In this week’s science podcast from The Guardian, Madeline Lancaster is interviewed to find out about the mini human brains that she and her group are
  20. Uncovering how alcohol-derived metabolites damage the genome of stem…

    https://www2.mrc-lmb.cam.ac.uk/uncovering-alcohol-derived-metabolites-damage-genome-stem-cells/
    Thumbnail for Uncovering how alcohol-derived metabolites damage the genome of stem cells - MRC Laboratory of Molecular Biology 4 Jan 2018: This new research has several implications for human health. It provides a simple explanation for how alcohol, which is a source of acetaldehyde, causes genetic damage and therefore acts as a ... In addition, the new insight into the function of p53 in
  21. Daniel McGillivray Brown. 3 February 1923-24 April 2012 - MRC…

    https://www2.mrc-lmb.cam.ac.uk/daniel-mcgillivray-brown-3-february-1923-24-april-2012/
    Thumbnail for Daniel McGillivray Brown. 3 February 1923-24 April 2012 - MRC Laboratory of Molecular Biology 21 Nov 2018: Dan Brown was a nucleic acids chemist of the highest order, beginning with pioneering work under Lord Alexander Todd in the 1950s at University of
  22. John Kendrew Lecture to be given by Xiaowei Zhuang - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/john-kendrew-lecture-to-be-given-by-xiaowei-zhuang/
    Thumbnail for John Kendrew Lecture to be given by Xiaowei Zhuang - MRC Laboratory of Molecular Biology 5 Jan 2018: Xiaowei Zhuang will give the 2017 John Kendrew Lecture on Monday 15th January 2018 at 4.00pm in the LMB’s Max Perutz Lecture Theatre. The title of the
  23. Minutes of the CCP4 Ligands Meeting March 2018

    https://www2.mrc-lmb.cam.ac.uk/coot/ligands/minutes-ccp4-ligands-meeting-march-2018.html
    23 Mar 2018: Briefly mentioned Coot's new N-linked carbohydrate builder. Note: we are using latest CCP4 expert version. ... But new users will be confused. AP: PE to investigate making some videos.
  24. Cambridge LIFE LAB project wins place in Europe’s largest public…

    https://www2.mrc-lmb.cam.ac.uk/cambridge-life-lab-project-wins-place-in-europes-largest-public-science-event/
    Thumbnail for Cambridge LIFE LAB project wins place in Europe’s largest public science event - MRC Laboratory of Molecular Biology 11 Jun 2018: LIFE LAB events are for everyone – we hope to meet and connect with many new people.”.
  25. Luca Jovine and Leonid Sazanov elected to EMBO membership - MRC…

    https://www2.mrc-lmb.cam.ac.uk/luca-jovine-and-leonid-sazanov-elected-to-embo-membership/
    Thumbnail for Luca Jovine and Leonid Sazanov elected to EMBO membership - MRC Laboratory of Molecular Biology 18 May 2018: LMB alumni Luca Jovine and Leonid Sazanov have been newly elected as members of the European Molecular Biology Organisation (EMBO), on the basis of their
  26. The legacy of Fred Sanger - 100 years on from 1918 - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/the-legacy-of-fred-sanger-100-years-on-from-1918-2/
    Thumbnail for The legacy of Fred Sanger - 100 years on from 1918 - MRC Laboratory of Molecular Biology 14 Aug 2018: August 2018 marks the centenary of the birth of Frederick (Fred) Sanger (1918–2013), one of the most influential scientists of the 20th century. Few
  27. Melina Schuh awarded a 2019 Gottfried Wilhelm Leibniz Prize - MRC…

    https://www2.mrc-lmb.cam.ac.uk/melina-schuh-awarded-a-2019-gottfried-wilhelm-leibniz-prize/
    Thumbnail for Melina Schuh awarded a 2019 Gottfried Wilhelm Leibniz Prize - MRC Laboratory of Molecular Biology 17 Dec 2018: The latest recipients of Germany’s most prestigious research prize, the Gottfried Wilhelm Leibniz Prize have been announced, and includes former LMB group
  28. Controlling actin polymerisation in clathrin mediated endocytosis -…

