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Fred Sanger at the LMB - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-news/fred-sanger-at-the-lmb-2/6 Oct 2022: After more than 10 years, the dideoxy sequencing technique, a brand new approach to sequencing, was developed. ... It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge. -
Thomas Arthur Steitz. 23 August 1940 – 9 October 2018 - MRC…
https://www2.mrc-lmb.cam.ac.uk/thomas-arthur-steitz-23-august-1940-9-october-2018/17 Jan 2022: Thomas Steitz was among the foremost of the generation that was responsible for an explosion in our understanding of the structure and function of -
Inter-institute Technician Symposium celebrates technical specialists …
https://www2.mrc-lmb.cam.ac.uk/inter-institute-technician-symposium-celebrates-technical-specialists/25 Oct 2022: Technical staff from three institutes were invited to the event to network and share inspiring career stories. -
Constructive Bio launched to build on synthetic biology breakthroughs …
https://www2.mrc-lmb.cam.ac.uk/constructive-bio-launched-to-build-on-synthetic-biology-breakthroughs/19 Aug 2022: 19 August, 2022. New UK-based biotechnology company launched to scale and commercialise ground-breaking synthetic biology research of Jason Chin. ... Jason commented, “Over the last 20 years, we have created a cellular factory that we can reliably and -
2022 Francis Crick Lecture to be given by Catherine Dulac - MRC…
https://www2.mrc-lmb.cam.ac.uk/2022-francis-crick-lecture-to-be-given-by-catherine-dulac/27 Oct 2022: In this lecture, I will describe our recent progress in understanding how the brain participates in the positive and negative control of adult-adult social interactions, providing a new framework to -
Redefining human brain temperature and its clinical utility - MRC…
https://www2.mrc-lmb.cam.ac.uk/redefining-human-brain-temperature-and-its-clinical-utility/27 Jun 2022: Magnetic resonance spectroscopy allowed Nina Rzechorzek (member of the O’Neill group, Cell Biology) and collaborators to create a HEATWAVE map, showing -
The LMB Arts and Crafts Show displays a variety of talent - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-arts-and-crafts-show-displays-a-variety-of-talent/8 Aug 2022: It was also a fantastic way to meet new people.”. Also highlighted was a selection of wood-turned items from Geoff Wilkinson, Head of Domestic Services. ... It’s always a delight to see the work of new and regular exhibitors. -
Ruth Lehmann receives Vanderbilt Prize in Biomedical Science - MRC…
https://www2.mrc-lmb.cam.ac.uk/ruth-lehmann-receives-vanderbilt-prize-in-biomedical-science/29 Apr 2022: Ruth Lehmann is the 2022 recipient of the Vanderbilt Prize in Biomedical Science, given to women with outstanding research accomplishments and established -
LMB extends Blue Sky research collaboration with AstraZeneca - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-extends-blue-sky-research-collaboration-with-astrazeneca/30 May 2022: The LMB has agreed to an additional $4 million to be used to facilitate further research partnerships with AstraZeneca, as part of the joint Blue Sky collaboration -
Tanmay Bharat wins the 2023 Microbiology Society Fleming Prize - MRC…
https://www2.mrc-lmb.cam.ac.uk/tanmay-bharat-wins-the-2023-microbiology-society-fleming-prize/22 Nov 2022: Tanmay Bharat is awarded the 2023 Microbiology Society Fleming Prize. His research uses electron tomography to study prokaryotic cell surfaces, playing important roles in prokaryotic physiology, as well in human bacterial infections. -
Refactoring the genetic code to create organisms protected by a…
https://www2.mrc-lmb.cam.ac.uk/refactoring-the-genetic-code-to-create-organisms-protected-by-a-genetic-firewall/24 Oct 2022: This provides a new paradigm which both protects valuable engineered organisms from natural invaders and safeguards the natural world from engineered genetic material. ... Jerome demonstrated that genes which use the new synthetic code could only be -
Paul Sigler (1934 - 2000) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/paul-sigler-1934-2000/2 Nov 2022: Paul Sigler (1934 - 2000) Paul Sigler came to the MRC Laboratory of Molecular Biology in 1964 as a Helen Hay Whitney fellow to work with Brian Matthews -
Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/donald-caspar-1927-2021/5 Jan 2022: In 2014, he attended the LMB Alumni Symposium: Molecular Biology at 50 and Beyond, in the recently opened new LMB building, and recounted his time at the LMB in a -
