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New drug target for asthma - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/new-drug-target-asthma/13 Oct 2016: Search this website. New drug target for asthma. New drug target for asthma. ... Published on. 13 October, 2016. A new therapeutic target for inflammatory diseases such as asthma and autoimmune disorders has been identified by scientists at the Wellcome -
NBLAST – a new online tool to compare neurons - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/nblast-new-online-tool-compare-neurons/20 Jul 2016: 20 July, 2016. Researchers in Greg Jefferis’s group in the LMB’s Neurobiology Division have developed a new online tool to analyse images of neurons. ... NBLAST is already proving useful in fly brain research to identify neuron types, organize large -
New hypothesis for the formation of macropinocytic cups - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-hypothesis-formation-macropinocytic-cups/14 Dec 2016: New hypothesis for the formation of macropinocytic cups. Published on. 14 December, 2016. ... the USA and Robert Insall at the Beatson Institute in Glasgow, has resulted in the formation of a new hypothesis for how these cups form. -
New microscope lens: top ten breakthroughs - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-microscope-lens-top-ten-breakthroughs/13 Dec 2016: Search this website. New microscope lens: top ten breakthroughs. New microscope lens: top ten breakthroughs. ... Ten Breakthroughs of 2016, for creating a new microscope lens that offers the unique combination of a large field of view with high resolution -
Epigenetic instability
https://www2.mrc-lmb.cam.ac.uk/groups/jes/epigeninst.html2 Sep 2016: Thus parental H3/4 tetramers are interspersed with newly synthesised H3/4. Most of the time, the old and new proteins are not mixed within the same nucleosome. ... In DT40 cells lacking Rev1, certain normally repressed genes containing G quadruplex DNA -
LMB welcomes Joseph Yeeles as new Group Leader - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-joseph-yeeles-new-group-leader/11 Jul 2016: LMB welcomes Joseph Yeeles as new Group Leader. Published on. 11 July, 2016. ... Our development of a reconstituted eukaryotic replication system provides exciting new opportunities to investigate mechanisms of chromosome replication in ways that were -
New insights into the mechanism of ubiquitin chain cleavage - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-insights-mechanism-ubiquitin-chain-cleavage/13 Oct 2016: This has given unprecedented insight into the catalytic mechanism of a DUB and revealed a new mechanism of how ubiquitin chains can be cleaved. ... The new understanding of the catalytic process in deubiquitinases will become a key reference point for -
LMB welcomes Emmanuel Derivery as new Group Leader - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-emmanuel-derivery-new-group-leader/17 Nov 2016: Search this website. LMB welcomes Emmanuel Derivery as new Group Leader. ... LMB welcomes Emmanuel Derivery as new Group Leader. Published on. 17 November, 2016. -
New technologies enable systematic recoding of genomes - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-technologies-enable-systematic-recoding-genomes/24 Oct 2016: Search this website. New technologies enable systematic recoding of genomes. New technologies enable systematic recoding of genomes. ... Using these new techniques they attempted systematic recoding of the genomic sequence in an essential operon using -
Artificial DNA could build new generation of cancer drugs - MRC…
https://www2.mrc-lmb.cam.ac.uk/artificial-dna-build-new-generation-cancer-drugs/12 Apr 2016: Search this website. Artificial DNA could build new generation of cancer drugs. ... Artificial DNA could build new generation of cancer drugs. Published on. -
Cryo-EM sheds new light on the spliceosome activation process - MRC…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-sheds-new-light-on-the-spliceosome-activation-process/1 Feb 2016: Search this website. Cryo-EM sheds new light on the spliceosome activation process. ... Cryo-EM sheds new light on the spliceosome activation process. Published on. -
Structural insight offers potential for new anti-malarial treatment - …
https://www2.mrc-lmb.cam.ac.uk/structural-insight-offers-potential-for-new-anti-malarial-treatment/11 Feb 2016: Structural insight offers potential for new anti-malarial treatment. Published on. 11 February, 2016. . ... falciparum proteasome and used this information to design a new compound with promising anti-malarial properties. -
Suffrage Science Scheme Award for Lori Passmore - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/suffrage-science-scheme-award-lori-passmore/9 Mar 2016: She is also developing new methods with cryo-EM to help determine protein structure, including the development of new specimen grids made of pure gold, that improve the quality of -
Recovering stalled ribosomes - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/recovering-stalled-ribosomes/8 Dec 2016: Now researchers in the LMB’s Structural Studies and Cell Biology divisions have used electron cryomicroscopy (cryo-EM) to reveal new insights into these mechanisms. ... It is hoped that these new insights will enrich our understanding of the -
From Parkinson’s Disease to ubiquitin - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/parkinsons-disease-ubiquitin/29 Mar 2016: LMB, on a journey to cast surprising new light on the universal cellular ubiquitin modification system (page 9) More…. -
Structure of the catalytic spliceosome - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/structure-catalytic-spliceosome/26 Jul 2016: This has provided important mechanistic insights into RNA-based splicing catalysis. It has consolidated nearly three decades of biochemistry and genetics on the spliceosome and indicates new research directions to be -
Soft Landings Project: The MRC LMB - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/soft-landings-project-mrc-lmb/16 Jun 2016: Published on. 16 June, 2016. Details of the Soft Landings project for the new LMB building, including a summary of the building’s special features, the design and construction process and -
Interview with Richard Henderson - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/interview-richard-henderson/27 Jun 2016: The winner of the Copley Medal talks structural biology, fixing cars and sleeping soundly. More... -
Entertaining the crowds at Soapbox Science, Cambridge - MRC…
https://www2.mrc-lmb.cam.ac.uk/entertaining-crowds-soapbox-science-cambridge/6 Jul 2016: The LMB’s Danielle Mersch and Nicola Smyllie along with other leading female scientists from the region took to their soapboxes on Saturday 2nd July in -
Knighthood for Richard Treisman - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/knighthood-richard-treisman/13 Jun 2016: Richard Treisman, biochemist, molecular biologist and Research Director at the Francis Crick Institute, has been knighted in the Queen's Birthday Honours
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