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  2. Why humans have such big brains - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/why-humans-have-such-big-brains/
    Thumbnail for Why humans have such big brains - MRC Laboratory of Molecular Biology 6 Apr 2021: The Guardian covers how Madeline Lancaster’s group in the Cell Biology division has used brain organoids to trace the origin of human’s larger brain size
  3. New structures show how auxiliary subunits modulate hippocampal AMPA…

    https://www2.mrc-lmb.cam.ac.uk/new-structures-show-how-auxiliary-subunits-modulate-hippocampal-ampa-receptor-neurotransmission/
    Thumbnail for New structures show how auxiliary subunits modulate hippocampal AMPA receptor neurotransmission - MRC Laboratory of Molecular Biology 2 Jun 2021: Search this website. New structures show how auxiliary subunits modulate hippocampal AMPA receptor neurotransmission. ... New structures show how auxiliary subunits modulate hippocampal AMPA receptor neurotransmission.
  4. Marta Shahbazi on being a mother scientist - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/marta-shahbazi-on-being-a-mother-scientist/
    Thumbnail for Marta Shahbazi on being a mother scientist - MRC Laboratory of Molecular Biology 19 May 2021: Cell Biology Division) and her experience of juggling being a new group leader and a new mother during lockdown.
  5. Cell scientist to watch – Alexey Amunts - MRC Laboratory of Molecular …

    https://www2.mrc-lmb.cam.ac.uk/cell-scientist-to-watch-alexey-amunts/
    Thumbnail for Cell scientist to watch – Alexey Amunts - MRC Laboratory of Molecular Biology 1 Jul 2021: Alexey Amunts shares insights into his career to date, including his time at the LMB in Venki Ramakrishnan’s lab, the importance of open science and
  6. Tanmay Bharat awarded 2021 Eppendorf Award - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/tanmay-bharat-awarded-2021-eppendorf-award/
    Thumbnail for Tanmay Bharat awarded 2021 Eppendorf Award - MRC Laboratory of Molecular Biology 25 Jun 2021: Tanmay Bharat has been awarded the 2021 Eppendorf Award for Young European Investigators for his research on the structure and function of protective
  7. The race to repurpose nature’s protein factories - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/the-race-to-repurpose-natures-protein-factories/
    Thumbnail for The race to repurpose nature’s protein factories - MRC Laboratory of Molecular Biology 9 Feb 2021: Published on. 9 February, 2021. A C&EN feature about research aiming to enable ribosomes to make new drugs and materials through use of a wider variety of substrates, including key
  8. Coot Scripting Interface: c-interface-generic-objects.h File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface-generic-objects_8h.html
    24 Aug 2021: new_generic_object_number (const std::string &obj_name). create a new generic object with name objname More.. ... int new_generic_object_number. (. const std::string &. obj_name. ). create a new generic object with name objname.
  9. Covid19 Image - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/download/covid19-image-download/
    Thumbnail for Covid19 Image - MRC Laboratory of Molecular Biology 30 Mar 2021: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Downloads
  10. Ben Nichols - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/ben-nichols/
    Thumbnail for Ben Nichols - MRC Laboratory of Molecular Biology 30 Mar 2021: Ben Nichols Ben Nichols first joined the LMB’s Cell Biology Division in 1996, as a postdoctoral scientist in Hugh Pelham’s group, working on yeast
  11. LMB-Timeline-poster 2020 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/download/lmb-timeline-poster-2019/
    Thumbnail for LMB-Timeline-poster 2020 - MRC Laboratory of Molecular Biology 7 Jul 2021: One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. Search this website. Downloads
  12. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x6e.html
    24 Aug 2021: new_generic_object_number_for_molecule() : c-interface-generic-objects.h. ... new_molecule_by_symmetry_with_atom_selection() : c-interface.h.
  13. Grant Jacobs - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/grant-jacobs/
    Thumbnail for Grant Jacobs - MRC Laboratory of Molecular Biology 17 Nov 2021: Since then he has travelled in Asia and Central Asia, returning to his home country, New Zealand.
  14. Coot Scripting Interface: get-monomer.hh File Reference