Madeline Lancaster and Menna Clatworthy elected to EMBO membership -…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-and-menna-clatworthy-elected-to-embo-membership/6 Jul 2022: New members are elected annually, by the existing membership, in recognition of their contribution to scientific excellence. ... 19. Menna responded to the news, “I am delighted to be recognised by EMBO. -
Identification of pathway that enables resistance to tuberculosis -…
https://www2.mrc-lmb.cam.ac.uk/identification-of-pathway-that-enables-resistance-to-tuberculosis/29 Sep 2022: It is from these necrotic granulomas that the bacteria can transmit best to new individuals thereby maintaining the global burden of TB. ... A new study from Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and Head of the Molecular -
Sidney Altman 1939 – 2022 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-sidney-altman/12 Apr 2022: He died in Rockleigh, New Jersey, aged 82, on 5 April 2022, after a long illness. -
The making of ‘Inside the LMB: One-take fly through’ - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/the-making-of-inside-the-lmb-one-take-fly-through/12 Oct 2022: Take a look behind the scenes of the LMB’s single-shot drone film, Inside the LMB: One take fly through. -
Wasi Faruqi reminisces on his scientific career in Cambridge - MRC…
https://www2.mrc-lmb.cam.ac.uk/wasi-faruqi-reminisces-on-his-scientific-career-in-cambridge/13 Jan 2022: Wasi Faruqi joined the LMB in 1969 where he has since remained as an integral contributor to the lab’s Structural Studies Division. In 2021 Wasi’s work on -
Proteins required for processing the end of mRNAs identified - MRC…
https://www2.mrc-lmb.cam.ac.uk/proteins-required-for-processing-the-end-of-mrnas-identified/17 May 2022: Two new papers from Lori Passmore’s group in the LMB’s Structural Studies Division seek to provide some clarity on this issue. -
Tripodi Lab
https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/feed/3 May 2022: But what if I add an extra “L” and an extra “R”; how do I parse this new action-emphrase /emthen? ... Clearly the last two points are far from being proven and new experiments could be designed, starting from the current experimental design, in -
From the LMB to Silicon Valley: Inja Radman discusses her career -…
https://www2.mrc-lmb.cam.ac.uk/from-the-lmb-to-silicon-valley-inja-radman-discusses-her-career/11 Aug 2022: Inja Radman discusses her career so far with Women Ahead of Their Time (WATT), including the “fantastic time” she spent as a PhD student and Investigator -
160 not out: Celebrating those with 4 decades of LMB service - MRC…
https://www2.mrc-lmb.cam.ac.uk/160-not-out-celebrating-those-with-4-decades-of-lmb-service/26 Apr 2022: Over the last 40 years, Paul has spearheaded several huge and vital projects; from designing the IT system for the new LMB building and facilitating the mass shift to work from ... Pat is also an active member of the LMB Green Committee, who are -
Michael Webster joins the John Innes Centre as a Group Leader - MRC…
https://www2.mrc-lmb.cam.ac.uk/michael-webster-joins-the-john-innes-centre-as-a-group-leader/10 Jan 2022: Michael Webster shares insights into his research, scientific interests and career so far as he joins the John Innes Centre as a Group Leader. Michael -
Nikolai Kiselev (1928 – 2016) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/nikolai-kiselev-1928-2016/23 Mar 2022: Nikolai Kiselev (1928 – 2016) Nikolai Kiselev was a long-term supporter and collaborator of the LMB. He first visited the Lab in 1966, as a Postdoctoral -
Anne Bertolotti appointed as Joint Head of the LMB's Neurobiology …
https://www2.mrc-lmb.cam.ac.uk/anne-bertolotti-appointed-as-joint-head-of-the-lmbs-neurobiology-division/14 Oct 2022: The Division has been expanding significantly over the last 10 years, as new areas of research have been added, in addition to other successful areas being extended. ... In April 2017, she was awarded the GlaxoSmithKline Award for recognition of research -
Michel Goedert discusses his life and career in research with DZNE -…
https://www2.mrc-lmb.cam.ac.uk/michel-goedert-discusses-his-life-and-career-in-research-with-dzne/16 May 2022: To mark the award of the Hartwig Piepenbrock-DZNE Prize for his ground-breaking research into the molecular basis of neurodegenerative diseases, DZNE have -