    https://www2.mrc-lmb.cam.ac.uk/controlling-actin-polymerisation-in-clathrin-mediated-endocytosis/
    Thumbnail for Controlling actin polymerisation in clathrin mediated endocytosis - MRC Laboratory of Molecular Biology 7 Jun 2018: The molecular details elucidated by this new research may open avenues to develop drugs to fight infections and to design complementary therapeutic strategies for some types of cancers.
  29. Reversing a decline in cellular transport in ageing nerve cells - MRC …

    https://www2.mrc-lmb.cam.ac.uk/reversing-a-decline-in-cellular-transport-in-ageing-nerve-cells/
    Thumbnail for Reversing a decline in cellular transport in ageing nerve cells - MRC Laboratory of Molecular Biology 29 Mar 2018: This work opens new avenues for attempting to manipulate transport in a therapeutic setting.
  30. How cells selectively enhance gene expression in response to stress - …

    https://www2.mrc-lmb.cam.ac.uk/how-cells-selectively-enhance-gene-expression-in-response-to-stress/
    Thumbnail for How cells selectively enhance gene expression in response to stress - MRC Laboratory of Molecular Biology 5 Sep 2018: In order to make new proteins, genes are first transcribed to produce messenger RNA (mRNA) molecules, that are then translated into proteins. ... This means that this new role for tRNAs in the control of gene expression could have a role in human disease.
  31. Bill Schafer elected Fellow of the Academy of Medical Sciences - MRC…

    https://www2.mrc-lmb.cam.ac.uk/bill-schafer-elected-fellow-of-the-academy-of-medical-sciences/
    Thumbnail for Bill Schafer elected Fellow of the Academy of Medical Sciences - MRC Laboratory of Molecular Biology 10 May 2018: Bill Schafer, group leader in the LMB’s Neurobiology Division, has been elected into the Fellowship of the Academy of Medical Sciences. The Academy
  32. Michel Goedert: on our best hope for tackling Alzheimer's disease …

    https://www2.mrc-lmb.cam.ac.uk/michel-goedert-our-best-hope-for-tackling-alzheimers-disease/
    Thumbnail for Michel Goedert: on our best hope for tackling Alzheimer's disease - MRC Laboratory of Molecular Biology 26 Mar 2018: Michel Goedert, winner of Brain Prize 2018, believes our best hope of fighting Alzheimer's disease lies in learning to predict who will get it and
  33. LMB student and postdoc prizes awarded to exceptional scientists -…

    https://www2.mrc-lmb.cam.ac.uk/lmb-student-and-postdoc-prizes-awarded-to-exceptional-scientists/
    Thumbnail for LMB student and postdoc prizes awarded to exceptional scientists - MRC Laboratory of Molecular Biology 17 Oct 2018: After being involved in the discovery of phospho-ubiquitin and its new conformational switch, Christina deciphered the molecular mechanism of parkin activation by phospho-ubiquitin, that parkin phosphorylation is important and
  34. The epic hunt for the place on Earth where life started - MRC…

    https://www2.mrc-lmb.cam.ac.uk/the-epic-hunt-for-the-place-on-earth-where-life-started/
    Thumbnail for The epic hunt for the place on Earth where life started - MRC Laboratory of Molecular Biology 21 Jun 2018: Working out how and where life began is one of the greatest puzzles to solve. The LMB’s Philipp Holliger and John Sutherland, and others, discuss their
  35. Wanda Kukulski awarded the Royal Microscopical Society’s Alan Agar…

    https://www2.mrc-lmb.cam.ac.uk/wanda-kukulski-awarded-the-royal-microscopical-societys-alan-agar-medal/
    Thumbnail for Wanda Kukulski awarded the Royal Microscopical Society’s Alan Agar Medal - MRC Laboratory of Molecular Biology 31 Aug 2018: Wanda Kukulski, group leader in the LMB’s Cell Biology Division, has been awarded the Royal Microscopical Society’s Alan Agar Medal for Electron
  36. CootCryoEMPractical-v2.md