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/get-monomer_8hh.html
    24 Aug 2021: Returns. the new molecule number, if not -1 (error). Generated by . 1.8.5.
  15. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x6e.html
    24 Aug 2021: new_generic_object_number_for_molecule() : c-interface-generic-objects.h. ... new_molecule_by_symmetry_with_atom_selection() : c-interface.h.
  16. Alex Bateman elected to membership of EMBO - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/alex-bateman-elected-to-membership-of-embo/
    Thumbnail for Alex Bateman elected to membership of EMBO - MRC Laboratory of Molecular Biology 9 Jun 2021: Alex Bateman, a former PhD student in Cyrus Chothia’s group in the Structural Studies Division, has been elected a member of EMBO for his work on protein
  17. Brian Hartley (1926 – 2021) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/brian-hartley-1926-2021/
    Thumbnail for Brian Hartley (1926 – 2021) - MRC Laboratory of Molecular Biology 7 May 2021: rd. May 2021. Brian made outstanding contributions to protein chemistry, with his invention of new analytical methods, and produced for the first time an understanding of the properties of proteolytic enzymes ... Brian continued his work on the sequence
  18. How did the chemical reaction of life begin? - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/how-did-the-chemical-reaction-of-life-begin/
    Thumbnail for How did the chemical reaction of life begin? - MRC Laboratory of Molecular Biology 14 Oct 2021: Group Leader John Sutherland discusses his argument that solar UV light is the energy source required to drive the chemical reactions that make the
  19. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  20. Apprentices complete their training at the LMB - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/apprentices-complete-their-training-at-the-lmb/
    Thumbnail for Apprentices complete their training at the LMB - MRC Laboratory of Molecular Biology 21 Jun 2021: It was a good experience; I learnt a lot of new things and became more confident in the lab whilst gaining new qualifications. ... This apprenticeship gave Emma the opportunity to learn whilst she earnt and provided additional support as she retrained
  21. Testing the capacity for intracellular antibodies to neutralise…

    https://www2.mrc-lmb.cam.ac.uk/testing-the-capacity-for-intracellular-antibodies-to-neutralise-sars-cov-2/
    Thumbnail for Testing the capacity for intracellular antibodies to neutralise SARS-CoV-2 - MRC Laboratory of Molecular Biology 29 Jul 2021: Leo James’ group, in the LMB’s PNAC Division, has developed a new assay that can measure the anti-viral activity of anti-N antibodies in blood samples. ... how many new virions are produced or quantifying the amount of viral RNA present.
  22. Per Bullough - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/lmb-alumni-per-bullough/
    Thumbnail for Per Bullough - MRC Laboratory of Molecular Biology 30 Mar 2021: Search this website. Per Bullough. Per Bullough was a Ph.D. student in the Structural Studies Division at LMB from 1985-1989 developing new methods of low-dose imaging of biological
  23. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  24. Packaging molecular motors for delivery - MRC Laboratory of Molecular …

    https://www2.mrc-lmb.cam.ac.uk/packaging-molecular-motors-for-delivery/
    Thumbnail for Packaging molecular motors for delivery - MRC Laboratory of Molecular Biology 26 Feb 2021: The airways in our lungs are kept clear of mucus by the rhythmic beating motion of slender cellular extensions called cilia, driven by dynein motors. Andrew Carter’s group, has discovered a novel protein that packages these molecular motors for
  25. Madeline Lancaster appointed as 2021 Vallee Scholar - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-appointed-as-2021-vallee-scholar/
    Thumbnail for Madeline Lancaster appointed as 2021 Vallee Scholar - MRC Laboratory of Molecular Biology 13 Sep 2021: in our brain and produce new virus within choroid plexus (ChP) epithelial cells, which may cause long-term neurological impacts such as chronic fatigue.
  26. Engaging online for the first Cambridge Festival - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/engaging-online-for-the-first-cambridge-festival/
    Thumbnail for Engaging online for the first Cambridge Festival - MRC Laboratory of Molecular Biology 4 May 2021: LMB scientists contribute to the Cambridge Festival with a livestreamed lab tour and a set of activities showing how studying worms can help us understand our brains
  27. Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/geoffrey-grigg/
    Thumbnail for Geoffrey Grigg (1926 - 2008) - MRC Laboratory of Molecular Biology 21 May 2021: Geoffrey Grigg (1926 - 2008) Geoffrey Grigg was an Australian visitor to the LMB with Fred Sanger in 1972-1974 and Greg Winter in 1988, and often visited
  28. “The LMB provides an unsurpassed environment for both new ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=18852
    18 Jan 2021: cell type that controls the start of allergic asthma, providing a critical first step in developing new. ... to solve the structureof the ribosome and is. informing work to develop new antibiotics.
  29. Tail of SARS-CoV-2 Spike protein is optimised to reach the cell…

