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2023 John Kendrew Lecture to be given by Wolfgang Baumeister - MRC…
https://www2.mrc-lmb.cam.ac.uk/2023-john-kendrew-lecture-to-be-given-by-wolfgang-baumeister/23 Oct 2023: His research focuses on the development of new tools and methods for the structural characterisation of molecules and cells. -
Nanobody - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/nanobody/21 Jul 2023: Nanobody Mission The Nanobody facility provides a service for the selection and production of nanobodies from either phage display or yeast surface -
Scientific Computing - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/scientific-computing/8 Dec 2023: Scientific Computing Scientific Computing provides and supports the LMB’s core Unix systems. These systems include email, authenticating user access to -
Mass Spectrometry - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/mass-spectrometry-home/21 Jul 2023: The development of new mass spectrometric-based methods is essential in order ensure that the LMB remains at the forefront of biological research. ... The group undertakes independent research to create new mass spectrometric technologies and we -
Tau and Alzheimer's - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-science-stories/tau-and-alzheimers/21 Jul 2023: With recent improvements in electron cryo-microscopy and development of new software that could handle helical samples by Shaoda He in Sjors’ group, they decided to work together to solve the ... Michel: “The most important benefit to emerge from -
Electron Microscopy - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/electron-microscopy/21 Feb 2024: Electron Microscopy The LMB has an outstanding Electron Microscopy (EM) Facility with a focus on electron cryo-microscopy (cryoEM) of unstained biological -
Curios of 60 years of the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/curios-of-60-years-of-the-lmb/21 Jul 2023: Curios of 60 years of the LMB In an exhibition celebrating 60 years of the LMB, an assortment of curios – unusual and intriguing items – have been -
Overview of admissions - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/international-phd-programme/overview-of-admissions/12 Sep 2023: Applicants do not have to make up a new project from thin air! -
Electron Cryo-microscopy - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-science-stories/cryo-electron-microscopy/21 Jul 2023: Electron Cryo-microscopy LMB scientists have been and continue to be at the forefront of the field of electron cryo-microscopy, developing a technique -
1962 - John Kendrew & Max Perutz - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1962-john-kendrew-max-perutz/21 Jul 2023: 1962 Chemistry Prize - John Kendrew & Max Perutz “for their studies of the structures of globular proteins” -
Activation of the integrated stress response by inhibitors of its…
https://www2.mrc-lmb.cam.ac.uk/activation-of-the-integrated-stress-response-by-inhibitors-of-its-kinases/8 Sep 2023: New research from Anne Bertolotti’s group in the LMB’s Neurobiology Division has discovered unexpected dose-dependent activation, rather than the intended inhibition, of ISR by its kinase inhibitors. -
Crystallography Course 2013 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/crystallography-course-2013/21 Jul 2023: Crystallography Course 2013 Lectures Lecture Presentations Tutorials Data Processing and Scaling - Phil Evans and Andrew Leslie Required Software -
Keeping protein subunits in check via assembly quality control - MRC …
https://www2.mrc-lmb.cam.ac.uk/keeping-protein-subunits-in-check-via-assembly-quality-control/21 Jul 2023: Cells eliminate “orphan” proteins that have failed to assemble into the molecular machines within which they normally function. Manu Hegde’s group have now elucidated the mechanism by which one type of orphan is selectively recognised and -
Support Services - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/support-services/21 Jul 2023: Support services IT Support IT Support provides hardware and software configuration and an extensive and speedy repair service for Apple and Windows -
1984 - César Milstein & Georges Köhler - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1984-cesar-milstein-georges-kohler/21 Jul 2023: 1984 Physiology or Medicine Prize - César Milstein & Georges Köhler “for theories concerning the specificity in control and development of the immune -
From the scientist’s view: a conversation with … Manu Hegde - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/manu-hegde-a-conversation/21 Jul 2023: This has occurred because when you come across some new finding, you look around and there are people working on certain topics who you are confident will advise you, tell you ... So some people are amazingly technical, they have this mindset of being -
Cambridge Festival - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-on-the-road/cambridge-science-festival/21 Jul 2023: Cambridge Festival The interdisciplinary Cambridge Festival has replaced the Cambridge Science Festival and Cambridge Festival of Ideas in giving the -
Setting the stage: development of sample holders for electron…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/setting-the-stage-development-of-sample-holders-for-electron-cryomicroscopy-further-information/21 Jul 2023: Setting the stage: development of sample holders for electron cryomicroscopy. The advancement of microscope sample holders was crucial for moving from -