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/CootCryoEMPractical-v2.md.html
    15 Aug 2018: Chain-refine (Shift E). We still have the wrong sequence, let’s apply the new one:.
  37. Sarah Teichmann awarded the Genetics Society's 2018 Mary Lyon…

    https://www2.mrc-lmb.cam.ac.uk/sarah-teichmann-awarded-genetics-societys-2018-mary-lyon-medal/
    Thumbnail for Sarah Teichmann awarded the Genetics Society's 2018 Mary Lyon Medal - MRC Laboratory of Molecular Biology 31 Jan 2018: Sarah Teichamnn has received the Genetics Society’s prestigious Mary Lyon Medal 2018 for “outstanding research” in understanding how the immune system
  38. Dr Varodom Charoensawan wins the 2018 FAOBMB Young Scientist Award -…

    https://www2.mrc-lmb.cam.ac.uk/dr-varodom-charoensawan-wins-2018-faobmb-young-scientist-award/
    Thumbnail for Dr Varodom Charoensawan wins the 2018 FAOBMB Young Scientist Award - MRC Laboratory of Molecular Biology 2 Feb 2018: Dr Varodom Charoensawan, former PhD student in the LMB’s Structural Studies Division, has been awarded the FAOBMB Young Scientist Award for his work on
  39. Three-dimensional representation of motor space in the brain - MRC…

    https://www2.mrc-lmb.cam.ac.uk/three-dimensional-representation-of-motor-space-in-the-brain/
    Thumbnail for Three-dimensional representation of motor space in the brain - MRC Laboratory of Molecular Biology 17 May 2018: These results provide the first evidence of a three-dimensional representation of motor space in the superior colliculus and give new insights into the mechanisms underlying the control of spatially-targeted
  40. A parliamentary lab meeting - Daniel Zeichner MP visits the LMB - MRC …

    https://www2.mrc-lmb.cam.ac.uk/a-parliamentary-lab-meeting-daniel-zeichner-mp-visits-the-lmb/
    Thumbnail for A parliamentary lab meeting - Daniel Zeichner MP visits the LMB - MRC Laboratory of Molecular Biology 14 Jun 2018: Glenn Masson, postdoc in the LMB’s PNAC Division, took part in this year’s Royal Society Parliamentary Pairing Scheme. Read Glenn’s blog to find out more
  41. Susan Shao and Tanmay Bharat appointed as 2018 Vallee Scholars - MRC…

    https://www2.mrc-lmb.cam.ac.uk/susan-shao-and-tanmay-bharat-appointed-as-2018-vallee-scholars/
    Thumbnail for Susan Shao and Tanmay Bharat appointed as 2018 Vallee Scholars - MRC Laboratory of Molecular Biology 3 Oct 2018: LMB alumni Susan Shao and Tanmay Bharat are two of the five scientists to be awarded prestigious Vallee Scholarships in 2018. The Vallee Scholars program
  42. LMB’s Challenge Project with Cambridge Academy for Science and…

    https://www2.mrc-lmb.cam.ac.uk/lmbs-challenge-project-with-cambridge-academy-for-science-and-technology/
    Thumbnail for LMB’s Challenge Project with Cambridge Academy for Science and Technology - MRC Laboratory of Molecular Biology 23 Mar 2018: Theo, one of the students who participated in the Challenge Project, said the project “opened up new career ideas and broadened my horizons”.
  43. Silent tuberculosis is less common than had been widely thought - MRC …

    https://www2.mrc-lmb.cam.ac.uk/silent-tuberculosis-is-less-common-than-had-been-widely-thought/
    Thumbnail for Silent tuberculosis is less common than had been widely thought - MRC Laboratory of Molecular Biology 24 Sep 2018: A study by Lalita Ramakrishnan, from the University of Cambridge Molecular Immunity Unit based in the LMB, has found that most people who fall seriously
  44. The winner of the 2018 LMB’s schools Science Image Award is… - MRC…