    https://www2.mrc-lmb.cam.ac.uk/tail-of-sars-cov-2-spike-protein-is-optimised-to-reach-the-cell-surface-causing-infection-to-spread-to-neighbouring-cells/
    Thumbnail for Tail of SARS-CoV-2 Spike protein is optimised to reach the cell surface causing infection to spread to neighbouring cells - MRC Laboratory of Molecular Biology 10 Sep 2021: Most of these new Spike proteins accumulate in an intracellular structure named Golgi which assembles new viruses. ... the Golgi apparatus, then hold it there whilst new viruses are made.
  30. Early transcriptional patterning of a forming tissue is essential to…

    https://www2.mrc-lmb.cam.ac.uk/early-transcriptional-patterning-of-a-forming-tissue-is-essential-to-morphogenesis-of-a-tubular-organ/
    Thumbnail for Early transcriptional patterning of a forming tissue is essential to morphogenesis of a tubular organ - MRC Laboratory of Molecular Biology 8 Nov 2021: Time-lapse quantitative study of developing salivary glands in Drosophila embryos, conducted by Katja Röper’s group, reveals the key control factors behind cells’ behavioural transitions that are essential for correct organ formation.
  31. Mike Clark - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/mike-clark/
    Thumbnail for Mike Clark - MRC Laboratory of Molecular Biology 30 Mar 2021: Mike Clark Mike Clark was a Ph.D. student working with Cesar Milstein from 1978-1981 carrying out research into the recently described technology of
  32. Alex Betz - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/alex-betz/
    Thumbnail for Alex Betz - MRC Laboratory of Molecular Biology 30 Mar 2021: Alexander Betz Alex joined the PNAC Division in 1997 as a Programme Leader Track, before becoming a Programme Leader in 2008. He left the LMB in September
  33. The Coot User Manual

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html
    1 Mar 2021: The Coot User Manual
  34. KENDREW LECTURE(Part 1) Demis HassabisFounder & CEO DeepMind,…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21355
    27 Sep 2021: Using AI to accelerate scientific discoveryWednesday 13th October @ 2.30 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  35. KENDREW LECTURE(Part 2) Wednesday 13th October @ 4.00 pmDetails ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21356
    27 Sep 2021: KENDREW LECTURE(Part 2). Wednesday 13th October @ 4.00 pmDetails on the LMB website https://www2.mrc-lmb.cam.ac.uk/news-and-events/scientific-seminars/.
  36. Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf
    26 Jul 2021: Abstract. Many new structures of membrane proteins have been determined over the last decade, yet thenature of protein–lipid interplay has received scant attention. ... Plenum Press, New York). 18. Liu Y-T, Tao C-L, Zhang X, Xia W, Shi D-Q, Qi L, Xu C,
  37. Coot Scripting Interface: cc-interface.hh Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/cc-interface_8hh_source.html
    24 Aug 2021: 474 // return the status and vector of chain-ids of the new chain ids. ... 1312 mmdb::Manager new_molecule_by_symmetry_matrix_from_molecule(mmdb::Manager mol,.
  38. Dinolite Instructions

    https://www2.mrc-lmb.cam.ac.uk/microscopes4schools/downloads/dinolite_instructions_detailed_2021.22_LJM.doc
    18 Oct 2021: If no new image appears, move the mouse until it does (you may see the last image taken otherwise). ... 5. To take a new image, place your mouse over anything other than an existing thumbnail.
  39. Behind the scenes: Paul Hart and the development of IT at the LMB -…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-paul-hart-and-the-development-of-it-at-the-lmb/
    Thumbnail for Behind the scenes: Paul Hart and the development of IT at the LMB - MRC Laboratory of Molecular Biology 20 Dec 2021: The biggest challenge. Several year later the new building project came my way. ... I’d worked on a couple of new building projects, but never as a lead.
  40. Coot Scripting Interface: c-interface.h Source File