A virus-resistant organism - and what it could mean for the future -…
https://www2.mrc-lmb.cam.ac.uk/a-virus-resistant-organism-and-what-it-could-mean-for-the-future/31 Oct 2022: Jason Chin, Joint Head of the PNAC Division, presents a TedTalk on his groundbreaking work in synthetic biology. Jason explores what would happen if we -
Cryo-EM structures reveal molecular basis of human telomerase…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-structures-reveal-molecular-basis-of-human-telomerase-recruitment/25 Feb 2022: A new study from Kelly Nguyen’s group in the LMB’s Structural Studies Division has provided structures, which reveal unprecedented insights into the molecular basis underlying how shelterin recruits telomerase, -
Anthony Hyman is joint winner of 2023 Breakthrough Prize for Life…
https://www2.mrc-lmb.cam.ac.uk/anthony-hyman-is-joint-winner-of-2023-breakthrough-prize-for-life-sciences/23 Sep 2022: Anthony, along with Clifford Brangwynne, discovered an entirely new mechanism for cellular organisation that concentrates cellular interactions between proteins and other biomolecules in membraneless droplets. -
LMB students recognised by Cambridge Society for the Application of…
https://www2.mrc-lmb.cam.ac.uk/lmb-students-recognised-by-cambridge-society-for-the-application-of-research/10 Jun 2022: Last year, Katerina published a new method to produce specimen support grids for electron cryo-microscopy (cryo-EM). ... The new grids, made of gold, provide superior quality data and can be manufactured in a scalable way which could ease the bottleneck -
Sjors Scheres is elected Fellow of the Academy of Medical Sciences -…
https://www2.mrc-lmb.cam.ac.uk/sjors-scheres-is-elected-fellow-of-the-academy-of-medical-sciences/11 May 2022: Sjors Scheres, Group Leader and Joint Head of the Structural Studies Division, has been elected into the Fellowship of the Academy of Medical Sciences. -
César Milstein Lecture to be given by Uğur Şahin and Özlem Türeci -…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-ugur-sahin-and-ozlem-tureci/19 Jul 2022: BioNTech co-founders Uğur Şahin and Özlem Türeci will discuss using mRNA technology in vaccines to treat cancer and COVID-19. -
Structural study reveals unexpected diversity in GABAA receptor…
https://www2.mrc-lmb.cam.ac.uk/structural-study-reveals-unexpected-diversity-in-gabaa-receptor-assembly/30 Mar 2022: The findings from this study present a new way of looking at the field of molecular neuroscience in general. -
Human inner kinetochore structure reveals mechanism for binding DNA…
https://www2.mrc-lmb.cam.ac.uk/human-inner-kinetochore-structure-reveals-mechanism-for-binding-dna-during-mitosis/19 Apr 2022: A new study from David Barford’s group in the LMB’s Structural Studies Division, has solved the structure of the human inner kinetochore when bound to a CENP-A nucleosome, ... These new insights into how the kinetochore functions could prove -
Structural study reveals a novel activation mechanism for the fungal…
https://www2.mrc-lmb.cam.ac.uk/structural-study-reveals-a-novel-activation-mechanism-for-the-fungal-gpcr-ste2/16 Mar 2022: Now, new research from the group has shown that Ste2 has a novel method of activation which is unique from mammalian GPCRs. ... Computational processing of the datasets led to the determination of four new Ste2 structures; a ligand-free state, an -
Kelly Nguyen has won the 2022 Eppendorf Award for Young European…
https://www2.mrc-lmb.cam.ac.uk/kelly-nguyen-has-won-the-2022-eppendorf-award-for-young-european-investigators/6 Jul 2022: Structural Studies Group Leader Kelly Nguyen has been honoured by the 2022 Eppendorf Award for Young European Investigators for her innovative research on the spliceosome and telomeres. -
From the LMB to food supplement development: Miriam Ferrer discusses…
https://www2.mrc-lmb.cam.ac.uk/from-the-lmb-to-food-supplement-development-miriam-ferrer-discusses-her-career/28 Sep 2022: For Food Matters Live, Miriam Ferrer discusses her career to date, including her time at the LMB and how her passion for science was ignited by a -
Structural analysis of GABAA receptors reveals unexpected diversity…
https://www2.mrc-lmb.cam.ac.uk/structural-analysis-of-gabaa-receptors-reveals-unexpected-diversity-of-arrangements/8 Apr 2022: The Cambridge Independent reports on a recent paper from Radu Aricescu’s group in the LMB’s Neurobiology Division. His group’s structural investigation -
Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic…
https://www2.mrc-lmb.cam.ac.uk/mammalian-clock-gene-cryptochrome-1-is-crucial-to-suprachiasmatic-nucleus-timekeeping/31 Aug 2022: Acute changes in the amount of CRY1 was able to reset the clocks of independent SCN to a new, common phase. -
Brad Amos on microscopy design, writing LMB Christmas skits, and…
https://www2.mrc-lmb.cam.ac.uk/brad-amos-on-microscopy-design-writing-lmb-christmas-skits-and-diving-with-sharks/11 Mar 2022: Emeritus scientist Brad Amos is a guest on The Microscopists podcast from Bitesize Bio. Listen to him chat to host Peter O’Toole about his career, -
Cryptochrome proteins are integral to maintain time within the…
https://www2.mrc-lmb.cam.ac.uk/cryptochrome-proteins-are-integral-to-maintain-time-within-the-brains-master-clock/20 Jan 2022: mechanisms. A new study from Michael Hastings’ group in the LMB’s Neurobiology Division, in collaboration with Andrew Loudon at the University of Manchester, utilised advanced synthetic biological methodology, pioneered by -
DNA replication initiation shapes the evolution and expression of the …
https://www2.mrc-lmb.cam.ac.uk/dna-replication-initiation-shapes-the-evolution-and-expression-of-the-human-genome/10 Nov 2022: The presence of breaks at origins was confirmed using a new technique called INDUCE-seq, which allows the very precise mapping of DNA break (developed by Simon Reed’s group, University -
Looking Back: Facundo D. Batista - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/looking-back-facundo-d-batista/14 Dec 2022: I have had the opportunity to oversee the design of a new building for the Ragon Institute, which will be completed in 2024. -
The Royal Society awards the Francis Crick Medal and Lecture 2023 to…
https://www2.mrc-lmb.cam.ac.uk/the-royal-society-awards-the-francis-crick-medal-and-lecture-2023-to-tiago-branco/26 Aug 2022: Tiago Branco is the 2023 recipient of The Royal Society’s Francis Crick Medal and Lecture in recognition of his research into molecular, cellular and -
In The Stem Cell Jungle explore how embryonic stem cell signalling…
https://www2.mrc-lmb.cam.ac.uk/in-the-stem-cell-jungle-explore-how-embryonic-stem-cell-signalling-drives-cell-fate/18 Jan 2022: Marta Shahbazi discusses her lab’s work on the benefits of culturing embryonic stem cells in 3D to better understand how stem cell signalling drives cell -
Cryo-EM reveals first high-resolution structure of the…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-reveals-first-high-resolution-structure-of-the-dynein-dynactin-complex-bound-to-microtubules/7 Sep 2022: Published on. 7 September, 2022. New structure reveals how dynein motor domains interact and how a pair of cargo adaptors use conserved sequence motifs to scaffold the motor protein complex. -
Stephen Wallace is the 2023 recipient of The Colworth Medal from The…
https://www2.mrc-lmb.cam.ac.uk/stephen-wallace-is-the-2023-recipient-of-the-colworth-medal-from-the-biochemical-society/7 Apr 2022: Stephen Wallace has been awarded The Colworth Medal, given by The Biochemical Society to recognise outstanding research by a biochemist within 10 years of -
Andrew Beale announced a Public Outreach Fellow for the Society for…
https://www2.mrc-lmb.cam.ac.uk/andrew-beale-announced-a-public-outreach-fellow-for-the-society-for-research-on-biological-rhythms/6 Jul 2022: Published on. 6 July, 2022. Andrew Beale, a postdoc in John O’Neill’s group in the LMB’s Cell Biology Division, discusses his plans as new Public Outreach Fellow for -
Final_2022 M4S Competition review infographic
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=27454&ind=166695472302824 Oct 2022: setting. 11 of the 18 schools were new from across Cambridgeshire, Bedford and Peterborough. ... pandemic. 61% new schools. Highfield Littleport Academy,. Cambridgeshire(Special School). first time of using a microscope in science. -
Identical structures of α-synuclein filaments from Parkinson’s…
https://www2.mrc-lmb.cam.ac.uk/identical-structures-of-%CE%B1-synuclein-filaments-from-parkinsons-disease-and-dementia-with-lewy-bodies/20 Sep 2022: This new study establishes the existence of multiple molecular conformers of synucleinopathies. ... The new work also opens the way to the development of methods by which to produce α-synuclein filaments with structures identical to those in human brains
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