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  2. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure.
  3. BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf
    29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in
  4. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  5. Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/
    Thumbnail for Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology 30 Mar 2021: the centre of the new field of molecular biology.
  6. Mark Bretscher - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mark-bretscher/
    Thumbnail for Mark Bretscher - MRC Laboratory of Molecular Biology 30 Mar 2021: Mark S. Bretscher Mark Bretscher studied Chemistry at the University of Cambridge, before joining the MRC Laboratory of Molecular biology as a research
  7. Heart cell clocks help coordinate daily cardiac function - MRC…

    https://www2.mrc-lmb.cam.ac.uk/heart-cell-clocks-help-coordinate-daily-cardiac-function/
    Thumbnail for Heart cell clocks help coordinate daily cardiac function - MRC Laboratory of Molecular Biology 21 Oct 2021: Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through
  8. Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC…

    https://www2.mrc-lmb.cam.ac.uk/francis-crick-lecture-to-be-given-by-michel-c-nussenzweig/
    Thumbnail for Francis Crick Lecture to be given by Michel C. Nussenzweig - MRC Laboratory of Molecular Biology 8 Nov 2021: Michel received a B.C. summa cum laude from New York University in 1976, a PhD degree with Ralph Steinman from Rockefeller University in 1981 and an M.D. ... degree from New York University Medical School in 1982. Following this he completed a medical
  9. Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC…

    https://www2.mrc-lmb.cam.ac.uk/michel-goedert-awarded-the-2021-hartwig-piepenbrock-dzne-prize/
    Thumbnail for Michel Goedert awarded the 2021 Hartwig Piepenbrock-DZNE Prize - MRC Laboratory of Molecular Biology 15 Oct 2021: Hopefully, the new knowledge will lead to the development of safe and effective mechanism-based therapies for common neurodegenerative diseases.”.
  10. Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/wasi-faruqi-awarded-mbe-in-queens-birthday-honours/
    Thumbnail for Wasi Faruqi awarded MBE in Queen’s Birthday Honours - MRC Laboratory of Molecular Biology 14 Jun 2021: Wasi (Abdul Raffey) Faruqi, from the LMB’s Structural Studies Division, has been made a MBE in the Queen’s 2021 Birthday Honours List
  11. John Finch Collection - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/john-finch-collection/
    Thumbnail for John Finch Collection - MRC Laboratory of Molecular Biology 31 Mar 2021: He came to the new LMB in 1962 with the Birkbeck group, which was now led by Aaron Klug after Rosalind’s death in 1958.
  12. Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/max-perutz-1914-2002/
    Thumbnail for Max Perutz (1914 - 2002) - MRC Laboratory of Molecular Biology 30 Mar 2021: This move would lead to him becoming a pioneer in the new field of molecular biology, co-founding a world-class research laboratory and developing a technique to unlock the structures
  13. César Milstein Lecture to be given by Hans Clevers - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-hans-clevers/
    Thumbnail for César Milstein Lecture to be given by Hans Clevers - MRC Laboratory of Molecular Biology 23 Nov 2021: Hans Clevers from the Hubrecht Institute will deliver the 2021 César Milstein Lecture on how organoids can be used to model human diseases.
  14. Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/COVID%20vaccine%202021%201873-3468.14171.pdf
    29 Aug 2021: Q5 High-Fidelity 2X Master Mix (New England Biolabs,. Ipswich, MA, USA) as per manufacturer’s instructions.
  15. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  16. A colourful welcome back for the LMB Arts and Crafts Show - MRC…