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html
    24 Aug 2021: 447. 457 int add_ligand_delete_residue_copy_molecule(int imol_ligand_new,. ... If it doesn't then we /. 1527 / go down a (new 20060920) different path. /.
  41. Setting the stage: development of sample holders for electron ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/www2.mrc-lmb.cam.ac.uk/?wpdmdl=21295
    21 Jun 2021: Also, parts can move during specimen translation, making a new contact with small temperature differences between the contacting parts. ... 1996 Bob Morrison of Gatan Inc., designed a holder for a new Phillips prototype to be used with liquid helium.
  42. Behind the scenes: Maria Daly and the flow cytometry facility - MRC…

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/share-your-memories/behind-the-scenes-maria-daly-and-the-flow-cytometry-facility/
    Thumbnail for Behind the scenes: Maria Daly and the flow cytometry facility - MRC Laboratory of Molecular Biology 31 Mar 2021: Behind the scenes: Maria Daly and the flow cytometry facility Maria Daly is manager of the LMB’s Flow Cytometry Facility, which provides LMB scientists
  43. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_func_0x75.html
    24 Aug 2021: update_go_to_atom_window_on_new_mol() : c-interface.h.
  44. Cryo‐EM structure of the full‐length Lon protease from Thermus…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf
    14 Nov 2021: The new model containing a coiled-coil. a-helix describes map 2 well. ... Hagen WJH, Lindahl E and Scheres SHW (2018) New. tools for automated high-resolution cryo-EM structure.
  45. BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf
    29 Aug 2021: High-resolution structure deter-mination may aid in these directions as new compounds are developed andtested as treatments for COVID-19. ... 9, 2. 021. 20. J. Zivanov et al., New tools for automated high-resolution cryo-EM structuredetermination in
  46. Coot Scripting Interface: File Members

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/globals_0x64.html
    24 Aug 2021: default_new_atoms_b_factor() : c-interface.h.
  47. LMB scientists honoured by Biochemical Society Awards - MRC…

    https://www2.mrc-lmb.cam.ac.uk/lmb-scientists-honoured-by-biochemical-society-awards/
    Thumbnail for LMB scientists honoured by Biochemical Society Awards - MRC Laboratory of Molecular Biology 30 Mar 2021: This award is given every three years to recognise exemplary work leading to the development of a new method or reagent. ... Recently, Maria has used an integrative approach combining data on transcriptomics, genomics, proteomics, receptor sequence and
  48. Heart cell clocks help coordinate daily cardiac function - MRC…

    https://www2.mrc-lmb.cam.ac.uk/heart-cell-clocks-help-coordinate-daily-cardiac-function/
    Thumbnail for Heart cell clocks help coordinate daily cardiac function - MRC Laboratory of Molecular Biology 21 Oct 2021: Cell Biology Group Leader, John O’Neill, discusses his group’s recent paper. Their work highlights how heart cells regulate daily function through
  49. Pathway behind disposal of ‘orphan’ proteins identified - MRC…

    https://www2.mrc-lmb.cam.ac.uk/pathway-behind-disposal-of-orphan-proteins-identified/
    Thumbnail for Pathway behind disposal of ‘orphan’ proteins identified - MRC Laboratory of Molecular Biology 27 Aug 2021: This new insight, that an assembly factor can also recruit degradation factors such as HERC1, might apply to many other protein complexes in the cell that rely on their own specialised ... Therefore, identification of quality control factors such as
  50. Madeline Lancaster on serendipity and adventure in science - MRC…

    https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-on-serendipity-and-adventure-in-science/
    Thumbnail for Madeline Lancaster on serendipity and adventure in science - MRC Laboratory of Molecular Biology 22 Sep 2021: Cell Biology Group Leader Madeline Lancaster discusses how her ‘failed’ attempt to grow neural stem cells led to the development of brain organoids –
  51. John Finch Collection - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/john-finch-collection/
    Thumbnail for John Finch Collection - MRC Laboratory of Molecular Biology 31 Mar 2021: He came to the new LMB in 1962 with the Birkbeck group, which was now led by Aaron Klug after Rosalind’s death in 1958.

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