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New analysis approach to identify pathogenesis of Mycobacterium…
https://www2.mrc-lmb.cam.ac.uk/new-analysis-approach-to-identify-pathogenesis-of-mycobacterium-abscessus/25 Aug 2022: abscessus was related to the presence of particular mutations identified by this new ‘phenogenomic’ approach. ... These findings provide proof of concept for the group’s phenogenomic approach to understanding new pathogens. -
Holliger Lab at the LMB
https://www2.mrc-lmb.cam.ac.uk/groups/ph1/xna.html18 Mar 2022: The new synthetic genetic polymers also offer opportunities in biotechnology and promise a new class of biopolymer-based ligands and materials for applications in diagnosis and therapy. -
New method to discover protease and other hydrolase substrates in…
https://www2.mrc-lmb.cam.ac.uk/new-method-to-discover-protease-and-other-hydrolase-substrates-in-live-mammalian-cells/17 Feb 2022: Search this website. New method to discover protease and other hydrolase substrates in live mammalian cells. ... New method to discover protease and other hydrolase substrates in live mammalian cells. -
John Jarvis (1942 – 2022) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/john-jarvis-1942-2022/20 Sep 2022: John Jarvis in the lab, 1960s. When the research John was involved in ended, he applied to work with César, who was now at the LMB, in a new building on ... of the new laboratory building on the Cambridge Biomedical Campus. -
Pathway for making multipass membrane proteins elucidated - MRC…
https://www2.mrc-lmb.cam.ac.uk/pathway-for-making-multipass-membrane-proteins-elucidated/19 Oct 2022: New research from Manu Hegde’s group in the LMB’s Cell Biology Division, in collaboration with Robert Keenan’s lab at the University of Chicago, now sheds light on the ... Their combined efforts not only led to a better understanding of the PAT -
From PhD to elite sports policy research: Aiwei Zeng’s Policy…
https://www2.mrc-lmb.cam.ac.uk/from-phd-to-elite-sports-policy-research-aiwei-zengs-policy-internship/6 Oct 2022: Here, Aiwei discusses her experience, including how work at POST differed to her usual research at the LMB, the new skills she learnt, and why she would recommend other PhD students ... The internship is a really unique opportunity to spend a few months -
Holger Kramer (1979 – 2022) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/holger-kramer-1979-2022/30 Aug 2022: LC-MS and one GC-MS system) and the recruitment of new facility staff to support the expansion. -
Engineered polymerase enzyme presents new opportunity for quick and…
https://www2.mrc-lmb.cam.ac.uk/engineered-polymerase-enzyme-presents-new-opportunity-for-quick-and-efficient-modified-nucleic-acid-synthesis/13 Oct 2022: Search this website. Engineered polymerase enzyme presents new opportunity for quick and efficient modified nucleic acid synthesis. ... Engineered polymerase enzyme presents new opportunity for quick and efficient modified nucleic acid synthesis. -
LMB Through the Years: 60 years of memories - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-through-the-years-60-years-of-memories/15 Dec 2022: He chose to put recruiting lab members on hold, and instead worked by himself for two years, eventually producing RELION, a software package implementing a new and innovative method of image ... recruiting new Group Leaders and the collaborative project -
Sidney Altman 1939 – 2022 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/sidney-altman-1939-2022/12 Apr 2022: Sidney Altman was a ground-breaking scientist in the field of RNA biology, whose discovery of catalytic properties of RNA led to the award of the Nobel -
Andrew McLachlan (1935 – 2022) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/andrew-mclachlan-1935-2022/15 Jul 2022: He was awarded his PhD in 1959. Following this, and with a Harkness Fellowship from the Commonwealth Fund of New York, he was able to work and travel in the United ... In the late 1990s, Andrew developed a new family of mathematical methods and computer -
Donald Caspar 1927 – 2021 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/donald-caspar-1927-2021/7 Jan 2022: Don Caspar, LMB alumnus, has died at the age of 94. Don first came to the MRC Unit for the Study of the Molecular Structure of Biological Systems (now the -
Holliger Lab at the LMB
https://www2.mrc-lmb.cam.ac.uk/groups/ph1/people.html18 Mar 2022: Jennifer L. Ong, PhD. Group leader. New England Biolabs, USA. Marc d’ Abbadie, PhD. -
TMEM106B filaments form in an age-dependent manner in human brains -…
https://www2.mrc-lmb.cam.ac.uk/tmem106b-filaments-form-in-an-age-dependent-manner-in-human-brains/28 Mar 2022: Building upon previous collaborative studies of these proteins, Sjors Scheres and Michel Goedert’s groups have now identified TMEM106B as a new protein which forms amyloid filaments in human brains. -
The beauty of brain organoids - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/the-beauty-of-brain-organoids/2 Nov 2022: Madeline Lancaster, a Group Leader in the LMB’s Cell Biology Division, discusses her career and the opportunities brain organoids provide as a tool for -
Carolyn Bertozzi to deliver 2022 Max Perutz Lecture - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/carolyn-bertozzi-to-deliver-2022-max-perutz-lecture/21 Mar 2022: Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies. ... Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities -
Ben Porebski’s path to the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/ben-porebskis-path-to-the-lmb/3 Aug 2022: Ben Porebski, an Investigator Scientist in Philipp Holliger’s group in the LMB’s PNAC Division, discusses his career so far, including how Australia’s -
The journey to solving structures - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/the-journey-to-solving-structures/3 Mar 2022: Richard Henderson, from the LMB’s Structural Studies Division, discusses his work and the evolution of structural biology on the Knowable podcast. More... -
Curios of 60 years of the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/curios-of-60-years-of-the-lmb/30 Mar 2022: Celebrating 60 years of the LMB, an exhibition of unusual and intriguing items gives a glimpse into the life and work of the LMB -
In-person public engagement returns after lockdown - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/in-person-public-engagement-returns-after-lockdown/13 Apr 2022: Earlier in March during British Science Week, some of our scientists brought both existing and brand-new activities into primary schools. ... Anna had the following reflections on the new challenges faced by scientists as they take part in public -
Jason Chin elected Fellow of Royal Society - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/jason-chin-elected-fellow-of-royal-society/10 May 2022: Each year the Fellows of the Royal Society elect up to 52 new Fellows, and up to 10 new Foreign Members. ... He has rewritten the near-universal genetic code of natural life to create organisms that use new genetic codes. -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/structures.html7 Mar 2022: Our structures. Our methods aim to open up new experimental possibilities in Structural Biology studies. ... By ourselves or through collaborations, we have used our methods to determine new structures. -
EMBO announces 2023 elections for Young Investigator Programme - MRC…
https://www2.mrc-lmb.cam.ac.uk/embo-announces-2023-elections-for-young-investigator-programme/22 Nov 2022: EMBO welcomes the new Young Investigators with a sense of excitement and pride. -
New research initiative at the University of Cambridge supports a…
https://www2.mrc-lmb.cam.ac.uk/new-research-initiative-at-the-university-of-cambridge-supports-a-cross-disciplinary-approach-to-better-understand-life-across-the-universe/19 Jan 2022: Search this website. New research initiative at the University of Cambridge supports a cross-disciplinary approach to better understand life across the Universe. ... New research initiative at the University of Cambridge supports a cross-disciplinary -
Aaron Klug: A Scientific Retrospective - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/aaron-klug-a-scientific-retrospective/7 Jun 2022: Steve Harrison highlighted how Aaron was continually moving on to different areas of research: “each of the things he [Aaron] moved on to, created both a new field – a platform for -
LMB becomes signatory of the Technician Commitment - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/lmb-becomes-signatory-of-the-technician-commitment/16 Nov 2022: The LMB is proud to announce that we have joined the Technician Commitment as a signatory. The commitment aims to ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across -
Fred Sanger (1918 - 2013) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/fred-sanger/6 Oct 2022: Structure of Biological Systems, lead by Max Perutz, to join them in plans for a new laboratory. -
Reaching further with our 2023 Microscopes4Schools Competition - MRC…
https://www2.mrc-lmb.cam.ac.uk/reaching-further-with-our-2023-microscopes4schools-competition/9 Nov 2022: After running previously as the Science Image Award, the newly named Microscopes4Schools Competition will continue to offer online ‘Meet the Researcher’ sessions with schools as we expand our reach beyond Cambridge and broaden our judging panel -
How alpacas help solve protein structures - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-alpacas-help-solve-protein-structures/28 Oct 2022: The LMB is the proud owner of four alpacas, which we have recently inoculated to induce nanobody production to study complex protein structures -
The age-old problem of telomere maintenance - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/the-age-old-problem-of-telomere-maintenance/24 Nov 2022: Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division, was awarded the 2022 Eppendorf Award for Young European Investigators earlier this -
Suzanne Cory and Joan Steitz in conversation - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/suzanne-cory-and-joan-steitz-in-conversation/13 Oct 2022: Suzanne Cory and Joan Steitz talk to Joan Heath about their memories of LMB in the 1960s, their careers since, and their thoughts on past and present -
Vernon Ingram. 19 May 1924 - 17 August 2006 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/vernon-ingram-19-may-1924-17-august-2006/23 Aug 2022: Vernon Ingram, born in Germany, was a protein chemist who helped advance the field of protein crystallography and made important contributions to the -
Venki Ramakrishnan appointed to the Order of Merit - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-appointed-to-the-order-of-merit/14 Nov 2022: Bacterial ribosomes are different from those in higher organisms, making them good targets for drugs, so this information is critical in developing new antibiotics to combat infection and disease. -
