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  2. LMB researchers are taking part in LifeLab with events around…

    https://www2.mrc-lmb.cam.ac.uk/lmb-researchers-are-taking-part-in-lifelab-with-events-around-cambridgeshire-on-friday-28th-and-saturday-29th-september/
    Thumbnail for LMB researchers are taking part in LifeLab with events around Cambridgeshire on Friday 28th and Saturday 29th September - MRC Laboratory of Molecular Biology 20 Sep 2018: LMB researchers are helping to transform parts of Cambridgeshire into centres of discovery with hands-on, family-friendly activities in shopping centres,
  3. Instinctive and learned responses to smells are controlled by a…

    https://www2.mrc-lmb.cam.ac.uk/instinctive-and-learned-responses-to-smells-are-controlled-by-a-single-brain-circuit-in-flies/
    Thumbnail for Instinctive and learned responses to smells are controlled by a single brain circuit in flies - MRC Laboratory of Molecular Biology 20 Sep 2018: As well as having instinctive responses to their environment, nearly all animals can learn to associate particular sights, smells, or sounds with rewards
  4. Fabrice Gorrec has been shortlisted for the Researcher of the Year…

    https://www2.mrc-lmb.cam.ac.uk/fabrice-gorrec-has-been-shortlisted-for-the-researcher-of-the-year-category-at-the-cambridge-independent-science-and-technology-awards-2018/
    Thumbnail for Fabrice Gorrec has been shortlisted for the Researcher of the Year category at the Cambridge Independent Science and Technology Awards 2018 - MRC Laboratory of Molecular Biology 17 Sep 2018: Fabrice Gorrec, from the LMB’s crystallisation facility, is a finalist in the newly introduced Researcher of the Year category at the Cambridge
  5. John Sulston (1942-2018): looking back at the pioneering life and…

    https://www2.mrc-lmb.cam.ac.uk/john-sulston-1942-2018-looking-back-at-the-pioneering-life-and-work-of-this-nobel-prize-winning-scientist/
    Thumbnail for John Sulston (1942-2018): looking back at the pioneering life and work of this Nobel Prize-winning scientist - MRC Laboratory of Molecular Biology 21 Mar 2018: Nature looks back at the life and work of John Sulston, from his time investigating cell fate, lineage and the genetics of C. elegans at the LMB, to his
  6. Computational biologist M. Madan Babu is named Life Sciences Laureate …

    https://www2.mrc-lmb.cam.ac.uk/computational-biologist-m-madan-babu-is-named-life-sciences-laureate-at-the-2018-blavatnik-awards-for-young-scientists/
    Thumbnail for Computational biologist M. Madan Babu is named Life Sciences Laureate at the 2018 Blavatnik Awards for Young Scientists - MRC Laboratory of Molecular Biology 23 Mar 2018: In the first year that the Blavatnik Awards for Young Scientists have been extended to the UK, M. Madan Babu is named Life Sciences Laureate for his work
  7. ProSHADE: ProSHADE_internal::ProSHADE_compareOneAgainstAll Class…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d3/d79/class_pro_s_h_a_d_e__internal_1_1_pro_s_h_a_d_e__compare_one_against_all.html
    1 Nov 2018: releasing the old intertwined vector and returning a new vector of aligned structures.
  8. ProSHADE: src/proshade/ProSHADE_spharmonickit.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d8/dd5/_pro_s_h_a_d_e__spharmonickit_8cpp_source.html
    1 Nov 2018: 222 //======================================== Initialise internal values ( and allocate memory ). 223 this->_shellMappedData = new double[this->_noShellsWithData];. ... semiNaiveTableSpace = new double [static_cast<unsigned int> (
  9. Name: than you think! SafetyOur worms, and the bacteria ...

    https://www2.mrc-lmb.cam.ac.uk/groups/worms/download/Worms-are-Cleverer-workbook.pdf
    18 Jan 2018: For example, we can introduce new DNA (i.e. make transgenic animals), to express fluorescent proteins in our cells of interest, or we can silence genes to find out what they
  10. Coot: Model-building tools for Molecular Graphics

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cshl-2018.pdf
    24 Oct 2018: 4 PHE Rotamers. Previous. TraditionalBackrub. Helix-Building. Alpha Helix Placement. Scenario: Looking at a new map, not built with automatic tools: “I can see that there’s a helix here - ... Chemical Features. GUI Updates. Map Properties. The New
  11. ProSHADE: src/proshade/ProSHADE_descriptors.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/df/d91/_pro_s_h_a_d_e__descriptors_8cpp_source.html
    1 Nov 2018: 251 for ( unsigned int shIt = 0; shIt < this->_noShellsWithData; shIt++ ). 252 {. 253 this->_rrpMatrices[bwIt][shIt] = new double [this->_noShellsWithData];. ... lIter++ ). 502 {. 503 this->_trSigmaEMatrix[bandUsageIndex][lIter] = new std::array<double,2>
  12. Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Oct-TF.pdf
    8 Oct 2018: Outline. New Tools for Cryo-EM reconstructions Context (experiments) Large-scale movement (morph and jiggle) Alpha Helix fitting Restraints Refinement Back-rub Rotamers cis-peptides Filaments New visualizations. ... Hydrogen Density? New/Bleeding
  13. mbar-v2

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/mbar-v2.pdf
    31 Aug 2018: proceed. 2.2.3.The new waters have been added to chain D, and it is important to inspect them and make sure that they have all been added in appropriate
  14. Coot: Model-building tools for Molecular Graphics