LMB Open Day 2017 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/events-at-the-lmb/lmb-open-day-2017/21 Jul 2023: LMB Open Day 2017 On Saturday 17th June the LMB held a spectacular Open Day as part of the MRC Festival of Medical Research, welcoming over 2000 visitors -
1962 - Francis Crick & James Watson - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/21 Jul 2023: 1962 Physiology or Medicine Prize - Francis Crick & Jim Watson “for their discoveries concerning the molecular structure of nucleic acids and its -
Biological Services Group - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-facilities-and-support-services/biological-services/21 Jul 2023: Biological Services Group The LMB Biological Services Group (BSG) maintains state-of-the-art facilities to house breeding and experimental colonies of -
A database to identify important genes of unknown function for…
https://www2.mrc-lmb.cam.ac.uk/a-database-to-identify-important-genes-of-unknown-function-for-analysis/9 Aug 2023: Despite decades of work, the role of thousands of human proteins remains unclear despite the likelihood that they participate in possibly new areas of biological function. -
Concordat on Openness in Animal Research - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/animal-research/concordat-on-openness-in-animal-research/21 Jul 2023: Concordat on Openness in Animal Research The Concordat on Openness is a declaration signed by many organisations involved with bioscience in the UK. The -
From the scientist’s view: a conversation with … Kelly Nguyen - MRC…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/kelly-nguyen-a-conversation/21 Jul 2023: From the scientist’s view: a conversation with … Kelly Nguyen Kelly Nguyen is a Group Leader in the Structural Studies Division at the LMB. She did her -
2002 - Sydney Brenner, Bob Horvitz & John Sulston - MRC…
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/2002-sydney-brenner-bob-horvitz-john-sulston/21 Jul 2023: In parallel with the generation of new cells, cell death is a normal process, both in the foetus and adult, to maintain the appropriate number of cells in tissues. ... This is now being studied in order to improve the diagnosis of disease, develop new -
Job description and person specification template
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=12061471 Feb 2024: To introduce and apply new techniques across a wide range of disciplines and to have the creativity and initiative to develop novel approaches and methods where required. ... moving into a new research discipline and/or needs to further develop their -
Image Processing Software - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/locally-developed-software/image-processing-software/21 Jul 2023: exe. For developing a new program, the following libraries might need to be invoked:. -
Low energy cryo-EM to widen accessibility for fast and accurate…
https://www2.mrc-lmb.cam.ac.uk/low-energy-cryo-em-to-widen-accessibility-for-fast-and-accurate-structure-determination/28 Nov 2023: This new electron microscope promises to significantly increase the accessibility of cryo-EM. ... A low-cost electron microscope maps proteins at speed, Nature News. Primary Sidebar. -
Raphin 1 and phosphatase inhibitors technology (2018) - MRC…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/raphin1-2018/21 Jul 2023: Overall this new work identifies R15B as a druggable target for Huntington’s disease, and provides the first platform for target-based discovery of inhibitors of serine/threonine phosphatases. ... This novel approach may pave the way to a new -
Trim-Away™ (2017) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/trim-away-2017/21 Jul 2023: Search this website. Trim-Away (2017). Trim-Away is a new technology, developed by Dean Clift, Melina Schuh and Leo James, for the rapid removal of specific proteins from cells through -
Katja Röper: Development of tubular organs - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/katja-roper-development-of-tubular-organs/21 Jul 2023: I would find it very boring and unproductive if I was so competitive that I felt I had to restrict my lab from talking about new data at meetings.”. ... There’s a new group leaders’ group that meets monthly for lunch and presentations, and the -
Repurposed DNA repair factors prevent expansions of ‘parasitic’…
https://www2.mrc-lmb.cam.ac.uk/repurposed-dna-repair-factors-prevent-expansions-of-parasitic-genomic-retrotransposons/14 Aug 2023: New research from Nazareno Bona and Gerry Crossan, in the LMB’s PNAC Division, has identified one of these protections against retrotransposons. ... a new site in the genome. -
Chin
https://www2.mrc-lmb.cam.ac.uk/ccsb/category/publications/feed/3 Apr 2024: W. Chin./p p(124) strongControlling orthogonal ribosome subunit interactions enables evolution of new function. ... James./p p style="padding-left: 60px;"[Featured ina href="http://cen.acs.org/magazine/88/8815.html" target="_blank" rel="noopener -
London International Youth Science Forum - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/supporting-education/london-international-youth-science-forum/21 Jul 2023: The London International Youth Science Forum (LIYSF) is a two-week residential course for students aged 16-21 who have a keen interest in studying -
Royal Society Summer Science Exhibitions - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/lmb-on-the-road/royal-society-summer-science-exhibitions/21 Jul 2023: Royal Society Summer Science Exhibitions Each year the Royal Society holds an annual summer science exhibition that showcases the most exciting -