    https://www2.mrc-lmb.cam.ac.uk/the-winner-of-the-2018-lmbs-schools-science-image-award-is/
    Thumbnail for The winner of the 2018 LMB’s schools Science Image Award is… - MRC Laboratory of Molecular Biology 13 Jul 2018: Thirteen primary schools from Cambridge and the surrounding area have participated in this year’s Science Image Award.  The competition, part of the LMB’s
  45. Ana Casañal awarded Biochemical Society Early Career Research Award.…

    https://www2.mrc-lmb.cam.ac.uk/ana-casanal-awarded-biochemical-society-early-career-research-award/
    Thumbnail for Ana Casañal awarded Biochemical Society Early Career Research Award. - MRC Laboratory of Molecular Biology 4 Apr 2018: Ana Casañal from the LMB’s Structural Studies Division has been awarded the prestigious Biochemical Society Early Career Research Award 2019 for Genes.
  46. REFMAC5 Tutorial - Part 2

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/refmac_tutorial/files/part_2.html
    23 Jun 2018: Show Me This. A new job will be created. The main inputs may already be populated with data from a previous job, in which case select "No" from the "Use data ... This will create a new job, pre-populated with the inputs from the previous job.
  47. LMB showcases the diversity of science at the Cambridge Science…

    https://www2.mrc-lmb.cam.ac.uk/lmb-showcases-the-diversity-of-science-at-the-cambridge-science-festival/
    Thumbnail for LMB showcases the diversity of science at the Cambridge Science Festival - MRC Laboratory of Molecular Biology 28 Mar 2018: New for the 2018 Guildhall event, members of the public could pop into the special science booth to chat to the scientists about their research. ... His talk looked at the exciting work in the field of structural biology, tracing the beginnings of the
  48. Johannes Kohl wins the 2018 Eppendorf & Science Prize for…

    https://www2.mrc-lmb.cam.ac.uk/johannes-kohl-wins-the-2018-eppendorf-science-prize-for-neurobiology/
    Thumbnail for Johannes Kohl wins the 2018 Eppendorf & Science Prize for Neurobiology - MRC Laboratory of Molecular Biology 17 Oct 2018: Johannes Kohl, a former PhD student from Greg Jefferis’ group in the LMB’s Neurobiology division, is the grand prize winner in The Eppendorf & Science
  49. From Backbench to Lab Bench: LMB welcomes visitors from Westminster - …

    https://www2.mrc-lmb.cam.ac.uk/from-backbench-to-lab-bench-lmb-welcomes-visitors-from-westminster/
    Thumbnail for From Backbench to Lab Bench: LMB welcomes visitors from Westminster - MRC Laboratory of Molecular Biology 17 Apr 2018: Daniel Zeichner MP for Cambridge, and Nancy Bailey and Rebecca Nohl from the Government Office for Science, swapped policy and debate for lab coats and
  50. Alcohol can cause irreversible genetic damage to stem cells, says…

    https://www2.mrc-lmb.cam.ac.uk/alcohol-can-cause-irreversible-genetic-damage-stem-cells-says-study/
    Thumbnail for Alcohol can cause irreversible genetic damage to stem cells, says study - MRC Laboratory of Molecular Biology 5 Jan 2018: Link between drinking and cancer clarified by study - led by KJ Patel’s group in the LMB’s PNAC Division - which indicates alcohol causes cancer by
  51. Making the undruggable druggable: the first platform to discover…

    https://www2.mrc-lmb.cam.ac.uk/making-the-undruggable-druggable-the-first-platform-to-discover-selective-phosphatase-inhibitors/
    Thumbnail for Making the undruggable druggable: the first platform to discover selective phosphatase inhibitors - MRC Laboratory of Molecular Biology 26 Jul 2018: New method identifies a selective inhibitor of PPP1R15B, a potential target for Huntington’s disease. ... This novel approach may pave the way to a new therapeutic strategy for such diseases.

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