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/bgu/coot-2018-bgu.pdf
    22 Feb 2018: 4 PHE Rotamers. Previous. TraditionalBackrub. Helix-Building. Alpha Helix Placement. Scenario: Looking at a new map, not built with automatic tools: “I can see that there’s a helix here - ... Why are they different? or new NCS Differences graph.
  15. Cryo-EM reconstruction of AlfA from Bacillus subtilis reveals the…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/AlfA2018.pdf
    20 Mar 2018: The antiparallel orientation of the. filaments is necessary to ensure that when new protomers areadded to the spindle, it grows in opposite directions and pushes theplasmid copies apart (23). ... FASEB J 9:167–174.36. Krissinel E, Henrick K (2004)
  16. Interactive Tools forCryo-EM Map Fitting Paul EmsleyMRC Laboratory of …

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-June-PSI.pdf
    19 Jun 2018: Yeast Mitochondrial Large Ribosomal Subunit. 19/06/18. New Ribosome Components. blue: conservedred: found in bothyellow: yeast only. ... Lots to see at 4 rmsd. Alpha Helix Placement. Scenario: Looking at a new map, not built with automatic tools: “I
  17. Coot Tools for Cryo-EM Paul EmsleyMRC Laboratory of Molecular ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/coot-cryoEM-2018-Aug-Stockholm.pdf
    15 Aug 2018: Lots to see at 4 rmsd. Alpha Helix Placement. Scenario: Looking at a new map, not built with automatic tools: “I can see that there’s a helix here - build ... New/Bleeding Edge/Still-in-Development. The New Ramachandran Plot. EMD-0144:1.65 Å
  18. ProSHADE: ProSHADE_internal::ProSHADE_data Class Reference

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d1/dee/class_pro_s_h_a_d_e__internal_1_1_pro_s_h_a_d_e__data.html
    1 Nov 2018: For each box passing the tests, it then creates a new ProSHADE_data object in a vector of such objects it returns.
  19. ProSHADE: src/proshade/ProSHADE.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d4/d4f/_pro_s_h_a_d_e_8cpp_source.html
    1 Nov 2018: 1365 ProSHADE_internal::ProSHADE_distances db = new ProSHADE_internal::ProSHADE_distances ( setUp );. 1366 delete db;.
  20. Prokaryotic cytoskeletons: protein filaments organizing small cells

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro.2017.153.pdf
    18 Jan 2018: as well as entirely new classes of filaments16–18, leading to an expanded concept of what a cytoskeleton is (BOX 1). ... In many rod‑shaped bacteria, dynamic MreB filaments control the synthesis of a new cell wall to maintain shape.
  21. Journal of Visualized Experiments www.jove.com Copyright © 2018…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/JOVE2018.pdf
    19 Apr 2018: protein droplets (each row now requires 8 new microsyringesto avoid cross-contamination).
  22. mbar-v2

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/model-building-and-refinement-v2.pdf
    31 Aug 2018: proceed. 2.2.3.The new waters have been added to chain D, and it is important to inspect them and make sure that they have all been added in appropriate
  23. ProSHADE: src/proshade/ProSHADE_clipper.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d9/d66/_pro_s_h_a_d_e__clipper_8cpp_source.html
    1 Nov 2018: 100 clipper::mmdb::CMMDBManager mfile = new clipper::mmdb::CMMDBManager ( );. 101 if ( mfile->ReadCoorFile ( this->_inputFileName.c_str() ) ). 102 {. 103 std::cerr << "! ProSHADE ERROR! Cannot read file: " << this->_inputFileName.c_str() <<
  24. ProSHADE: src/proshade/ProSHADE_SO3transform.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d7/db2/_pro_s_h_a_d_e___s_o3transform_8cpp_source.html
    1 Nov 2018: 0 ) 48 this->_bandwidthLimit ) );. 142 this->_so3Workspace3 = new double [static_cast<unsigned int> ( 24 this->_bandwidthLimit 2 pow( static_cast<double> ( this->_bandwidthLimit ), 2.0 ) )];. 143. ... sizeof ( fftw_complex ) 14 pow( static_cast<double> (
  25. ProSHADE: src/proshade/ProSHADE_saveLoad.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d0/df1/_pro_s_h_a_d_e__save_load_8cpp_source.html
    1 Nov 2018: 622 ProSHADE_data one = new ProSHADE_data ();. 623. ... 877 ProSHADE_data one = new ProSHADE_data ();. 878.
  26. ProSHADE: src/proshade/ProSHADE_internal.cpp Source File

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/proshade/doxygen/d9/dc4/_pro_s_h_a_d_e__internal_8cpp_source.html
    1 Nov 2018: nullptr ). 212 {. 213 this->_densityMapMap = new float[(copyFrom->_maxMapU1) (copyFrom->_maxMapV1) (copyFrom->_maxMapW1)];. ... nullptr ). 232 {. 233 this->_densityMapCor = new double[(copyFrom->_maxMapU1) (copyFrom->_maxMapV1) (copyFrom->_maxMapW1)];.
  27. 15211199233993 1..45

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreBHussain2018.pdf
    15 Mar 2018: As the. motions of the Rod complexes reflect the insertion of new cell wall, their circumferential motions. ... along a perfectly ordered template. As MreB movement reflects the insertion of new glycan strands,.
  28. The ER membrane protein complex is a transmembrane domain insertase

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf
    27 Jan 2018: Constructs for translation in the PURE system (28) were based on the T7-based PURExpress plasmid provided by New England Biolabs.

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