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  2. PPL number: | Granted: 04 Apr 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_study_of_epithelial_cancer_genes_nts_expires2022_redacted.pdf
    13 Sep 2021: We will also be studying lung cancer. Nearly 45,000 new cases of lung cancer are diagnosed annually and nearly 35,000 people die from the disease in the UK every ... Our study aims to: 1) Increase the understanding of how types of breast and lung cancers
  3. PPL number: | Granted: 05 Oct 17 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/regulation_of_embryonic_lineages_and_stem_cells_nts_expires2022_redacted.pdf
    13 Sep 2021: However, we sometimes need to breed mice carrying particular genetic modifications to provide early embryos for short-term experiments or to generate new stem cell lines. ... Page 4 of 4. means that we require fewer embryo recipient females for creating
  4. PPL number: | Granted: 28 Oct 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_how_neutrophil_migration_behaviour_is_fine-tuned_during_inflammation_nts_redacted.pdf
    20 Aug 2021: Work from this licence is likely to unravel new ways to manipulate the behaviour of these cells and inflammatory responses therapeutically. ... The key aspect of our programme is to visualise neutrophil behaviours in situ by advanced microscopy techniques
  5. PPL number: | Granted: 03 Jul 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/regeneration_in_the_nervous_system_nts_expires2024_redacted.pdf
    13 Sep 2021: Although stem cells in the brain can make new oligodendrocytes that restore myelin, this regenerative process declines with age. ... Our discoveries may be harnessed to develop new regenerative therapies in the treatment of MS.
  6. PPL number: | Granted: 31 Jan 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/enteroendocrine_signalling_in_health_and_disease_nts_expires2024_redacted.pdf
    13 Sep 2021: What's the aim of this project? After food consumption the gut sends signals to the rest of the body preparing it for the arrival of new nutrients. ... We constantly review the literature whilst planning our experiments and acclimatize animals to new
  7. PPL number: | Granted: 24 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/maternal_and_neonatal_immunity_to_virus_infections_redacted.pdf
    18 Jun 2021: This may be in the form of a new vaccine strategy, or a new anti-viral drug. ... Furthermore, to determine how effective new vaccine approaches are, experimental infections in mice are required.
  8. PPL number: | Granted: 16 Apr 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_of_mental_health_nts_expires2023_redacted.pdf
    13 Sep 2021: Our research aims to understand the bases of these disorders, and develop new treatments for them. ... We also aim to use these models to develop new and better treatments for mental health disorders.
  9. PPL number: | Granted: 06 Aug 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/mice_with_transgenic_immunoglobulin_loci_nts_redacted.pdf
    20 Aug 2021: Given how little innovation there is in veterinary medicine (compared to human medicine), this new class of drugs could have an even bigger impact on pet health than it did on ... In summary: Short-term benefit – New veterinary medicines based on what
  10. PPL number: | Granted: 18 Nov 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/generation_of_novel_antibodies_with_therapeutic_potential_nts_redacted.pdf
    20 Aug 2021: There is a pressing clinical need to identify new types of treatment for human disease (for example, the development of novel antibiotics) and engineered antibodies have considerable potential for this.
  11. PPL number: | Granted: 12 Jul 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_pathogen_behaviour_in_relation_to_the_immunity_vaccines_and_antibiotic_treatment_nts_expires2022_redacted.pdf
    13 Sep 2021: Our research will study how and where the bacteria hide in the body to resist to vaccines and antibiotics and will test new innovative vaccines. ... impact of medical treatments and new vaccines on the behaviour of bacteria in an environment that closely

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