Past Winners - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/past-events/crystal-growing-competition/past-winners/21 Jul 2023: Winners of the 2013-2014 competition Pupils had five weeks to grow the best-looking crystal of Potash Alum that they could. Their crystals were submitted -
Michel Goedert and Sjors Scheres receive a 2023 Annemarie Opprecht…
https://www2.mrc-lmb.cam.ac.uk/michel-goedert-and-sjors-scheres-receive-a-2023-annemarie-opprecht-parkinson-award/6 Oct 2023: These findings are providing new insights into Parkinson’s disease, which is the most prevalent movement disorder and the second most common neurodegenerative disease, after Alzheimer’s disease. -
Pore-forming protein perforin-2 is critical to immune response by…
https://www2.mrc-lmb.cam.ac.uk/pore-forming-protein-perforin-2-is-critical-to-immune-response-by-dendritic-cells/23 Jun 2023: New research from Patrycja Kozik’s group in the LMB’s PNAC Division has discovered a new pathway of antigen transport from endosomes into the dendritic cytosol. ... This research has helped further understanding of the mechanisms behind T cell -
Patrycja Kozik: From starry nights to immunology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/patrycja-kozik-from-starry-nights-to-immunology/21 Jul 2023: without her family; after school, she then left the country entirely to attend the brand new Jacobs University Bremen as one of its first undergraduates. ... After Bremen, Patrycja moved to Cambridge to do a PhD with Margaret (Scottie) Robinson at the -
I'm a scientist, get me out of here! - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/supporting-education/im-a-scientist-get-me-out-of-here/21 Jul 2023: I'm a Scientist, Get Me Out Of Here is an online public engagement event during which scientists talk with school students from all over the UK and answer -
Structure of γ-Tubulin Ring Complex provides insights into nucleation …
https://www2.mrc-lmb.cam.ac.uk/structure-of-%CE%B3-tubulin-ring-complex-provides-insights-into-nucleation-process-behind-microtubule-formation/15 Apr 2024: An improved knowledge of the process of spindle formation at a molecular level will help to identify new targets for such drugs. -
Centre for Chemical and Synthetic Biology - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/research/protein-and-nucleic-acid-chemistry/centre-for-chemical-and-synthetic-biology/21 Jul 2023: Search this website. Centre for Chemical and Synthetic Biology. Work in the Centre for Chemical and Synthetic Biology (CCSB) aims to develop new approaches to understanding biology at the molecular level, ... both in vitro and in living organisms, and to -
MRC Lab Visits - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/public-engagement/past-events/crystal-growing-competition/mrc-lab-visits/21 Jul 2023: Schools Visits to the LMB Winning schools were invited to bring students to visit the MRC Laboratory of Molecular Biology in Cambridge for a half-day of -
Mesolens Microscopy (2009) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/recent-technology-transfer-initiatives/mesolens-microscopy-2009/21 Jul 2023: As well as being faster, this new type of imaging can reach deeper into solid tissues, such as embryos or tumours. ... The technology has already opened up new possibilities: for macrophotography in biomedical optics, in imaging neurones and mammalian -
Neonatal Mouse Anaesthetisation Mould Request Form - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/research/technology-transfer/neonatal-mouse-anaesthetisation-mould-request-form/21 Jul 2023: Neonatal Mouse Anaesthetisation Mould Request Form Researchers from Dr Ingo Greger’s laboratory at the MRC Laboratory of Molecular Biology have designed a -
1 CURRICULUM VITAE Venki Ramakrishnan Nationality U.S.A. (since 1985) …
https://www2.mrc-lmb.cam.ac.uk/groups/ribo/download/ramakrishnan_cv_brief.pdf4 Jan 2024: The New Science of Aging and the Quest for Immortality 2024: Hodder and Stoughton (UK); William Morrow/HarperCollins (USA) SCIENTIFIC PUBLICATIONS Can be looked up through -
LMB Rising Talent Fellowship Additional Information 1. Is the ...
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=12060822 Feb 2024: This Fellowship is for scientists who have a PhD in a relevant subject (or are due to complete PhD within 6 months), are moving into a new research discipline or have ... Postdoc induction and buddy system for new starters A postdoc buddy is a fellow -
From bench to blockbuster: the story of HUMIRA® – best-selling drug…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/from-bench-to-blockbuster-the-story-of-humira-best-selling-drug-in-the-world/21 Jul 2023: It is now licensed as a treatment for a range of autoimmune diseases and scientists are still discovering new applications. ... Monoclonal antibody technology is behind one third of all new drugs introduced worldwide. -
TDP-43 forms amyloid filaments with distinct folds in different…
https://www2.mrc-lmb.cam.ac.uk/tdp-43-forms-amyloid-filaments-with-distinct-folds-in-different-neurodegenerative-conditions/2 Aug 2023: Published on. 2 August, 2023. Cryo-EM reveals that TDP-43 forms amyloid filaments with a new fold in the most common type of frontotemporal lobar degeneration. ... New research from Benjamin Ryskeldi-Falcon’s group in the LMB’s Neurobiology Division -
LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: A great way to meet new people and relax after a busy day in the lab…. ... sites/nextgen/ that brought scientists from academia and industry together to discuss new developments.
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