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2 Apr 2024: Search this website. Rising Talent Fellowship. The MRC Laboratory of Molecular Biology (LMB) is proud to launch a new three-year fully funded postdoctoral fellowship for scientists from Black heritage backgrounds. ... This Fellowship is a three-year

23 Feb 2024: The machines that comprise this proteostasis network include the ribosome, which synthesizes new proteins, chaperones that help new proteins fold, and degradation factors that eliminate incorrect or damaged proteins. ... We expect that our results will

12 Mar 2024: The brain works as an integrated whole. Animals interact with the world by combining inputs from their senses of vision, hearing, smell, taste, touch and

25 Aug 2023: Since the orthogonal ribosome, unlike the natural ribosome, is not essential it is possible to evolve the orthogonal ribosome to read new genetic codes on the orthogonal message. ... This parallel translation pathway provides a series of blank codons

23 Feb 2024: Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and Amyotrophic Lateral Sclerosis (ALS)

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Philipp

21 Jul 2023: Current Vacancies Listed below are the vacancies currently being advertised. In addition we welcome speculative applications from postdocs – see Postdoc

24 Oct 2023: Joan A. Steitz Postdoc Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

23 Feb 2024: Precise chromosome replication is essential for maintaining genome stability, yet the process itself is inherently risky. Duplex DNA must be transiently

21 Jul 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Emeritus.

23 Feb 2024: Information transfer in the nervous system occurs at synapses, where presynaptic signals are interpreted by postsynaptic receptors. We study this process

23 Feb 2024: Cells are highly compartmentalized into numerous membrane-bound organelles. The membranes that define each organelle contain unique sets of embedded

24 Oct 2023: Perutz Student Prize The Perutz Student Prize is awarded annually for outstanding work performed at LMB prior to the award of a Ph.D. Nominees

23 Feb 2024: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Chris Tate

19 Oct 2023: Annette’s aptitude for event organising was again crucial to the Royal Opening of the new LMB building in 2013, when Her late Majesty Queen Elizabeth II and HRH Prince Philip ... A skilled writer herself, Annette also helped publicise research

14 Mar 2024: In an effort to better understand human brain development, we have developed a new model system, called cerebral organoids.

23 Feb 2024: Science News : Scientists have mapped an insect brain in greater detail than ever before. ... Sky News : First map of insect brain signals 'big step forward' in understanding thoughts.

22 Mar 2024: Thus, understanding their cell biology requires re-thinking some of our most basic assumptions (bilayers membranes) and the development of new research tools and methods (high-temperature live cell imaging).

5 Mar 2024: Molecular motors have critical roles in the trafficking of organelles, vesicles and macromolecules within the cytoplasm, and aberrant motor function is

24 Oct 2023: Eileen Southgate Prize The Max Perutz Fund was set up in June 1980 in honour of the LMB’s founder, Max Perutz, and was established for the promotion

21 Jul 2023: Scientific Training Electron Microscopy Biophysics Macromolecular Crystallisation Crystallography Course 2013 Statistics Course 2014 RNA-seq course

23 Feb 2024: The ends of linear eukaryotic chromosomes are capped telomeres, an array of long telomeric repeat tracts (nin human) bound by telomeric protein factors.

13 Feb 2024: Neuronal circuits are the biological substrates for all aspects of brain function such as learning, memory, thought, speech and consciousness. The

23 Feb 2024: Our research is aimed at understanding the mechanisms and regulation of chromosome segregation in mitosis. During the cell cycle, accurate chromosome

21 Jul 2023: In conjunction with Professor Matthew Wood and colleagues at the University of Oxford, we designed a new class of cell-penetrating peptides, called Pip, which showed outstanding cell and in vivo ... The new D-PEP peptides form the basis of founding of a

22 Mar 2024: Molecular Immunity Unit Menna Clatworthy LMB Division - Molecular Immunity Unit The Clatworthy lab is interested in understanding how B cell activation

1 Feb 2024: In 2013, the LMB moved to a new, purpose-built building designed to deliver the right environment in which innovative medical research, translation and collaboration can flourish. ... Both new and established researchers are encouraged to utilise the

23 Feb 2024: We are interested in cell autonomous innate immunity, i.e. in the ability of individual cells to defend themselves against infection. Cytosolic defence

23 Feb 2024: Splicing of precursor messenger RNA (pre-mRNA) is a ubiquitous hallmark of gene expression in all eukaryotes. Within the cell, splicing occurs

14 Mar 2024: Andrew Travers started his Ph.D. at the LMB under the tutelage of the late John Smith in 1964. After this he took a couple of years out as a post-doc in

9 Aug 2023: Technician Commitment The LMB became a signatory of the Technician Commitment in November 2022.  We employ over 150 technical staff in a wide

2 Feb 2024: Cell shape is adapted to function. Organelle shape and local membrane architectures are likewise optimised for the processes that take place on and within

25 Aug 2023: Deorphanisation of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning..

9 Oct 2023: Search this website. New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug targets. ... New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug

27 Jul 2023: Search this website. New insights into how DNA synthesis is started during the process of chromosome replication. ... New insights into how DNA synthesis is started during the process of chromosome replication.

21 Jul 2023: Since retirement in 2010 he has been working part-time in the University of Strathclyde on new types of microscope, using his ‘Mesolens’ and collaborating in published work on nonlinear optics

28 Sep 2023: Search this website. New method to untangle the contribution of signalling pathways involved in asymmetric cell division. ... New method to untangle the contribution of signalling pathways involved in asymmetric cell division.

21 Jul 2023: By using such a tractable model system, we can rapidly discover new pathways and dissect mechanisms that may be directly relevant to a number of human diseases, most notably cystic fibrosis ... We use high throughput yeast genetics to identify new

22 Mar 2024: Collaborations with the University of Cambridge LMB scientists from across the Divisions are also involved in various collaborations and initiatives with

13 Dec 2023: Ordered assembly of a small number of proteins within neurons and, in some cases, glia is a feature of neurodegenerative diseases. These proteins form

12 Sep 2023: In particular, LMB International Fellowships have been created for the development of innovative research, and candidates for these Fellowships would be expected to introduce new scientific projects or expertise into the ... Conversations with colleagues

21 Jul 2023: In collaboration with our pharmaceutical partners, we are seeking to develop HDX-MS approaches to give better insight into conformational dynamics that could result in new therapeutic strategies.

22 Nov 2023: Tobias Wauer shared his experience of volunteering at the UK Biocentre Lighthouse Lab in The Conversation: ‘My new life as a coronavirus tester’. ... The testing volunteers shared details of their experience – see: Putting science skills to new use

21 Jul 2023: In 1969 Brenner and Crick invited him to the LMB to their new Cell Biology division.

25 Aug 2023: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Julian

25 Aug 2023: Despite extracellular immune surveillance, viral and bacterial pathogens are still able to infect cells. This means each cell must have its own mechanisms

21 Jul 2023: A true understanding of biology must include knowledge of its chemical origins, and comprehending the chemical events that gave biology its foundations –

21 Jul 2023: Recently this has focussed on a new graphical user interface (GUI) and developments that will allow more automated data collection and processing, especially at synchrotron beamlines. ... iMosflm: a new graphical interface for diffraction image

21 Jul 2023: years at the University of New South Wales on the structure of carbon fibres.

21 Jul 2023: The Graduate Student Association The LMB has an active Graduate Student Association (GSA), run by and for students, which aims to create an atmosphere of