    https://www2.mrc-lmb.cam.ac.uk/a-colourful-welcome-back-for-the-lmb-arts-and-crafts-show/
    Thumbnail for A colourful welcome back for the LMB Arts and Crafts Show - MRC Laboratory of Molecular Biology 5 Aug 2021: The LMB Arts and Crafts Show: showcasing the creative talents of the LMB
  17. Madeline Lancaster on serendipity and adventure in science - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-on-serendipity-and-adventure-in-science/
    Thumbnail for Madeline Lancaster on serendipity and adventure in science - MRC Laboratory of Molecular Biology 22 Sep 2021: Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids –
  18. Dr. George Pieczenik - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/dr-george-pieczenik/
    Thumbnail for Dr. George Pieczenik - MRC Laboratory of Molecular Biology 30 Mar 2021: Dr. George Pieczenik Dr. George Pieczenik worked in the MRC Laboratory of Molecular Biology at intervals during the years 1972-1987. He was an early
  19. Bretscher Archive - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/manuscripts-correspondence/bretscher-archive/
    Thumbnail for Bretscher Archive - MRC Laboratory of Molecular Biology 28 Sep 2021: Search this website. Bretscher Archive. The MRC Unit moved out of the Cavendish Laboratory to the new LMB site in early 1962.
  20. Publications

    https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html
    14 Apr 2021: Henderson, R. IUCrJ 3, 3-7 (2016). CryoEM at IUCrJ: a new era. ... Caspar, D.L.D. Nature, News & Views 345, 666-667 (1990). Bacteriorhodopsin - at last!
  21. 16262551036386 1..32

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cohesin%20folding%202021%20elife-67268-v1.pdf
    14 Jul 2021: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 28. Received:
  22. A unified evolutionary origin for the ubiquitous protein transporters …

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/BMC_Biology_2021.pdf
    15 Dec 2021: s hydrophilic groove and its capping hydrophobicresidue are homologous to key residues in SecY’s hydro-philic funnels and its pore ring, respectively.In light of this new correspondence, we
  23. The mechanisms of integral membrane protein biogenesis

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/NRMCB_2021.pdf
    22 Sep 2021: These areas have recently seen the discovery of new machinery, mechanis-tic insights from structural and bioinformatics analysis, and the emergence of new concepts. ... Here we consider comparatively recent new insights into the basis of SRP substrate
  24. Science Journals — AAAS

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf
    26 Aug 2021: The PSMC5 construct for in vitro translation in the PURE system was similar to that in pSP64, but in the T7-based PURExpress plasmid from New England Biolabs. ... The resin was then. 6. washed 5 times in PSB, and transferred to a new tube.
  25. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  26. Madeline Lancaster awarded the 2021 ISSCR Dr Susan Lim Award - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-awarded-the-2021-isscr-dr-susan-lim-award/
    Thumbnail for Madeline Lancaster awarded the 2021 ISSCR Dr Susan Lim Award - MRC Laboratory of Molecular Biology 26 Jan 2021: They found that ChP cells express ACE2, the receptor needed for SARS-CoV-2 entry, on their surface and that the virus was able to infect and produce new virus inside ... The development of cerebral organoids has significant implications not only for
  27. Hans Boye - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-hans-boye/
    Thumbnail for Hans Boye - MRC Laboratory of Molecular Biology 30 Mar 2021: Hans Boye Hans Boye was a research student with Francis Crick from October 1961-1964, and was Crick's second and last student. His area of research was on
  28. Bernard Jacrot - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/bernard-jacrot/
    Thumbnail for Bernard Jacrot - MRC Laboratory of Molecular Biology 30 Mar 2021: With Maier-Leibnitz, they recruited the young German and French scientists and engineers who designed and built a new generation of instruments (some of which were politely considered to be ‘odd’ ... He established a group in structural virology that
  29. Chris Tate and Sjors Scheres elected Fellows of Royal Society - MRC…

