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23 Nov 2004: new computational model from Scott Bornheimer, Shankar Subra-maniam, and colleagues (University of California, San Diego, CA)predicts how the GTPase cycle operates in one of several modes.

2 Feb 2004: www.sciencemag.org SCIENCE VOL 303 23 JANUARY 2004 479. One of the basic needs of any growingcell is the ability to remodel the lipidmembranes that both surround the. cell and make up its intracellular organelles.At any point in time, a multitude of

17 Mar 2004: An important new structure suggests the BAR domainis a membrane-binding module that can both produceand sense membrane curvature. ... 2Department of Physiology and Biophysics, Health ScienceCenter, State University of New York at Stony Brook, StonyBrook,

3 Dec 2004: Theformation of a new vesicle is thought to be driven by both thepolymerization of the coat protein clathrin into a cage-like structureand the selection/modification of membrane lipids5,6. ... solved in the absence of a lipid head group14 (Fig. 2a,

3 Dec 2004: Theformation of a new vesicle is thought to be driven by both thepolymerization of the coat protein clathrin into a cage-like structureand the selection/modification of membrane lipids5,6. ... solved in the absence of a lipid head group14 (Fig. 2a,

3 Dec 2004: 17,4943 (1998). 35. A. G. W. Leslie, in Joint CCP4 and ESF-EACMB News-letter on Protein Crystallography No.

6 Oct 2004: 2001). Rap1 signal-ling: adhering to new models. Nat. Rev. Mol. Cell Biol.

3 Dec 2004: 17,4943 (1998). 35. A. G. W. Leslie, in Joint CCP4 and ESF-EACMB News-letter on Protein Crystallography No.

3 Dec 2004: 17,4943 (1998). 35. A. G. W. Leslie, in Joint CCP4 and ESF-EACMB News-letter on Protein Crystallography No.

23 Nov 2004: X-ray Crystallography and NMR (Yale Univ. Press,New Haven, CT, 1993). 24.

29 Dec 2004: In addition, little new information regarding cotransport regulation in avian erythrocytes can come from this approach. ... Unlabeled bume- tanide and furosemide was the gift of Hoechst Pharmaceuticals (New Jersey).

1 May 2004: The SulA fold is related to a fragment of RecA, but this seems accidental andprobably only shows how nature reuses successful designs for new purposes. ... For GFP labeling, new genetic tools in mollicutes must be devel-oped for that purpose.

30 Jun 2004: Molecular Microbiology (2004). 53. (2), 419–432 doi:10.1111/j.1365-2958.2004.04133.x. 2004 Blackwell Publishing Ltd. Blackwell Science, LtdOxford, UKMMIMolecular Microbiology0950-382XBlackwell Publishing Ltd, 2004? 2004. 53. 2419432. Original

20 Sep 2004: anaphase. as synchronously as cells that had expressed it only new bridges at any period from the completion of DNA. ... dissocia-ates new links between sister chromatids.tion of Smc1 and Smc3 hinge domains or when Smc1and Smc3 heads are not connected by

2 Jun 2004: Current address: Vion Pharmaceuticals, New Haven, CT 06511. Current address: University of Kentucky College of Medicine,.

19 Nov 2004: 39. Brunger, A.T. et al. Crystallography & NMR system: a new software suite for macromo-lecular structure determination.

24 Sep 2004: Section 1734 solely toindicate this fact. The atomic coordinates and structure factors (code 1uzx) have beendeposited in the Protein Data Bank, Research Collaboratory for Struc-tural Bioinformatics, Rutgers University, New Brunswick,

23 Nov 2004: Indi- 11. Corvera, S. (2001). Phosphatidylinositol 3-kinase and the controlrect immunofluorescence was performed on cells permeabilized of endosome dynamics: New players defined by structural mo-with 0.1% Triton

23 Nov 2004: C., Blondeau, F., and McPherson, P. S.(2003). Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif. ... P.,and De Camilli, P. (1999). The epsins define a family of proteins that interact withcomponents of the

23 Nov 2004: W, FxDxF, WVxF and a new FxxFxxL motif), we can now. ... but a number of new ligands including the HIV-1 Rev inter-.

2 Feb 2004: Membrane transport between compartments in eukary-otic cells requires proteins that allow the budding andSCISSION of nascent cargo vesicles from one compartmentand their targeting and fusion with another. Just asSNARES are proposed to be essential

15 Jan 2004: Therefore, we employed two new ap-proaches. First, we took advantage of the ability of PTA todifferentially precipitate PrPSc while leaving PrPC in the super-natant fraction. ... ity of this model system, until now. Selective precipitation ofPrPSc(P101L)

29 Dec 2004: G., eds) Vol. 17, pp. 312-362, Academic Press, New York. Beam, K.

21 Dec 2004: Treatment of cell lysateswith peptide:N-glycosidase and endoglycosidase H (both from New EnglandBiolabs, Beverly, MA) was performed as recommended by the manufacturer.Pulse labeling was performed in six-well dishes

6 Dec 2004: A new mech-anism is shown whereby dynamin causes fission of the intact fusedvesicle before collapse and intermixing with the plasma membrane.v-SNARE, vesicle SNARE; t-SNARE, target SNARE.

8 Nov 2004: Protection from cytosolic prion protein toxicityby modulation of protein translocation. Neena S Rane, Jesse L Yonkovich andRamanujan S Hegde. Cell Biology and Metabolism Branch, NICHD, National Institutesof Health, Bethesda, MD, USA. Failure to

15 Apr 2004: This ap-proach was subsequently exploited to provide new insightsinto both the composition and organizational state of thetranslocon during its functional cycle in cells. ... Pactamycin also inhibits new proteinsynthesis within 5 min, but as expected for