Kathleen Weston - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/kathleen-weston/2 Nov 2022: Dr Kathleen Weston Kathleen Weston was a PhD student with Bart Barrell at the MRC Laboratory of Molecular Biology from 1983 to 1986. After postdoctoral -
Nina Rzechorzek on daily brain temperature rhythms - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/nina-rzechorzek-on-daily-brain-temperature-rhythms/16 Dec 2022: Nina Rzechorzek, a member of the O’Neill group in the LMB’s Cell Biology Division, was lead author on a paper in Brain earlier this year. This podcast -
Annual LMB student, postdoc and staff prizes awarded - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/annual-lmb-student-postdoc-and-staff-prizes-awarded/24 Oct 2022: He leveraged his engineered enzymes to yield exciting new aptamers with unique ligands. ... This work holds tremendous potential for therapeutic benefit through in vitro evolution of new catalysts and aptamers. -
Kiyoshi Nagai. 25 June 1949 – 27 September 2019 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/kiyoshi-nagai-25-june-1949-27-september-2019/23 Mar 2022: Kiyoshi Nagai was a preeminent researcher at the LMB for over thirty years during which he was a global leader in the field of spliceosome research. His -
In person return for Next Generation Biophysics Symposium - MRC…
https://www2.mrc-lmb.cam.ac.uk/in-person-return-for-next-generation-biophysics-symposium/26 Oct 2022: As with previous symposia, researchers from both academic and industry backgrounds were welcomed for stimulating talks and discussions on how new and emerging technologies could be applied to address challenging questions -
Lister Institute Prize Lectures delivered at LMB - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lister-institute-prize-lectures-delivered-at-lmb/29 Jun 2022: new therapeutic strategies. ... an individual, defining the process by which new variants likely arise, and also reporting some of the first data on Pfizer BioNTech vaccine-induced antibody responses against the -
Stephen McLaughlin appointed Head of Biophysics Facility - MRC…
https://www2.mrc-lmb.cam.ac.uk/stephen-mclaughlin-appointed-head-of-biophysics-facility/18 Nov 2022: able to answer questions in new and innovative ways”. -
Morten Meldal shares 2022 Nobel Prize in Chemistry - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/morten-meldal-shares-2022-nobel-prize-in-chemistry/5 Oct 2022: Morten Meldal shares the 2022 Nobel Prize in Chemistry with Carolyn R. Bertozzi and K. Barry Sharpless for “the development of click chemistry and -
Terry Rabbitts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/terry-rabbitts/19 Apr 2022: Since moving from LMB to Leeds and Oxford then ICR, he has worked on new technologies for cancer therapy using antibody fragments inside cells and developed novel methods using intracellular antibodies ... He was also part of the the early planning of -
LMB raises over £1500 for Addenbrooke’s Charitable Trust - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-over-1500-for-addenbrookes-charitable-trust/17 Jan 2022: The annual LMB charity Christmas raffle, and Craft and Chatter Group sale, has raised £1545.00 for the Addenbrooke’s Charitable Trust (ACT). -
Pathway behind pathogenic mechanism of tuberculosis identified - MRC…
https://www2.mrc-lmb.cam.ac.uk/pathway-behind-pathogenic-mechanism-of-tuberculosis-identified/24 Jun 2022: This new study from Lalita’s group highlights the RET pathway’s role as a major pathogenic mechanism of TB too. -
Lalita Ramakrishnan joins the LMB Cell Biology Division - MRC…
https://www2.mrc-lmb.cam.ac.uk/lalita-ramakrishnan-joins-the-lmb-cell-biology-division/2 Feb 2022: I also hope to lure my new colleagues into using the zebrafish by showing them it’s awesome power.” – Lalita. -
2022 John Kendrew Lecture to be given by Alice Ting - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/2022-john-kendrew-lecture-to-be-given-by-alice-ting/5 May 2022: Her group is dedicated to the development of new technologies to map molecules, cells and functional circuits and applying these to better understand signalling in mitochondria and in the mammalian brain. ... Utilising both chemical and biological methods -
Cambridge demonstrates how science is improving lives - MRC…
https://www2.mrc-lmb.cam.ac.uk/cambridge-demonstrates-how-science-is-improving-lives/25 Jan 2022: The LMB recently welcomed George Freeman MP as part of a wider visit to the Cambridge Biomedical Campus to learn how Cambridge is leading innovation in -
Madeline Lancaster recognised in the 2022 Blavatnik Awards - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-recognised-in-the-2022-blavatnik-awards/19 Jan 2022: The Blavatnik Awards are supported by the Blavatnik Family Foundation and independently administered by the New York Academy of Sciences. -
Functional human replisome reconstituted for the first time - MRC…
https://www2.mrc-lmb.cam.ac.uk/functional-human-replisome-reconstituted-for-the-first-time/18 May 2022: The new system has revealed a number of important insights into fundamental aspects of human DNA replication. ... Thus, this new system allows for novel insights specific to the human replisome. -
Kenneth Holmes (1934 – 2021) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/kenneth-holmes-1934-2021/28 Jan 2022: He developed new methods of measuring, scaling and processing X-ray data and along with Bill Longley developed a fine focus rotating anode tube which significantly reduced the number of hours ... This led to the development of a new type of camera which
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