    https://www2.mrc-lmb.cam.ac.uk/chris-tate-and-sjors-scheres-elected-fellows-of-royal-society/
    Thumbnail for Chris Tate and Sjors Scheres elected Fellows of Royal Society - MRC Laboratory of Molecular Biology 6 May 2021: Each year the Fellows of the Royal Society elect up to 52 new Fellows, and up to 10 new Foreign Members. ... Our new Fellows and Foreign Members are all at the forefronts of their fields from molecular genetics and cancer research to tropical open
  30. Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/herbert-freddie-gutfreund/
    Thumbnail for Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology 18 Nov 2021: Herbert ‘Freddie’ Gutfreund Freddie Gutfreund was born in Vienna on 21st October 1921. In 1938, aged 17, he arrived in England as a refugee, initially to
  31. Furin protease is not essential for SARS-CoV-2 infection - MRC…

    https://www2.mrc-lmb.cam.ac.uk/furin-protease-is-not-essential-for-sars-cov-2-infection/
    Thumbnail for Furin protease is not essential for SARS-CoV-2 infection - MRC Laboratory of Molecular Biology 29 Jan 2021: This process might play a role in virus spread between cells even in the absence of production of new virus particles. ... The emergence of new SARS-CoV-2 variants is a real concern as they can threaten the effectiveness of the approved SARS-CoV-2
  32. Coot Scripting Interface: get-monomer.hh Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/get-monomer_8hh_source.html
    24 Aug 2021: 43 // return a new molecule number.
  33. Behind the Scenes with... Steve Scotcher - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/steve-scotcher/
    Thumbnail for Behind the Scenes with... Steve Scotcher - MRC Laboratory of Molecular Biology 31 Mar 2021: Original hand-drawn design from the 1980s. Before a new piece of equipment or machinery can be made, we first need to nail down the design. ... More recently, I’ve worked with Richard Henderson and Greg McMullan on various high vacuum test rigs for the
  34. Graeme Mitchison (1944 - 2018) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/graeme-mitchison-1944-2018/
    Thumbnail for Graeme Mitchison (1944 - 2018) - MRC Laboratory of Molecular Biology 30 Mar 2021: Graeme continued to keep in touch with colleagues and friends at LMB, including celebrating the opening of the new LMB building at the LMB Alumni Symposium in 2014. ... Richard Durbin and the LMB News Team. Primary Sidebar. Search. Search this website.
  35. Ken Harvey (1926 – 2021) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/ken-harvey-1926-2021/
    Thumbnail for Ken Harvey (1926 – 2021) - MRC Laboratory of Molecular Biology 22 Jul 2021: Ken Harvey (1926 – 2021) Ken Harvey joined the LMB on 21st June 1965, as the LMB’s first photographer. He went on to become Head of the Photography
  36. John Abelson - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-john-abelson/
    Thumbnail for John Abelson - MRC Laboratory of Molecular Biology 30 Mar 2021: John Abelson John Abelson was a postdoc in the Structural Studies Division at LMB from 1965 to 1968, working with Sydney Brenner and Francis Crick on
  37. Coot Scripting Interface: cc-interface.hh File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/cc-interface_8hh.html
    24 Aug 2021: Returns. the molecule number of the new map. Return -1 if unable to make a variance map. ... the function passed to lbg, so that it calls it when a new SBase comp_id is required.
  38. Sjors Scheres awarded the Leeuwenhoek Medal from the Royal Society -…

    https://www2.mrc-lmb.cam.ac.uk/sjors-scheres-awarded-the-leeuwenhoek-medal-from-the-royal-society/
    Thumbnail for Sjors Scheres awarded the Leeuwenhoek Medal from the Royal Society - MRC Laboratory of Molecular Biology 24 Aug 2021: For his ground-breaking methodological developments in image processing and analysis in cryo-EM, Sjors Scheres has been awarded the Royal Society’s Leeuwenhoek Medal.
  39. Uli Arndt (1924 - 2006) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-uli-arndt-1924-2006/
    Thumbnail for Uli Arndt (1924 - 2006) - MRC Laboratory of Molecular Biology 30 Mar 2021: Uli Arndt (1924 - 2006) His many friends and colleagues around the world will be very sad to learn that Uli died on 24th March, aged 81, from cancer which
  40. How DNA damage induces appetite suppression and weight loss - MRC…

