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28 Jun 2008: Search this website. DNA pioneers to get new £197m lab. DNA pioneers to get new £197m lab. ... The new facility will enable research into areas such as neurobiology.”Primary Sidebar.

6 Feb 2008: 3. , 1 mM NaHPO, pH7.0. NS (New salts). 20 mM KCl, 20 mM NaCl, 1 mM CaCl. ... protein. DDB numbers. old gene name. new gene name. AP1 g adaptin.

28 Jul 2008: 1987-1990 Dundee University, Scotland. Ph.D in Neurochemistry. Thesis title ÔGlutamate neurotransmitter: new insights into the release mechanismÕ.

26 Oct 2008: The new lower specimen translation plate has the same overall dimensions as the original one (fig. ... The new specimen cartridge has a 2”-tapered copper body with a stainless steel sleeve and pin, shaped as for the original cartridge to permit.

9 Dec 2008: the Vps26 domain is present in all eukaryotes—which is good news for plants because they were hitherto thought to completely lack arrestins. ... Trends Biochem Sci 28: 598–603. lefkowitz rJ, rajagopal K, Whalen EJ (2006) new roles for β-arrestins in

21 Nov 2008: redox perturbations), thereby providing a new tool for exploring the ER. ... This new molecular tool can now be combined with the vast collections of yeast strains (deletion, hypomorphic, overexpression, and other mutations) to reveal previously

18 Dec 2008: The title. CopyrightAmerican Association for the Advancement of Science, 1200 New York Avenue NW, Washington, DC 20005.

4 Aug 2008: ParM filaments while allowing entry of new ATP-bound. monomers. We propose a processive mechanism by which. ... The binding of a new subunit. induces ATP hydrolysis in the previous subunit of the proto-.

17 Sep 2008: The adaptor protein ParR has ‘formin-like activity’, meaning. t actively participates in the addition of new ParM subunits to thend.

16 Oct 2008: Throughiterative chemical synthesis, X-ray crystallography and kinome-level biochemical profiling, we identified compounds that inhibit aspectrum of new target combinations in these two families. ... The progress of this chemistry. was guided by testing

30 May 2008: Supporting Information Available: Detailed experimental section,synthesis, and spectral characterization of new compounds.

30 May 2008: Asymmetric distribution of pause transfer sequences in apolipoprotein B-I00. Maryann H. Kivlen, Cynthia A. Dorsey, Vishwanath R. Lingappa,'yt and Ramanujan S. Hegde Departments of Physiology and Medicine, University. of California, San Francisco,

22 Jul 2008: The new structure in-. dicates that a single copy of Sec61 is bound to the nontranslating. ... plexes bound to ribosomes. The TRAP ComplexOur new structure shows that one copy of the TRAP complex is.

18 Sep 2008: Clearly, new in situ methodologies for measuring translocation. will be needed to assess this effect of PrPSc on a finer scale. ... Figure 4D). Furthermore, steady-state Ifn-PrP expression levels. in whole brain, and even neurons cultured from transgenic

4 Mar 2008: Structural and mutational analysis of the cell divisionprotein FtsQ. Fusinita van den Ent,1 Thessa M. F. Vinkenvleugel,2. Alice Ind,1 Philip West,1 Dmitry Veprintsev,1. Nanne Nanninga,2 Tanneke den Blaauwen2 andJan Löwe11MRC-LMB, Hills Road,

6 Mar 2008: Here we use. xvi. automated methods to automatically detect these activities, which rely in part on a new method. ... These new. methods have made it possible to reliably detect events that are time-consuming and laborious to.

16 Aug 2008: The new. high-resolution structure confirms that FtsKg is a winged helix. ... conformation, though the new high-resolution crystal structure. shows that the two strands do not have a regular b sheet hydro-.

4 Aug 2008: tubules with the aid of new microtubule-associated proteins. (MAPs), some of which may be related to tektins [49,50]. ... has grown longer through gene duplication. It is likely that many such questions will be answered as new.

25 Sep 2008: Therefore, genetic mutations thatimpart a new or aberrant property on the protein to causecellular dysfunction are termed gain-of-function (GOF)diseases.

18 Oct 2008: essential for induction of synaptic long-term depression. (LTD) (9,10) as well as for a new form of cerebellar synaptic. ... we present data providing new insight into the molecular. mechanisms controlling the activity of the PICK1 BAR.

22 May 2008: These blebs are reversible, and re-versal requires actin polymerization into thesesites to provide new membrane-cytoskeletonlinkage. ... Upon recovery fromhypotonic stretch, cells shrink and new invagi-nations from the membrane are formed (133).The

10 Jun 2008: suggested that goa-1 defined a new pathway, independent of the ones activated by flp-1 and.

28 Nov 2008: context of our findings, study of Cla-thrin-independent endocytic pathways will reveal new layersof complexity underlying lipid and protein cargo selection, ap-propriate intracellular trafficking of endocytic membranes, andthe mechanisms

16 Jul 2008: more generally, led to new insights into the deter-minants for QC of GPI-anchored proteins in the ER. ... All enzymes for cloning were ob-tained from New England Biolabs (Beverly, MA) with the exception of Pfupolymerase, which was from Stratagene (La

13 Dec 2008: The Hydrophobic Insertion Mechanism of Membrane CurvatureGeneration by Proteins. Felix Campelo,y Harvey T. McMahon,z and Michael M. KozlovDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv,

3 Sep 2008: to prepare grids for EM analysis. If no filaments were visible in this initial examination, the protein stock was incubated at 4C for 3–4 days and new EM.

22 Jul 2008: Although the study of essential and constitutive facets of translocation has required simple and highly robust model systems, the study of regulation will probably necessitate more complex substrates and potentially new