    https://www2.mrc-lmb.cam.ac.uk/how-dna-damage-induces-appetite-suppression-and-weight-loss/
    Thumbnail for How DNA damage induces appetite suppression and weight loss - MRC Laboratory of Molecular Biology 24 Nov 2021: DNA damage caused by formaldehyde is repaired involving CSA and CSB genes. KJ Patel’s lab have shown how, when this pathway is mutated such as in people with Cockayne syndrome, the appetite suppression hormone GDF15 is released leading to severe
  41. M. Madan Babu elected Fellow of the Academy of Medical Sciences - MRC …

    https://www2.mrc-lmb.cam.ac.uk/m-madan-babu-elected-fellow-of-the-academy-of-medical-sciences/
    Thumbnail for M. Madan Babu elected Fellow of the Academy of Medical Sciences - MRC Laboratory of Molecular Biology 12 May 2021: M. Madan Babu, former group leader in the LMB’s Structural Studies Division, has been elected into the Fellowship of the Academy of Medical Sciences.
  42. John Kendrew (1917 - 1997) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/john-kendrew-1917-1997/
    Thumbnail for John Kendrew (1917 - 1997) - MRC Laboratory of Molecular Biology 30 Mar 2021: John Kendrew (1917 - 1997) In 1945, John Kendrew joined Max Perutz at the Cavendish Laboratory in Cambridge. Together they would share three great
  43. Richard Perham (1937 - 2015) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/richard-perham-1937-2015/
    Thumbnail for Richard Perham (1937 - 2015) - MRC Laboratory of Molecular Biology 30 Mar 2021: Richard Perham (1937 - 2015) Richard Perham died on Saturday 14 February 2015, after a short illness, at the age of 77. Richard began as a PhD student in
  44. LMB honoured in Cambridge Independent Science and Technology Awards - …

    https://www2.mrc-lmb.cam.ac.uk/lmb-honoured-in-cambridge-independent-science-and-technology-awards/
    Thumbnail for LMB honoured in Cambridge Independent Science and Technology Awards - MRC Laboratory of Molecular Biology 20 Apr 2021: The LMB has received a Special Commendation in the category of Covid-19 Response Award, in the Cambridge Independent Science and Technology Awards. Also
  45. Gerry Rubin: Looking Back - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/gerry-rubin/
    Thumbnail for Gerry Rubin: Looking Back - MRC Laboratory of Molecular Biology 31 Mar 2021: Gerry Rubin: Looking Back Gerry Rubin was a PhD student in the Cell Biology Division from 1971-1974. For the December 2019 LMB Alumni Newsletter, he
  46. KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=21355
    27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  47. 27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  48. Coot Scripting Interface: probe-clash-score.hh Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/probe-clash-score_8hh_source.html
    24 Aug 2021: 100 }. 101 }. 102 if (! found) {. 103 one_way_probe_contact_t new_contact(from_atom);. ... 104 new_contact.add(to_atom);.
  49. Getting close to nature: results of the 2020 Science Image Award… -…

    https://www2.mrc-lmb.cam.ac.uk/getting-close-to-nature-results-of-the-2020-science-image-award/
    Thumbnail for Getting close to nature: results of the 2020 Science Image Award… - MRC Laboratory of Molecular Biology 5 May 2021: Fourteen primary schools participated in the 2020 Science Image Award competition, with the winning image taken by a child at Barnham Primary School near Thetford.
  50. Setting the stage: development of sample holders for electron ...

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=21295
    21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.
  51. Maria Leptin has been appointed President of the European Research…

    https://www2.mrc-lmb.cam.ac.uk/maria-leptin-has-been-appointed-president-of-the-european-research-council/
    Thumbnail for Maria Leptin has been appointed President of the European Research Council - MRC Laboratory of Molecular Biology 2 Jul 2021: Published on. 2 July, 2021. Maria Leptin is the new President of the European Research Council starting from 1 October 2021.

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